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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 66606442.

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures

Kornelia Ellwanger, Selina Briese, Christine Arnold, Ioannis Kienes, Valentin Heim, Ueli Nachbur, Thomas A Kufer

Life Sci Alliance. 2019 Aug; 2(4): e201900346. Published online 2019 Jul 26. doi: 10.26508/lsa.201900346

PMCID:: PMC6660644

Abstract Article PDF–2.7M

Select item 62557603.

Structural basis of RIP2 activation and signaling

Qin Gong, Ziqi Long, Franklin L. Zhong, Daniel Eng Thiam Teo, Yibo Jin, Zhan Yin, Zhao Zhi Boo, Yaming Zhang, Jiawen Zhang, Renliang Yang, Shashi Bhushan, Bruno Reversade, Zongli Li, Bin Wu

Nat Commun. 2018; 9: 4993. Published online 2018 Nov 26. doi: 10.1038/s41467-018-07447-9

PMCID:: PMC6255760

Abstract Article PDF–3.0M

Select item 59921764.

Pyrimidine synthesis inhibition enhances cutaneous defenses against antibiotic resistant bacteria through activation of NOD2 signaling

Samreen Jatana, Craig R. Homer, Maria Madajka, András K. Ponti, Amrita Kabi, Francis Papay, Christine McDonald

Sci Rep. 2018; 8: 8708. Published online 2018 Jun 7. doi: 10.1038/s41598-018-27012-0

PMCID:: PMC5992176

Abstract Article PDF–2.8M

Select item 57777995.

Anti-tumor efficacy of oncolytic reovirus against gastrointestinal stromal tumor cells

Yusuke Inagaki, Eiji Kubota, Yoshinori Mori, Mineyoshi Aoyama, Hiromi Kataoka, Randal N. Johnston, Takashi Joh

Oncotarget. 2017 Dec 29; 8(70): 115632–115646. Published online 2017 Dec 18. doi: 10.18632/oncotarget.23361

PMCID:: PMC5777799

Abstract Article PDF–8.9M

Select item 45462806.

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2

Roland N. Wagner, John C. Reed, Sumit K. Chanda

Retrovirology. 2015; 12: 74. Published online 2015 Aug 22. doi: 10.1186/s12977-015-0200-6

PMCID:: PMC4546280

Abstract Article PDF–1.4M

Select item 43319717.

Differential Expression of Gene Profiles in MRGX-treated Lung Cancer

Yong-Kyun Kwon, Seung-Yeul Lee, Hwan-Soo Kang, Jung-Suk Sung, Chong-Kwan Cho, Hwa-Seung Yoo, Seungjin Shin, Jong-Soon Choi, Yeon-Weol Lee, Ik-Soon Jang

J Pharmacopuncture. 2013 Sep; 16(3): 30–38. doi: 10.3831/KPI.2013.16.018

PMCID:: PMC4331971

Abstract Article PDF–971K

Select item 43225588.

A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation

Angela Burleigh, Steven McKinney, Jazmine Brimhall, Damian Yap, Peter Eirew, Steven Poon, Viola Ng, Adrian Wan, Leah Prentice, Lois Annab, J Carl Barrett, Carlos Caldas, Connie Eaves, Samuel Aparicio

Breast Cancer Res. 2015; 17: 4. Published online 2015 Jan 9. doi: 10.1186/s13058-014-0510-y

PMCID:: PMC4322558

Abstract Article PDF–3.9M

Select item 42942609.

Transcriptomic and Proteomic Analyses Reveal Key Innate Immune Signatures in the Host Response to the Gastrointestinal Pathogen Campylobacter concisus

Nadeem O. Kaakoush, Nandan P. Deshpande, Si Ming Man, Jose A. Burgos-Portugal, Faisal A. Khattak, Mark J. Raftery, Marc R. Wilkins, Hazel M. Mitchell

Infect Immun. 2015 Feb; 83(2): 832–845. Prepublished online 2014 Dec 8. Published online 2015 Jan 14. doi: 10.1128/IAI.03012-14

PMCID:: PMC4294260

Abstract Article PDF–2.1M

Select item 426412610.

X-ray-Induced Changes in the Expression of Inflammation-Related Genes in Human Peripheral Blood

Ping Wang, Fei Guo, Lin Han, Xi’ai Wang, Jie Li, Yan Guo, Yumin LÜ

Int J Mol Sci. 2014 Nov; 15(11): 19516–19534. Published online 2014 Oct 27. doi: 10.3390/ijms151119516

PMCID:: PMC4264126

Abstract Article PDF–1.6M

Select item 395320311.

NOD2/RICK-Dependent β-Defensin 2 Regulation Is Protective for Nontypeable Haemophilus influenzae-Induced Middle Ear Infection

Jeong-Im Woo, Sejo Oh, Paul Webster, Yoo Jin Lee, David J. Lim, Sung K. Moon

PLoS One. 2014; 9(3): e90933. Published online 2014 Mar 13. doi: 10.1371/journal.pone.0090933

PMCID:: PMC3953203

Abstract Article PDF–3.6M

Select item 358489912.

Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients

Mercè Giner, Mª José Montoya, Mª Angeles Vázquez, Cristina Miranda, Ramón Pérez-Cano

BMC Musculoskelet Disord. 2013; 14: 41. Published online 2013 Jan 25. doi: 10.1186/1471-2474-14-41

PMCID:: PMC3584899

Abstract Article PDF–273K

Select item 344073513.

Identification of novel molecular markers for detection of gastric cancer cells in the peripheral blood circulation using genome-wide microarray analysis

NOBUYUKI MATSUMURA, HITOSHI ZEMBUTSU, KOJI YAMAGUCHI, KAZUAKI SASAKI, TETSUHIRO TSURUMA, TOSHIHIKO NISHIDATE, RYUICHI DENNO, KOICHI HIRATA

Exp Ther Med. 2011 Jul-Aug; 2(4): 705–713. Published online 2011 Apr 8. doi: 10.3892/etm.2011.252

PMCID:: PMC3440735

Abstract Article PDF–302K

Select item 340814114.

A Dual Role for Receptor-interacting Protein Kinase 2 (RIP2) Kinase Activity in Nucleotide-binding Oligomerization Domain 2 (NOD2)-dependent Autophagy

Craig R. Homer, Amrita Kabi, Noemí Marina-García, Arun Sreekumar, Alexey I. Nesvizhskii, Kourtney P. Nickerson, Arul M. Chinnaiyan, Gabriel Nuñez, Christine McDonald

J Biol Chem. 2012 Jul 20; 287(30): 25565–25576. Published online 2012 Jun 4. doi: 10.1074/jbc.M111.326835

PMCID:: PMC3408141

Abstract Article PDF–2.2M

Select item 316993615.

A network biology approach evaluating the anticancer effects of bortezomib identifies SPARC as a therapeutic target in adult T-cell leukemia cells

Junko H Ohyashiki, Ryoko Hamamura, Chiaki Kobayashi, Yu Zhang, Kazuma Ohyashiki

Adv Appl Bioinforma Chem. 2008; 1: 85–98. Published online 2008 Oct 30. doi: 10.2147/aabc.s4133

PMCID:: PMC3169936

Abstract Article PDF–1.6M

Select item 312783716.

HPV16 E2 could act as down-regulator in cellular genes implicated in apoptosis, proliferation and cell differentiation

Eric Ramírez-Salazar, Federico Centeno, Karen Nieto, Armando Valencia-Hernández, Mauricio Salcedo, Efraín Garrido

Virol J. 2011; 8: 247. Published online 2011 May 20. doi: 10.1186/1743-422X-8-247

PMCID:: PMC3127837

Abstract Article PDF–362K

Select item 288217317.

Hypoxia inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

Hsin-Yu Fang, Russell Hughes, Craig Murdoch, Seth Coffelt, Subhra K. Biswas, Adrian L. Harris, Randall S. Johnson, Hongxia Z. Imityaz, M. Celeste Simon, Erik Fredlund, Florian Greten, Jordi Rius, Claire E. Lewis

Blood. Author manuscript; available in PMC 2010 Jun 8.

Published in final edited form as: Blood. 2009 Jul 23; 114(4): 844–859. Published online 2009 May 19. doi: 10.1182/blood-2008-12-195941