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Select item 67551661.

Niacin regulates apolipoprotein M expression via liver X receptor-α

Liu Yang, Tie Li, Shuiping Zhao, Saidan Zhang

Mol Med Rep. 2019 Oct; 20(4): 3285–3291. Published online 2019 Aug 6. doi: 10.3892/mmr.2019.10557

PMCID:: PMC6755166

Abstract Article PDF–522K

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 64218103.

The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism

Hyoun-Ah Kim, Wook-Young Baek, Mi-Hwa Han, Ju-Yang Jung, Chang-Hee Suh

Mediators Inflamm. 2019; 2019: 6217548. Published online 2019 Feb 28. doi: 10.1155/2019/6217548

PMCID:: PMC6421810

Abstract Article PDF–2.6M

Select item 67204934.

Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?

Kevin Mouzat, Aleksandra Chudinova, Anne Polge, Jovana Kantar, William Camu, Cédric Raoul, Serge Lumbroso

Int J Mol Sci. 2019 Aug; 20(16): 3858. Published online 2019 Aug 8. doi: 10.3390/ijms20163858

PMCID:: PMC6720493

Abstract Article PDF–1004K

Select item 60420195.

Gene Expression Variability in Subcutaneous and Omental Adipose Tissue of Obese Men

Yonghua Zhang, Yohan Bossé, Picard Marceau, Simon Biron, Stephan Lebel, Denis Richard, Marie-Claude Vohl, André Tchernof

Gene Expr. 2007; 14(1): 35–46. Published online 2018 Jul 12. doi: 10.3727/000000007783991772

PMCID:: PMC6042019

Abstract Article PDF–107K

Select item 53602726.

Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells

Girish C. Mohan, Huayi Zhang, Lei Bao, Benjamin Many, Lawrence S. Chan

PLoS One. 2017; 12(3): e0173981. Published online 2017 Mar 21. doi: 10.1371/journal.pone.0173981

PMCID:: PMC5360272

Abstract Article PDF–1.9M

Select item 53566827.

Small heterodimer partner 1 directly interacts with NS5A viral protein and has a key role in HCV related liver cell transformation

Beatrice Conti, Cristiana Porcu, Carmela Viscomi, Antonella Minutolo, Susan Costantini, Marco Corazzari, Gino Iannucci, Barbara Barbaro, Clara Balsano

Oncotarget. 2016 Dec 20; 7(51): 84575–84586. Published online 2016 Sep 20. doi: 10.18632/oncotarget.12144

PMCID:: PMC5356682

Abstract Article PDF–3.0M

Select item 45672358.

Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells

Chunyang Du, Yonghong Shi, Yunzhuo Ren, Haijiang Wu, Fang Yao, Jinying Wei, Ming Wu, Yanjuan Hou, Huijun Duan

Drug Des Devel Ther. 2015; 9: 5099–5113. Published online 2015 Sep 4. doi: 10.2147/DDDT.S90201

PMCID:: PMC4567235

Abstract Article PDF–2.0M

Select item 43632869.

Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL

Jung Wha Lee, Jiahn-Dar Huang, Ignacio R. Rodriguez

Biochim Biophys Acta. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Biochim Biophys Acta. 2015 May; 1851(5): 605–619. Published online 2015 Jan 22. doi: 10.1016/j.bbalip.2015.01.007

PMCID:: PMC4363286

Abstract Article PDF–7.0M

Select item 433320910.

Patterns of Gene Transcript Abundance in the Blood of Children with Severe or Uncomplicated Dengue Highlight Differences in Disease Evolution and Host Response to Dengue Virus Infection

Hoang Truong Long, Martin L. Hibberd, Tran Tinh Hien, Nguyen Minh Dung, Tran Van Ngoc, Jeremy Farrar, Bridget Wills, Cameron P. Simmons

J Infect Dis. Author manuscript; available in PMC 2015 Feb 19.

Published in final edited form as: J Infect Dis. 2009 Feb 15; 199(4): 537–546. doi: 10.1086/596507

PMCID:: PMC4333209

Abstract Article PDF–1.9M

Select item 400717911.

Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin

Zuo-quan Xie, Gai Liang, Lu Zhang, Qi Wang, Yi Qu, Yang Gao, Li-bo Lin, Sai Ye, Ji Zhang, Hui Wang, Guo-ping Zhao, Qing-hua Zhang

Acta Pharmacol Sin. 2009 Sep; 30(9): 1262–1275. Published online 2009 Aug 24. doi: 10.1038/aps.2009.126

PMCID:: PMC4007179

Abstract Article PDF–2.0M

Select item 362232112.

High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway

Bin Dong, Chin Fung Kelvin Kan, Amar B. Singh, Jingwen Liu

J Lipid Res. 2013 May; 54(5): 1241–1254. doi: 10.1194/jlr.M032599

PMCID:: PMC3622321

Abstract Article PDF–1.5M

Select item 332939313.

Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells

Lin-Hua Zhang, Vaijinath S. Kamanna, Shobha H. Ganji, Xi-Ming Xiong, Moti L. Kashyap

J Lipid Res. 2012 May; 53(5): 941–950. doi: 10.1194/jlr.M020917

PMCID:: PMC3329393

Abstract Article PDF–1.0M

Select item 323504014.

Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

Anne G Lundemo, Caroline HH Pettersen, Kjetil Berge, Rolf K Berge, Svanhild A Schønberg

Lipids Health Dis. 2011; 10: 190. Published online 2011 Oct 25. doi: 10.1186/1476-511X-10-190

PMCID:: PMC3235040

Abstract Article PDF–1.7M

Select item 282115815.

Profiling of zinc altered gene expression in human prostate normal versus cancer cells: a time course study

Shu-fei Lin, Hua Wei, Dennis Maeder, Renty B. Franklin, Pei Feng

J Nutr Biochem. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: J Nutr Biochem. 2009 Dec; 20(12): 1000. Published online 2008 Dec 13. doi: 10.1016/j.jnutbio.2008.09.004

PMCID:: PMC2821158

Abstract Article PDF–333K

Select item 275332416.

Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells

Audun O Vik-Mo, Johan Fernø, Silje Skrede, Vidar M Steen

BMC Pharmacol. 2009; 9: 10. Published online 2009 Aug 29. doi: 10.1186/1471-2210-9-10

PMCID:: PMC2753324

Abstract Article PDF–837K

Select item 270722817.

Ceramide Stimulates ABCA12 Expression via Peroxisome Proliferator-activated Receptor δ in Human Keratinocytes

Yan J. Jiang, Yoshikazu Uchida, Biao Lu, Peggy Kim, Cungui Mao, Masashi Akiyama, Peter M. Elias, Walter M. Holleran, Carl Grunfeld, Kenneth R. Feingold

J Biol Chem. 2009 Jul 10; 284(28): 18942–18952. Published online 2009 May 8. doi: 10.1074/jbc.M109.006973