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Select item 66503821.

CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial

D. Max Smith, Kristin W. Weitzel, Amanda R. Elsey, Taimour Langaee, Yan Gong, Dyson T. Wake, Benjamin Q. Duong, Melanie Hagen, Christopher A. Harle, Elvira Mercado, Ying Nagoshi, Kimberly Newsom, Ashleigh Wright, Eric I. Rosenberg, Petr Starostik, Michael J. Clare-Salzler, Siegfried O. Schmidt, Roger B. Fillingim, Julie A. Johnson, Larisa H. Cavallari

Genet Med. Author manuscript; available in PMC 2019 Aug 7.

Published in final edited form as: Genet Med. 2019 Aug; 21(8): 1842–1850. Published online 2019 Jan 23. doi: 10.1038/s41436-018-0431-8

PMCID:: PMC6650382

Abstract Article PDF–579K

Select item 63406192.

The Genetic Variation of CYP2D6 Gene in the Bosnian Population

Hilada Nefic

Med Arch. 2018 Dec; 72(6): 396–400. doi: 10.5455/medarh.2018.72.396-400

PMCID:: PMC6340619

Abstract Article PDF–738K

Select item 63394133.

Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

U. Weissenstein, M. Kunz, M. Oufir, J. T. Wang, M. Hamburger, K. Urech, U. Regueiro, S. Baumgartner

BMC Complement Altern Med. 2019; 19: 23. Published online 2019 Jan 18. doi: 10.1186/s12906-019-2439-2

PMCID:: PMC6339413

Abstract Article PDF–2.4M

Select item 16839164.

The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site.

N Hanioka, S Kimura, U A Meyer, F J Gonzalez

Am J Hum Genet. 1990 Dec; 47(6): 994–1001.

PMCID:: PMC1683916

Summary Page Browse PDF–1.0M

Select item 16830615.

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.

A Gaedigk, M Blum, R Gaedigk, M Eichelbaum, U A Meyer

Am J Hum Genet. 1991 May; 48(5): 943–950.

PMCID:: PMC1683061

Summary Page Browse PDF–1.3M

Select item 66445186.

Biotransformation, Using Recombinant CYP450-Expressing Baker’s Yeast Cells, Identifies a Novel CYP2D6.10^A122V Variant Which Is a Superior Metabolizer of Codeine to Morphine Than the Wild-Type Enzyme

Ibidapo S. Williams, Linda Gatchie, Sandip B. Bharate, Bhabatosh Chaudhuri

ACS Omega. 2018 Aug 31; 3(8): 8903–8912. Published online 2018 Aug 9. doi: 10.1021/acsomega.8b00809

PMCID:: PMC6644518

Abstract Article PDF–1.6M

Select item 65655447.

Genetics and genomic medicine in Sri Lanka

Nirmala D. Sirisena, Vajira H. W. Dissanayake

Mol Genet Genomic Med. 2019 Jun; 7(6): e744. Published online 2019 May 20. doi: 10.1002/mgg3.744

PMCID:: PMC6565544

Abstract Article PDF–769K

Select item 63003668.

Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Barbara Strojny, Ewa Sawosz, Marta Grodzik, Sławomir Jaworski, Jarosław Szczepaniak, Malwina Sosnowska, Mateusz Wierzbicki, Marta Kutwin, Sylwia Orlińska, André Chwalibog

Int J Nanomedicine. 2018; 13: 8561–8575. Published online 2018 Dec 13. doi: 10.2147/IJN.S188997

PMCID:: PMC6300366

Abstract Article PDF–5.0M

Select item 60001029.

基因芯片筛选CD133⁺/CD133^-肺腺癌细胞中新的耐药基因

王红艳, 郑少秋, 涂永生, 张雅洁

Zhongguo Fei Ai Za Zhi. 2014 Jun 20; 17(6): 437–443. Chinese. doi: 10.3779/j.issn.1009-3419.2014.06.01

PMCID:: PMC6000102

Abstract Article PDF–1.4M

Select item 584399710.

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen

Oncol Lett. 2018 Mar; 15(3): 3726–3734. Published online 2018 Jan 16. doi: 10.3892/ol.2018.7808

PMCID:: PMC5843997

Abstract Article PDF–1.5M

Select item 583591011.

Monitoring colorectal cancer following surgery using plasma circulating tumor DNA

Xiao Sun, Tanxiao Huang, Fangsheng Cheng, Kaibing Huang, Ming Liu, Wan He, Mingwei Li, Xiaoni Zhang, Mingyan Xu, Shifu Chen, Ligang Xia

Oncol Lett. 2018 Apr; 15(4): 4365–4375. Published online 2018 Jan 22. doi: 10.3892/ol.2018.7837

PMCID:: PMC5835910

Abstract Article PDF–1.2M

Select item 568708612.

MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation

Linjuan Zeng, Yinting Chen, Yong Wang, Li-Rong Yu, Bridgett Knox, Jiwei Chen, Tieliu Shi, Si Chen, Zhen Ren, Lei Guo, Yuanfeng Wu, David Liu, Kaihong Huang, Weida Tong, Dianke Yu, Baitang Ning

Biochem Pharmacol. Author manuscript; available in PMC 2017 Nov 15.

Published in final edited form as: Biochem Pharmacol. 2017 Sep 15; 140: 139–149. Published online 2017 May 26. doi: 10.1016/j.bcp.2017.05.018