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Select item 111501281.

Role of NLRP3 Inflammasomes in Monocyte and Microglial Recruitments in Choroidal Neovascularization

Blake W. Dieckmann, Marcell E. Paguaga, Gary W. McCollum, John S. Penn, MD Imam Uddin

Immunohorizons. 2024 May; 8(5): 363–370. Published online 2024 May 22. doi: 10.4049/immunohorizons.2400025

PMCID:: PMC11150128

Abstract Article PDF–1.5M

Select item 111442682.

PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium

Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, Nady Golestaneh

Cell Death Dis. 2024 Jun; 15(6): 385. Published online 2024 Jun 1. doi: 10.1038/s41419-024-06762-y

PMCID:: PMC11144268

Abstract Article PDF–13M

Select item 111319933.

Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

Aging (Albany NY) 2024 May 15; 16(9): 8044–8069. Published online 2024 May 10. doi: 10.18632/aging.205804

PMCID:: PMC11131993

Abstract Article PDF–5.1M

Select item 111274954.

Cláudia Farinha, Patrícia Barreto, Rita Coimbra, Maria Beatriz Machado, Inês Figueiredo, Maria Luz Cachulo, José Cunha-Vaz, Rufino Silva

Invest Ophthalmol Vis Sci. 2024 May; 65(5): 35. Published online 2024 May 22. doi: 10.1167/iovs.65.5.35

PMCID:: PMC11127495

Abstract Article PDF–1.0M

Select item 111150985.

Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization

Julie Lecomte, Krystel Louis, Benoit Detry, Silvia Blacher, Vincent Lambert, Sandrine Bekaert, Carine Munaut, Jenny Paupert, Pierre Blaise, Jean-Michel Foidart, Jean-Marie Rakic, Stephen M. Krane, Agnès Noel

Cell Mol Life Sci. 2011 Feb; 68(4): 677–686. Published online 2010 Aug 11. doi: 10.1007/s00018-010-0476-6

PMCID:: PMC11115098

Abstract Article PDF–657K

Select item 111149286.

Expression and distribution of immunoglobulin G and its receptors in an immune privileged site: the eye

Na Niu, Jie Zhang, Yingui Sun, Shuna Wang, Yonghong Sun, Christine Korteweg, Weiwei Gao, Jiang Gu

Cell Mol Life Sci. 2011 Jul; 68(14): 2481–2492. Published online 2010 Nov 9. doi: 10.1007/s00018-010-0572-7

PMCID:: PMC11114928

Abstract Article PDF–993K

Select item 111116917.

Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region

Yanjie Li, Yuehua Wei, Mark Ultsch, Wei Li, Wanjian Tang, Benjamin Tombling, Xinxin Gao, Yoana Dimitrova, Christian Gampe, Jakob Fuhrmann, Yingnan Zhang, Rami N. Hannoush, Daniel Kirchhofer

Nat Commun. 2024; 15: 4359. Published online 2024 May 22. doi: 10.1038/s41467-024-48655-w

PMCID:: PMC11111691

Abstract Article PDF–2.4M

Select item 111087898.

Prognostication in Stargardt Disease Using Fundus Autofluorescence: Improving Patient Care

Malena Daich Varela, Yannik Laich, Shaima Awadh Hashem, Omar A. Mahroo, Andrew R. Webster, Michel Michaelides

Ophthalmology. 2023 Nov; 130(11): 1182–1190. doi: 10.1016/j.ophtha.2023.06.010

PMCID:: PMC11108789

Abstract Article PDF–901K

Select item 111079519.

Near Infrared Autofluorescence Lifetime Imaging of Human Retinal Pigment Epithelium Using Adaptive Optics Scanning Light Ophthalmoscopy

Karteek Kunala, Janet A. H. Tang, Kristen E. Bowles Johnson, Khang T. Huynh, Keith Parkins, Hye-Jin Kim, Qiang Yang, Janet R. Sparrow, Jennifer J. Hunter

Invest Ophthalmol Vis Sci. 2024 May; 65(5): 27. Published online 2024 May 17. doi: 10.1167/iovs.65.5.27

PMCID:: PMC11107951

Abstract Article PDF–9.4M

Select item 1110773410.

Periostin in vitreoretinal diseases

Shigeo Yoshida, Takahito Nakama, Keijiro Ishikawa, Shintaro Nakao, Koh-hei Sonoda, Tatsuro Ishibashi

Cell Mol Life Sci. 2017 Dec; 74(23): 4329–4337. Published online 2017 Sep 14. doi: 10.1007/s00018-017-2651-5

PMCID:: PMC11107734

Abstract Article PDF–889K

Select item 1110737011.

Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice

Dominik Lewandowski, Fangyuan Gao, Sanae Imanishi, Aleksander Tworak, Marco Bassetto, Zhiqian Dong, Antonio F.M. Pinto, Marcin Tabaka, Philip D. Kiser, Yoshikazu Imanishi, Dorota Skowronska-Krawczyk, Krzysztof Palczewski

J Biol Chem. 2024 May; 300(5): 107291. Published online 2024 Apr 16. doi: 10.1016/j.jbc.2024.107291

PMCID:: PMC11107370

Abstract Article PDF–7.1M

Select item 1110545412.

Mitochondrial quality control in AMD: does mitophagy play a pivotal role?

Juha M. T. Hyttinen, Johanna Viiri, Kai Kaarniranta, Janusz Błasiak

Cell Mol Life Sci. 2018 Aug; 75(16): 2991–3008. Published online 2018 May 18. doi: 10.1007/s00018-018-2843-7

PMCID:: PMC11105454

Abstract Article PDF–1.4M

Select item 1108163113.

Pigmentation level of human iPSC-derived RPE does not indicate a specific gene expression profile

Yoko Nakai-Futatsugi, Jianshi Jin, Taisaku Ogawa, Noriko Sakai, Akiko Maeda, Ken-ichi Hironaka, Masakazu Fukuda, Hiroki Danno, Yuji Tanaka, Seiji Hori, Katsuyuki Shiroguchi, Masayo Takahashi

eLife. 2024; 12: RP92510. Published online 2024 May 9. doi: 10.7554/eLife.92510

PMCID:: PMC11081631

Abstract Article PDF–2.5M

Select item 1107270714.

Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases

Fátima Milhano dos Santos, Sergio Ciordia, Joana Mesquita, João Paulo Castro de Sousa, Alberto Paradela, Cândida Teixeira Tomaz, Luís António Paulino Passarinha

Cell Mol Life Sci. 2023 Jan; 80(1): 22. Published online 2022 Dec 31. doi: 10.1007/s00018-022-04670-y

PMCID:: PMC11072707

Abstract Article PDF–8.4M

Select item 1107209515.

Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway

Yi-Hsun Huang, Cheng-Hsiang Kuo, I-Chen Peng, Yi-Sheng Chang, Sung-Huei Tseng, Edward M. Conway, Hua-Lin Wu

Cell Mol Life Sci. 2021 Dec; 78(23): 7681–7692. Published online 2021 Oct 27. doi: 10.1007/s00018-021-03950-3

PMCID:: PMC11072095

Abstract Article PDF–7.4M

Select item 1105980416.

CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration

Rayne R. Lim, Sharlene Shirali, Jessica Rowlan, Abbi L. Engel, Marcos Nazario,, Jr., Kelie Gonzalez, Aspen Tong, Jay Neitz, Maureen Neitz, Jennifer R. Chao

Invest Ophthalmol Vis Sci. 2024 Apr; 65(4): 43. Published online 2024 Apr 29. doi: 10.1167/iovs.65.4.43

PMCID:: PMC11059804

Abstract Article PDF–3.2M

Select item 1105048717.

The Role of Glutathione in Age-Related Macular Degeneration (AMD)

Sylwia Brodzka, Jędrzej Baszyński, Katarzyna Rektor, Karolina Hołderna-Bona, Emilia Stanek, Natalia Kurhaluk, Halina Tkaczenko, Grażyna Malukiewicz, Alina Woźniak, Piotr Kamiński

Int J Mol Sci. 2024 Apr; 25(8): 4158. Published online 2024 Apr 9. doi: 10.3390/ijms25084158

PMCID:: PMC11050487

Abstract Article PDF–2.9M

Select item 1104950918.

Causal Associations of Glaucoma and Age-Related Macular Degeneration with Cataract: A Bidirectional Two-Sample Mendelian Randomisation Study

Je Hyun Seo, Young Lee

Genes (Basel) 2024 Apr; 15(4): 413. Published online 2024 Mar 26. doi: 10.3390/genes15040413

PMCID:: PMC11049509

Abstract Article PDF–2.1M

Select item 1104483719.

Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus

Brandi L. Williams, Moussa A. Zouache, Nathan A. Seager, Chris M. Pappas, Jin Liu, Robert A. Anstadt, William C. Hubbard, Julie Thomas, Jill L. Hageman, Jennifer Mohler, Burt T. Richards, Gregory S. Hageman

Invest Ophthalmol Vis Sci. 2024 Apr; 65(4): 34. Published online 2024 Apr 22. doi: 10.1167/iovs.65.4.34