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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 64232782.

Network-based prediction of protein interactions

István A. Kovács, Katja Luck, Kerstin Spirohn, Yang Wang, Carl Pollis, Sadie Schlabach, Wenting Bian, Dae-Kyum Kim, Nishka Kishore, Tong Hao, Michael A. Calderwood, Marc Vidal, Albert-László Barabási

Nat Commun. 2019; 10: 1240. Published online 2019 Mar 18. doi: 10.1038/s41467-019-09177-y

PMCID:: PMC6423278

Abstract Article PDF–1.1M

Select item 63338943.

Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule–kinetochore attachment

Gangyin Zhao, Yubao Cheng, Ping Gui, Meiying Cui, Wei Liu, Wenwen Wang, Xueying Wang, Mahboob Ali, Zhen Dou, Liwen Niu, Haiyan Liu, Leonard Anderson, Ke Ruan, Jingjun Hong, Xuebiao Yao

J Biol Chem. 2019 Jan 11; 294(2): 576–592. Published online 2018 Nov 8. doi: 10.1074/jbc.RA118.003844

PMCID:: PMC6333894

Abstract Article PDF–5.5M

Select item 62879474.

Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

Claudia Pellacani, Elisabetta Bucciarelli, Fioranna Renda, Daniel Hayward, Antonella Palena, Jack Chen, Silvia Bonaccorsi, James G Wakefield, Maurizio Gatti, Maria Patrizia Somma

eLife. 2018; 7: e40325. Published online 2018 Nov 26. doi: 10.7554/eLife.40325

PMCID:: PMC6287947

Abstract Article PDF–8.6M

Select item 2324545.

HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis.

Y Chen, D J Riley, P L Chen, W H Lee

Mol Cell Biol. 1997 Oct; 17(10): 6049–6056. doi: 10.1128/mcb.17.10.6049

PMCID:: PMC232454

Summary PDF–952K

Select item 856456.

Retinoblastoma Protein Enhances the Fidelity of Chromosome Segregation Mediated by hsHec1p

Lei Zheng, Yumay Chen, Daniel J. Riley, Phang-Lang Chen, Wen-Hwa Lee

Mol Cell Biol. 2000 May; 20(10): 3529–3537. doi: 10.1128/mcb.20.10.3529-3537.2000

PMCID:: PMC85645

Abstract Article PDF–1.4M

Select item 843847.

Hec1p, an Evolutionarily Conserved Coiled-Coil Protein, Modulates Chromosome Segregation through Interaction with SMC Proteins

Lei Zheng, Yumay Chen, Wen-Hwa Lee

Mol Cell Biol. 1999 Aug; 19(8): 5417–5428. doi: 10.1128/mcb.19.8.5417

PMCID:: PMC84384

Abstract Article PDF–1.6M

Select item 68839558.

Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinoma

Haiping Zhang, Jian Zou, Ying Yin, Bo Zhang, Yaling Hu, Jingjing Wang, Huijun Mu

PeerJ. 2019; 7: e8096. Published online 2019 Nov 26. doi: 10.7717/peerj.8096

PMCID:: PMC6883955

Abstract Article PDF–9.0M

Select item 53411229.

Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly

Paraskevi Sgourdou, Ketu Mishra-Gorur, Ichiko Saotome, Octavian Henagariu, Beyhan Tuysuz, Cynthia Campos, Keiko Ishigame, Krinio Giannikou, Jennifer L. Quon, Nenad Sestan, Ahmet O. Caglayan, Murat Gunel, Angeliki Louvi

Sci Rep. 2017; 7: 43708. Published online 2017 Mar 8. doi: 10.1038/srep43708

PMCID:: PMC5341122

Abstract Article PDF–3.4M

Select item 510088010.

Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer

Zbynek Heger, Miguel Angel Merlos Rodrigo, Petr Michalek, Hana Polanska, Michal Masarik, Vitezslav Vit, Mariana Plevova, Dalibor Pacik, Tomas Eckschlager, Marie Stiborova, Vojtech Adam

PLoS One. 2016; 11(11): e0165830. Published online 2016 Nov 8. doi: 10.1371/journal.pone.0165830

Retraction in:: PLoS One. 2022; 17(5): e0268981.

PMCID:: PMC5100880

Abstract Article

Select item 495731111.

Breakpoints and deleted genes identification of ring chromosome 18 in a Chinese girl by whole-genome low-coverage sequencing: a case report study

Hui Yao, Chuanchun Yang, Xiaoli Huang, Luhong Yang, Wei Zhao, Dan Yin, Yuan Qin, Feng Mu, Lin Liu, Ping Tian, Zhisheng Liu, Yun Yang

BMC Med Genet. 2016; 17: 49. Published online 2016 Jul 22. doi: 10.1186/s12881-016-0307-1

PMCID:: PMC4957311

Abstract Article PDF–1.8M

Select item 443895712.

cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro

TE-CHUN HSIA, CHIEN-CHIH YU, SHU-CHUN HSU, NOU-YING TANG, HSU-FENG LU, CHUN-SHU YU, SHIN-HWAR WU, JAUNG-GENG LIN, JING-GUNG CHUNG

Mol Med Rep. 2015 Jul; 12(1): 1030–1042. Published online 2015 Mar 24. doi: 10.3892/mmr.2015.3538

PMCID:: PMC4438957

Abstract Article PDF–1.0M

Select item 433320913.

Patterns of Gene Transcript Abundance in the Blood of Children with Severe or Uncomplicated Dengue Highlight Differences in Disease Evolution and Host Response to Dengue Virus Infection

Hoang Truong Long, Martin L. Hibberd, Tran Tinh Hien, Nguyen Minh Dung, Tran Van Ngoc, Jeremy Farrar, Bridget Wills, Cameron P. Simmons

J Infect Dis. Author manuscript; available in PMC 2015 Feb 19.

Published in final edited form as: J Infect Dis. 2009 Feb 15; 199(4): 537–546. doi: 10.1086/596507

PMCID:: PMC4333209

Abstract Article PDF–1.9M

Select item 405192414.

Role of the Na⁺/K⁺/2Cl^- cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma

Atsushi Shiozaki, Yoshito Nako, Daisuke Ichikawa, Hirotaka Konishi, Shuhei Komatsu, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Yoshinori Marunaka, Eigo Otsuji

World J Gastroenterol. 2014 Jun 14; 20(22): 6844–6859. Published online 2014 Jun 14. doi: 10.3748/wjg.v20.i22.6844

PMCID:: PMC4051924

Abstract Article PDF–1.6M

Select item 400279015.

Inhibition of Hec1 expression enhances the sensitivity of human ovarian cancer cells to paclitaxel

Qing-qing Mo, Ping-bo Chen, Xin Jin, Qian Chen, Lan Tang, Bei-bei Wang, Ke-zhen Li, Peng Wu, Yong Fang, Shi-xuan Wang, Jian-feng Zhou, Ding Ma, Gang Chen

Acta Pharmacol Sin. 2013 Apr; 34(4): 541–548. Published online 2013 Mar 11. doi: 10.1038/aps.2012.197

PMCID:: PMC4002790

Abstract Article PDF–3.6M

Select item 369802116.

Regulation of protumorigenic pathways by Insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis

Priyanka Sehgal, Neeraj Kumar, Varuvar Rajesh Praveen Kumar, Shilpa Patil, Animesh Bhattacharya, Manavalan Vijaya Kumar, Geetashree Mukherjee, Paturu Kondaiah

Mol Cancer. 2013; 12: 63. Published online 2013 Jun 16. doi: 10.1186/1476-4598-12-63