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Select item 68518821.

Hedgehog pathway proteins SMO and GLI expression as prognostic markers in head and neck squamous cell carcinoma

Georg Richtig, Alena M Aigelsreiter, Martin Asslaber, Thomas Weiland, Martin Pichler, Katharina Eberhard, Stephan Sygulla, Silvia Schauer, Gerald Hoefler, Ariane Aigelsreiter

Histopathology. 2019 Jul; 75(1): 118–127. Published online 2019 May 28. doi: 10.1111/his.13860

PMCID:: PMC6851882

Abstract Article PDF–908K

Select item 65704252.

Regulation of GLI1 by cis DNA elements and epigenetic marks

Robert Taylor, Jun Long, Joon Won Yoon, Ronnie Childs, Kathrine B. Sylvestersen, Michael L. Nielsen, King-Fu Leong, Stephen Iannaccone, David O. Walterhouse, David J. Robbins, Philip Iannaccone

DNA Repair (Amst) Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: DNA Repair (Amst). 2019 Jul; 79: 10–21. Published online 2019 May 2. doi: 10.1016/j.dnarep.2019.04.011

PMCID:: PMC6570425

Abstract Article PDF–1.8M

Select item 10159833.

Molecular genetics of neurological tumours.

R Y Chung, B R Seizinger

J Med Genet. 1992 Jun; 29(6): 361–367. doi: 10.1136/jmg.29.6.361

PMCID:: PMC1015983

Summary Page Browse PDF–1.3M

Select item 3635374.

The GLI-Kruppel family of human genes.

J M Ruppert, K W Kinzler, A J Wong, S H Bigner, F T Kao, M L Law, H N Seuanez, S J O'Brien, B Vogelstein

Mol Cell Biol. 1988 Aug; 8(8): 3104–3113. doi: 10.1128/mcb.8.8.3104

PMCID:: PMC363537

Summary Page Browse PDF–2.0M

Select item 68791485.

Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

Alla Piirsoo, Anne Pink, Lagle Kasak, Martin Kala, Sergo Kasvandik, Mart Ustav, Marko Piirsoo

PLoS One. 2019; 14(11): e0225775. Published online 2019 Nov 26. doi: 10.1371/journal.pone.0225775

PMCID:: PMC6879148

Abstract Article PDF–2.2M

Select item 67634956.

The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway

Stefania Scicchitano, Marco Giordano, Valeria Lucchino, Ylenia Montalcini, Emanuela Chiarella, Annamaria Aloisio, Bruna Codispoti, Pietro Zoppoli, Valentina Melocchi, Fabrizio Bianchi, Enrico De Smaele, Maria Mesuraca, Giovanni Morrone, Heather M. Bond

Cell Death Dis. 2019 Oct; 10(10): 715. Published online 2019 Sep 26. doi: 10.1038/s41419-019-1946-x

PMCID:: PMC6763495

Abstract Article PDF–2.1M

Select item 64479557.

Krüppel‐like factor 2 inhibits hepatocarcinogenesis through negative regulation of the Hedgehog pathway

JinBo Lin, Huifang Tan, Yingjie Nie, Dongwen Wu, Weiji Zheng, Wensong Lin, Zheng Zhu, Bing Yang, Xiaoliang Chen, Tao Chen

Cancer Sci. 2019 Apr; 110(4): 1220–1231. Published online 2019 Mar 4. doi: 10.1111/cas.13961

PMCID:: PMC6447955

Abstract Article PDF–1.0M

Select item 61484378.

Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia

Melissa A. Burns, Zi Wei Liao, Natsuko Yamagata, Gayle P. Pouliot, Kristen E. Stevenson, Donna S. Neuberg, Aaron R. Thorner, Matthew Ducar, Emily A. Silverman, Stephen P. Hunger, Mignon L. Loh, Stuart S. Winter, Kimberly P. Dunsmore, Brent Wood, Meenakshi Devidas, Marian H. Harris, Lewis B. Silverman, Stephen E. Sallan, Alejandro Gutierrez

Leukemia. Author manuscript; available in PMC 2018 Oct 5.

Published in final edited form as: Leukemia. 2018 Oct; 32(10): 2126–2137. Published online 2018 Mar 20. doi: 10.1038/s41375-018-0097-x

PMCID:: PMC6148437

Abstract Article PDF–2.0M

Select item 60420239.

Differential Expression of Shh and BMP Signaling in the Potential Conversion of Human Adipose Tissue Stem Cells Into Neuron-Like Cells In Vitro

Alejandra Cardozo, Marcelo Ielpi, Daniel Gómez, Pablo Argibay

Gene Expr. 2010; 14(6): 307–319. Published online 2018 Jul 12. doi: 10.3727/105221610x12717040569866

PMCID:: PMC6042023

Abstract Article PDF–3.2M

Select item 586602910.

Gli family zinc finger 1 is associated with endothelin receptor type B in Hirschsprung disease

Weizhen Liu, Juan Pan, Jinbo Gao, Xiaoming Shuai, Shaotao Tang, Guobin Wang, Kaixiong Tao, Chuanqing Wu

Mol Med Rep. 2018 Apr; 17(4): 5844–5850. Published online 2018 Feb 15. doi: 10.3892/mmr.2018.8612

PMCID:: PMC5866029

Abstract Article PDF–1.3M

Select item 584414011.

Characterization of human dental pulp cells grown in chemically defined serum-free medium

Sakiko Fujii, Katsumi Fujimoto, Noriko Goto, Yoshimitsu Abiko, Asayo Imaoka, Jinchang Shao, Kazuko Kitayama, Masami Kanawa, Agung Sosiawan, Ketut Suardita, Fusanori Nishimura, Yukio Kato

Biomed Rep. 2018 Apr; 8(4): 350–358. Published online 2018 Feb 16. doi: 10.3892/br.2018.1066

PMCID:: PMC5844140

Abstract Article PDF–913K

Select item 572760312.

Inhibition of Gli1-mediated prostate cancer cell proliferation by inhibiting the mTOR/S6K1 signaling pathway

Hong Yang, Libing Hu, Zhimin Liu, Yang Qin, Ruiqian Li, Guoying Zhang, Bin Zhao, Chengwei Bi, Yonghong Lei, Yu Bai

Oncol Lett. 2017 Dec; 14(6): 7970–7976. Published online 2017 Oct 23. doi: 10.3892/ol.2017.7254

PMCID:: PMC5727603

Abstract Article PDF–1.1M

Select item 553842313.

Gli1‐induced deubiquitinase USP48 aids glioblastoma tumorigenesis by stabilizing Gli1

Aidong Zhou, Kangyu Lin, Sicong Zhang, Li Ma, Jianfei Xue, Saint‐Aaron Morris, Kenneth D Aldape, Suyun Huang

EMBO Rep. 2017 Aug; 18(8): 1318–1330. Published online 2017 Jun 16. doi: 10.15252/embr.201643124

PMCID:: PMC5538423

Abstract Article PDF–3.4M

Select item 536496514.

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis

Feng-Tao Shi, Mei Yu, David Zloty, Robert H. Bell, Eddy Wang, Noushin Akhoundsadegh, Gigi Leung, Anne Haegert, Nicholas Carr, Jerry Shapiro, Kevin J. McElwee

Mol Med Rep. 2017 Apr; 15(4): 1441–1454. Published online 2017 Feb 2. doi: 10.3892/mmr.2017.6163

PMCID:: PMC5364965

Abstract Article PDF–1.3M

Select item 528889915.

Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells

DeJie Wang, Guohui Hu, Ying Du, Cheng Zhang, Quqin Lu, Nonghua Lv, Shiwen Luo

J Exp Clin Cancer Res. 2017; 36: 23. Published online 2017 Feb 2. doi: 10.1186/s13046-017-0491-7

PMCID:: PMC5288899

Abstract Article PDF–4.1M

Select item 508698816.

Notch3 drives development and progression of cholangiocarcinoma

Rachel V. Guest, Luke Boulter, Benjamin J. Dwyer, Timothy J. Kendall, Tak-Yung Man, Sarah E. Minnis-Lyons, Wei-Yu Lu, Andrew J. Robson, Sofia Ferreira Gonzalez, Alexander Raven, Davina Wojtacha, Jennifer P. Morton, Mina Komuta, Tania Roskams, Stephen J. Wigmore, Owen J. Sansom, Stuart J. Forbes

Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12250–12255. Published online 2016 Oct 10. doi: 10.1073/pnas.1600067113

PMCID:: PMC5086988

Abstract Article PDF–1.5M

Select item 468612217.

Detection and preliminary screening of the human gene expression profile for Hirschsprung's disease

XIN WANG, SHIQI WANG, XIANQING JIN, NING WANG, YUANYUAN LUO, YINPING TENG

Mol Med Rep. 2016 Jan; 13(1): 641–650. Published online 2015 Dec 1. doi: 10.3892/mmr.2015.4633

PMCID:: PMC4686122

Abstract Article PDF–1.1M

Select item 413805318.

The sonic hedgehog factor Gli1 imparts drug resistance through inducible glucuronidation

Hiba Ahmad Zahreddine, Biljana Culjkovic-Kraljacic, Sarit Assouline, Patrick Gendron, Andrea A. Romeo, Stephen J. Morris, Gregory Cormack, James B. Jaquith, Leandro Cerchietti, Eftihia Cocolakis, Abdellatif Amri, Julie Bergeron, Brian Leber, Michael W. Becker, Shanshan Pei, Craig T. Jordan, Wilson H. Miller, Jr, Katherine L.B. Borden

Nature. Author manuscript; available in PMC 2015 Jan 3.

Published in final edited form as: Nature. 2014 Jul 3; 511(7507): 90–93. Published online 2014 May 28. doi: 10.1038/nature13283

PMCID:: PMC4138053

Article PDF–2.8M

Select item 405866519.

Molecular Determinants of the Response of Tumor Cells to Boswellic Acids

Tolga Eichhorn, Henry Johannes Greten, Thomas Efferth

Pharmaceuticals (Basel) 2011 Aug; 4(8): 1171–1182. Published online 2011 Aug 19. doi: 10.3390/ph4081171

PMCID:: PMC4058665

Abstract Article PDF–574K

Select item 392281420.

Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling

Qi Chen, Rong Xu, Chunyan Zeng, Quqin Lu, Dengliang Huang, Chao Shi, Weilong Zhang, Libin Deng, Runwei Yan, Hai Rao, Guolan Gao, Shiwen Luo

PLoS One. 2014; 9(2): e88386. Published online 2014 Feb 12. doi: 10.1371/journal.pone.0088386

PMCID:: PMC3922814

Abstract Article PDF–2.4M

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