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Items: 1 to 20 of 51

1.
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance
Sara G. Danielli, Ermelinda Porpiglia, Andrea J. De Micheli, Natalia Navarro, Michael J. Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G. Marques, Stephanie Kasper, Peter K. Bode, Anton G. Henssen, Dennis Gürgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M. Blau, Marco Wachtel, Beat W. Schäfer
Sci Adv. 2023 Feb; 9(6): eade9238. Published online 2023 Feb 8. doi: 10.1126/sciadv.ade9238
PMCID:
PMC9908029
ArticlePubReaderPDF–2.7MCite
2.
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma
Tilman L. B. Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J. Jacobi, Cornelius M. Funk, Florian H. Geyer, Jing Li, Ignazio Piseddu, Bruno L. Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G. P. Grünewald, Maximilian M. L. Knott
Mol Cancer. 2022; 21: 199. Published online 2022 Oct 13. doi: 10.1186/s12943-022-01641-6
PMCID:
PMC9558418
ArticlePubReaderPDF–1.7MCite
3.
Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma
Shivendra Singh, Ahmed Abu-Zaid, Hongjian Jin, Jie Fang, Qiong Wu, Tingting Wang, Helin Feng, Waise Quarni, Ying Shao, Lily Maxham, Alireza Abdolvahabi, Mi-Kyung Yun, Sivaraja Vaithiyalingam, Haiyan Tan, John Bowling, Victoria Honnell, Brandon Young, Yian Guo, Richa Bajpai, Shondra M. Pruett-Miller, Gerard C Grosveld, Mark Hatley, Beisi Xu, Yiping Fan, Gang Wu, Eleanor Y. Chen, Taosheng Chen, Peter W. Lewis, Zoran Rankovic, Yimei Li, Andrew J. Murphy, John Easton, Junmin Peng, Xiang Chen, Ruoning Wang, Stephen W. White, Andrew M. Davidoff, Jun Yang
Sci Transl Med. Author manuscript; available in PMC 2023 Jan 13.
Published in final edited form as: Sci Transl Med. 2022 Jul 13; 14(653): eabq2096. Published online 2022 Jul 13. doi: 10.1126/scitranslmed.abq2096
PMCID:
PMC9548378
ArticlePubReaderPDF–2.9MCite
4.
BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma
Dominik Laubscher, Berkley E. Gryder, Benjamin D. Sunkel, Thorkell Andresson, Marco Wachtel, Sudipto Das, Bernd Roschitzki, Witold Wolski, Xiaoli S. Wu, Hsien-Chao Chou, Young K. Song, Chaoyu Wang, Jun S. Wei, Meng Wang, Xinyu Wen, Quy Ai Ngo, Joana G. Marques, Christopher R. Vakoc, Beat W. Schäfer, Benjamin Z. Stanton, Javed Khan
Nat Commun. 2021; 12: 6924. Published online 2021 Nov 26. doi: 10.1038/s41467-021-27176-w
PMCID:
PMC8626462
ArticlePubReaderPDF–3.6MCite
5.
Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium
Jack F. Shern, Joanna Selfe, Elisa Izquierdo, Rajesh Patidar, Hsien-Chao Chou, Young K. Song, Marielle E. Yohe, Sivasish Sindiri, Jun Wei, Xinyu Wen, Erin R. Rudzinski, Donald A. Barkauskas, Tammy Lo, David Hall, Corinne M. Linardic, Debbie Hughes, Sabri Jamal, Meriel Jenney, Julia Chisholm, Rebecca Brown, Kristine Jones, Belynda Hicks, Paola Angelini, Sally George, Louis Chesler, Michael Hubank, Anna Kelsey, Susanne A. Gatz, Stephen X. Skapek, Douglas S. Hawkins, Janet M. Shipley, Javed Khan
J Clin Oncol. 2021 Sep 10; 39(26): 2859–2871. Published online 2021 Jun 24. doi: 10.1200/JCO.20.03060
PMCID:
PMC8425837
ArticlePubReaderPDF–1.1MCite
6.
Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target
Cara E. Shields, Sindhu Potlapalli, Selma M. Cuya‐Smith, Sarah K. Chappell, Dongdong Chen, Daniel Martinez, Jennifer Pogoriler, Komal S. Rathi, Shiv A. Patel, Kristianne M. Oristian, Corinne M. Linardic, John M. Maris, Karmella A. Haynes, Robert W. Schnepp
Mol Oncol. 2021 Aug; 15(8): 2156–2171. Published online 2021 Mar 27. doi: 10.1002/1878-0261.12914
PMCID:
PMC8333775
ArticlePubReaderPDF–2.2MCite
7.
Germline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children’s Oncology Group
He Li, Saumya D Sisoudiya, Bailey A Martin-Giacalone, Michael M Khayat, Shannon Dugan-Perez, Deborah A Marquez-Do, Michael E Scheurer, Donna Muzny, Eric Boerwinkle, Richard A Gibbs, Yueh-Yun Chi, Donald A Barkauskas, Tammy Lo, David Hall, Douglas R Stewart, Joshua D Schiffman, Stephen X Skapek, Douglas S Hawkins, Sharon E Plon, Aniko Sabo, Philip J Lupo
J Natl Cancer Inst. 2021 Jul; 113(7): 875–883. Published online 2020 Dec 29. doi: 10.1093/jnci/djaa204
PMCID:
PMC8246828
ArticlePubReaderPDF–1.5MCite
8.
A human Myogenin promoter modified to be highly active in alveolar rhabdomyosarcoma drives an effective suicide gene therapy
Johanna Pruller, Isabella Hofer, Massimo Ganassi, Philipp Heher, Michelle T. Ma, Peter S. Zammit
Cancer Gene Ther. 2021; 28(5): 427–441. Published online 2020 Sep 25. doi: 10.1038/s41417-020-00225-0
Correction in:
Cancer Gene Ther. 2021; 28(5): 544.
PMCID:
PMC8119243
ArticlePubReaderPDF–4.1MCite
9.
Refractory alveolar rhabdomyosarcoma in an 11-year-old male
Cora A. Ricker, Andrew D. Woods, William Simonson, Melvin Lathara, Ganapati Srinivasa, Erin R. Rudzinski, Atiya Mansoor, Robert G. Irwin, Charles Keller, Noah E. Berlow
Cold Spring Harb Mol Case Stud. 2021 Feb; 7(1): a005983. doi: 10.1101/mcs.a005983
PMCID:
PMC7903883
ArticlePubReaderPDF–10MCite
10.
A method to culture human alveolar rhabdomyosarcoma cell lines as rhabdospheres demonstrates an enrichment in stemness and Notch signaling
Katherine K. Slemmons, Michael D. Deel, Yi-Tzu Lin, Kristianne M. Oristian, Nina Kuprasertkul, Katia C. Genadry, Po-Han Chen, Jen-Tsan Ashley Chi, Corinne M. Linardic
Biol Open. 2021 Feb 15; 10(2): bio050211. Published online 2021 Feb 9. doi: 10.1242/bio.050211
PMCID:
PMC7888706
ArticlePubReaderPDF–4.8MCite
11.
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
Silvia Pomella, Prethish Sreenivas, Berkley E. Gryder, Long Wang, David Milewski, Matteo Cassandri, Kunal Baxi, Nicole R. Hensch, Elena Carcarino, Young Song, Hsien-Chao Chou, Marielle E. Yohe, Benjamin Z. Stanton, Bruno Amadio, Ignazio Caruana, Cristiano De Stefanis, Rita De Vito, Franco Locatelli, Yidong Chen, Eleanor Y. Chen, Peter Houghton, Javed Khan, Rossella Rota, Myron S. Ignatius
Nat Commun. 2021; 12: 192. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20386-8
PMCID:
PMC7794422
ArticlePubReaderPDF–5.8MCite
12.
Characterization of genetic lesions in rhabdomyosarcoma using a high‐density single nucleotide polymorphism array
Riki Nishimura, Junko Takita, Aiko Sato‐Otsubo, Motohiro Kato, Katsuyoshi Koh, Ryoji Hanada, Yukichi Tanaka, Keisuke Kato, Daichi Maeda, Masashi Fukayama, Masashi Sanada, Yasuhide Hayashi, Seishi Ogawa
Cancer Sci. 2013 Jul; 104(7): 856–864. Published online 2013 May 23. doi: 10.1111/cas.12173
PMCID:
PMC7657110
ArticlePubReaderPDF–1.8MCite
13.
Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma
Eva Brack, Marco Wachtel, Anja Wolf, Andres Kaech, Urs Ziegler, Beat W. Schäfer
Cell Death Differ. 2020 Aug; 27(8): 2500–2516. Published online 2020 Mar 6. doi: 10.1038/s41418-020-0518-z
PMCID:
PMC7370225
ArticlePubReaderPDF–4.7MCite
14.
Integrative clinical and biopathology analyses to understand the clinical heterogeneity of infantile rhabdomyosarcoma: A report from the French MMT committee
Thibault Butel, Marie Karanian, Gaelle Pierron, Daniel Orbach, Dominique Ranchere, Nathalie Cozic, Louise Galmiche, Aurore Coulomb, Nadège Corradini, Brigitte Lacour, Stéphanie Proust, Florent Guerin, Hélène Boutroux, Angélique Rome, Ludovic Mansuy, Cécile Vérité, Anne‐Sophie Defachelles, Franck Tirode, Veronique Minard‐Colin
Cancer Med. 2020 Apr; 9(8): 2698–2709. Published online 2020 Feb 22. doi: 10.1002/cam4.2713
PMCID:
PMC7163108
ArticlePubReaderPDF–1.5MCite
15.
Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies
Maximilian M. L. Knott, Tilman L. B. Hölting, Shunya Ohmura, Thomas Kirchner, Florencia Cidre-Aranaz, Thomas G. P. Grünewald
Cancer Metastasis Rev. 2019; 38(4): 625–642. Published online 2020 Jan 22. doi: 10.1007/s10555-019-09839-9
PMCID:
PMC6994515
ArticlePubReaderPDF–956KCite
16.
Classification of Rhabdomyosarcoma and Its Molecular Basis
David M. Parham, Frederic G. Barr
Adv Anat Pathol. Author manuscript; available in PMC 2019 Jul 18.
Published in final edited form as: Adv Anat Pathol. 2013 Nov; 20(6): 387–397. doi: 10.1097/PAP.0b013e3182a92d0d
PMCID:
PMC6637949
ArticlePubReaderPDF–6.6MCite
17.
PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines
Simona Camero, Simona Ceccarelli, Francesca De Felice, Francesco Marampon, Olga Mannarino, Lucrezia Camicia, Enrica Vescarelli, Paola Pontecorvi, Barry Pizer, Rajeev Shukla, Amalia Schiavetti, Maria Giovanna Mollace, Antonio Pizzuti, Vincenzo Tombolini, Cinzia Marchese, Francesca Megiorni, Carlo Dominici
J Cancer Res Clin Oncol. 2019; 145(1): 137–152. Published online 2018 Oct 24. doi: 10.1007/s00432-018-2774-6
PMCID:
PMC6326011
ArticlePubReaderPDF–2.6MCite
18.
The transcriptional co-activator TAZ is a potent mediator of alveolar rhabdomyosarcoma tumorigenesis
Michael D. Deel, Katherine K. Slemmons, Ashley R. Hinson, Katia C. Genadry, Breanne A. Burgess, Lisa E.S. Crose, Nina Kuprasertkul, Kristianne M. Oristian, Rex C. Bentley, Corinne M. Linardic
Clin Cancer Res. Author manuscript; available in PMC 2019 Jun 1.
Published in final edited form as: Clin Cancer Res. 2018 Jun 1; 24(11): 2616–2630. Published online 2018 Mar 7. doi: 10.1158/1078-0432.CCR-17-1207
PMCID:
PMC6085878
ArticlePubReaderPDF–1.2MCite
19.
PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
Jason A. Hanna, Matthew R. Garcia, Alicia Lardennois, Patrick J. Leavey, Dino Maglic, Alexandre Fagnan, Jonathan C. Go, Jordan Roach, Yong-Dong Wang, David Finkelstein, Mark E. Hatley
Oncogene. 2018; 37(15): 1991–2007. Published online 2018 Jan 25. doi: 10.1038/s41388-017-0081-3
PMCID:
PMC5895609
ArticlePubReaderPDF–5.0MCite
20.
Clinical and Cytogenetic Profiles of Rhabdomyosarcoma with Bone Marrow Involvement in Korean Children: A 15-Year Single-Institution Experience
Dong-Hyun Lee, Chan-Jeoung Park, Seongsoo Jang, Young-Uk Cho, Jong Jin Seo, Ho Joon Im, Kyung-Nam Koh, Kyung Ja Cho, Joon Seon Song, Eul-Ju Seo
Ann Lab Med. 2018 Mar; 38(2): 132–138. Published online 2017 Dec 4. doi: 10.3343/alm.2018.38.2.132
PMCID:
PMC5736672
ArticlePubReaderPDF–4.1MCite

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