PMC Links for Nucleotide (Select 1519313202) - PMC

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 60070802.

Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence

Kendra S. Plafker, Katarzyna Zyla, William Berry, Scott M. Plafker

Redox Biol. 2018 Jul; 17: 411–422. Published online 2018 May 21. doi: 10.1016/j.redox.2018.05.008

PMCID:: PMC6007080

Abstract Article PDF–3.2M

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 47091364.

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

Carsten C. Scholz, Javier Rodriguez, Christina Pickel, Stephen Burr, Jacqueline-alba Fabrizio, Karen A. Nolan, Patrick Spielmann, Miguel A. S. Cavadas, Bianca Crifo, Doug N. Halligan, James A. Nathan, Daniel J. Peet, Roland H. Wenger, Alex Von Kriegsheim, Eoin P. Cummins, Cormac T. Taylor

PLoS Biol. 2016 Jan; 14(1): e1002347. Published online 2016 Jan 11. doi: 10.1371/journal.pbio.1002347

PMCID:: PMC4709136

Abstract Article PDF–2.3M

Select item 42946795.

The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2

Kendra S. Plafker, Scott M. Plafker

Mol Biol Cell. 2015 Jan 15; 26(2): 327–338. doi: 10.1091/mbc.E14-06-1057

PMCID:: PMC4294679

Abstract Article PDF–4.5M

Select item 16926676.

Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha.

R T Hay, L Vuillard, J M Desterro, M S Rodriguez

Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29; 354(1389): 1601–1609. doi: 10.1098/rstb.1999.0504

PMCID:: PMC1692667

Summary PDF–183K

Select item 54550997.

Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes

Xinliang Zhao, Xiaoyan Dong, Xiucui Luo, Jing Pan, Weina Ju, Meijiao Zhang, Peirong Wang, Mei Zhong, Yanhong Yu, W. Ted Brown, Nanbert Zhong

Front Pharmacol. 2017; 8: 310. Published online 2017 Jun 2. doi: 10.3389/fphar.2017.00310

PMCID:: PMC5455099

Abstract Article PDF–1.4M

Select item 35341068.

Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB

Deok-Soo Son, Syder M. Kabir, Yuan-Lin Dong, Eunsook Lee, Samuel E. Adunyah

PLoS One. 2012; 7(12): e51116. Published online 2012 Dec 31. doi: 10.1371/journal.pone.0051116

PMCID:: PMC3534106

Abstract Article PDF–2.2M

Select item 35287439.

In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data

Qi Liu, Han Zhou, Kui Zhang, Xiaoxiao Shi, Wei Fan, Ruixin Zhu, Philip S. Yu, Zhiwei Cao

PLoS One. 2012; 7(12): e50697. Published online 2012 Dec 21. doi: 10.1371/journal.pone.0050697

PMCID:: PMC3528743

Abstract Article PDF–1.0M

Select item 341296510.

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

Yi Sheng, Jenny H. Hong, Ryan Doherty, Tharan Srikumar, Jonathan Shloush, George V. Avvakumov, John R. Walker, Sheng Xue, Dante Neculai, Janet W. Wan, Sung K. Kim, Cheryl H. Arrowsmith, Brian Raught, Sirano Dhe-Paganon

Mol Cell Proteomics. 2012 Aug; 11(8): 329–341. Published online 2012 Apr 10. doi: 10.1074/mcp.O111.013706

PMCID:: PMC3412965

Abstract Article PDF–2.4M

Select item 334976311.

Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients

Angela L. Rasmussen, Nicolas Tchitchek, Nathan J. Susnow, Alexei L. Krasnoselsky, Deborah L. Diamond, Matthew M. Yeh, Sean C. Proll, Marcus J. Korth, Kathie-Anne Walters, Sharon Lederer, Anne M. Larson, Robert L. Carithers, Arndt Benecke, Michael G. Katze

Hepatology. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Hepatology. 2012 Jul; 56(1): 17–27. Published online 2012 Jun 5. doi: 10.1002/hep.25612