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Select item 64478351.

Frizzled 2‐induced epithelial‐mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma

Huohui Ou, Zhanjun Chen, Leyang Xiang, Yinghao Fang, Yuyan Xu, Qin Liu, Zhigang Hu, Xianghong Li, Yu Huang, Dinghua Yang

Cancer Sci. 2019 Apr; 110(4): 1169–1182. Published online 2019 Mar 6. doi: 10.1111/cas.13949

PMCID:: PMC6447835

Abstract Article PDF–1.7M

Select item 62314992.

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

Peng Chen, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-ho Lam, Zheng Liu, Xi He, Kay Perry, Min Dong, Rongsheng Jin

Science. Author manuscript; available in PMC 2019 May 11.

Published in final edited form as: Science. 2018 May 11; 360(6389): 664–669. doi: 10.1126/science.aar1999

PMCID:: PMC6231499

Abstract Article PDF–2.3M

Select item 57252913.

Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway

Bo Qi, Yan Wang, Zhi-Jun Chen, Xiang-Nan Li, Yu Qi, Yang Yang, Guang-Hui Cui, Hai-Zhou Guo, Wei-Hao Li, Song Zhao

World J Gastroenterol. 2017 Dec 7; 23(45): 7965–7977. Published online 2017 Dec 7. doi: 10.3748/wjg.v23.i45.7965

PMCID:: PMC5725291

Abstract Article PDF–1.5M

Select item 22544344.

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

Changgong Li, Hongyan Chen, Lingyan Hu, Yiming Xing, Tomoyo Sasaki, Maria F Villosis, John Li, Michiru Nishita, Yasuhiro Minami, Parviz Minoo

BMC Mol Biol. 2008; 9: 11. Published online 2008 Jan 23. doi: 10.1186/1471-2199-9-11

PMCID:: PMC2254434

Abstract Article PDF–537K

Select item 214795.

A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals

Shinji Tanaka, Tsuyoshi Akiyoshi, Masaki Mori, Jack R. Wands, Keizo Sugimachi

Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17): 10164–10169. doi: 10.1073/pnas.95.17.10164

PMCID:: PMC21479

Abstract Article PDF–435K

Select item 64043356.

In-depth characterization of the Wnt-signaling/β-catenin pathway in an in vitro model of Barrett’s sequence

Katharina Götzel, Olga Chemnitzer, Luisa Maurer, Arne Dietrich, Uwe Eichfeld, Orestis Lyros, Yusef Moulla, Stefan Niebisch, Matthias Mehdorn, Boris Jansen-Winkeln, Michael Vieth, Albrecht Hoffmeister, Ines Gockel, René Thieme

BMC Gastroenterol. 2019; 19: 38. Published online 2019 Mar 6. doi: 10.1186/s12876-019-0957-5

PMCID:: PMC6404335

Abstract Article PDF–2.3M

Select item 63946757.

Genes responsible for proliferation, differentiation, and junction adhesion are significantly up-regulated in human ovarian granulosa cells during a long-term primary in vitro culture

Wiesława Kranc, Maciej Brązert, Joanna Budna, Piotr Celichowski, Artur Bryja, Mariusz J. Nawrocki, Katarzyna Ożegowska, Maurycy Jankowski, Błażej Chermuła, Marta Dyszkiewicz-Konwińska, Michal Jeseta, Leszek Pawelczyk, Andrzej Bręborowicz, Dominik Rachoń, Małgorzata Bruska, Michał Nowicki, Maciej Zabel, Bartosz Kempisty

Histochem Cell Biol. 2019; 151(2): 125–143. Published online 2018 Oct 31. doi: 10.1007/s00418-018-1750-1

PMCID:: PMC6394675

Abstract Article PDF–6.5M

Select item 63012568.

Detection and Analysis of the Hedgehog Signaling Pathway-Related Long Non-Coding RNA (lncRNA) Expression Profiles in Keloid

Heping Huang, Shangfeng Fu, Dewu Liu

Med Sci Monit. 2018; 24: 9032–9044. Published online 2018 Dec 13. doi: 10.12659/MSM.911159

PMCID:: PMC6301256

Abstract Article PDF–909K

Select item 51665719.

Exome sequencing in a consanguineous family clinically diagnosed with early onset Alzheimer’s disease identifies an homozygous CTSF mutation

Jose Bras, Ruth Djaldetti, Ana Margarida Alves, Simon Mead, Lee Darwent, Alberto Lleo, Jose Luis Molinuevo, Rafael Blesa, Andrew Singleton, John Hardy, Jordi Clarimon, Rita Guerreiro

Neurobiol Aging. Author manuscript; available in PMC 2016 Dec 19.

Published in final edited form as: Neurobiol Aging. 2016 Oct; 46: 236.e1–236.e6. Published online 2016 Jul 4. doi: 10.1016/j.neurobiolaging.2016.06.018

PMCID:: PMC5166571

Abstract Article PDF–1014K

Select item 508698810.

Notch3 drives development and progression of cholangiocarcinoma

Rachel V. Guest, Luke Boulter, Benjamin J. Dwyer, Timothy J. Kendall, Tak-Yung Man, Sarah E. Minnis-Lyons, Wei-Yu Lu, Andrew J. Robson, Sofia Ferreira Gonzalez, Alexander Raven, Davina Wojtacha, Jennifer P. Morton, Mina Komuta, Tania Roskams, Stephen J. Wigmore, Owen J. Sansom, Stuart J. Forbes

Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12250–12255. Published online 2016 Oct 10. doi: 10.1073/pnas.1600067113

PMCID:: PMC5086988

Abstract Article PDF–1.5M

Select item 440842811.

Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy

Suzanne F.C. Miller-Delaney, Kenneth Bryan, Sudipto Das, Ross C. McKiernan, Isabella M. Bray, James P. Reynolds, Ryder Gwinn, Raymond L. Stallings, David C. Henshall

Brain. 2015 Mar; 138(3): 616–631. Published online 2014 Dec 31. doi: 10.1093/brain/awu373

PMCID:: PMC4408428

Abstract Article PDF–1.3M

Select item 432255812.

A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation

Angela Burleigh, Steven McKinney, Jazmine Brimhall, Damian Yap, Peter Eirew, Steven Poon, Viola Ng, Adrian Wan, Leah Prentice, Lois Annab, J Carl Barrett, Carlos Caldas, Connie Eaves, Samuel Aparicio

Breast Cancer Res. 2015; 17: 4. Published online 2015 Jan 9. doi: 10.1186/s13058-014-0510-y

PMCID:: PMC4322558

Abstract Article PDF–3.9M

Select item 415623113.

Short hairpin RNA of frizzled-2 suppresses the proliferation of hepatocellular carcinoma cells

MINORU TOMIZAWA, FUMINOBU SHINOZAKI, YASUFUMI MOTOYOSHI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO, MAKOTO SUEISHI

Oncol Lett. 2014 Oct; 8(4): 1519–1522. Published online 2014 Aug 4. doi: 10.3892/ol.2014.2408

PMCID:: PMC4156231

Abstract Article PDF–502K

Select item 386156614.

Frizzled-2: A potential novel target for molecular pancreatic cancer therapy

MINORU TOMIZAWA, FUMINOBU SHINOZAKI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO, MAKOTO SUEISHI, TAKANOBU YOSHIDA

Oncol Lett. 2014 Jan; 7(1): 74–78. Published online 2013 Nov 12. doi: 10.3892/ol.2013.1681

PMCID:: PMC3861566

Abstract Article PDF–543K

Select item 358987915.

Differential Expression of Wnt Pathway Genes in Sporadic Hepatocellular Carcinomas Infected With Hepatitis B Virus Identified With OligoGE Arrays

Xiaoyan Lin, Qiangxiu Wang, Zhixin Cao, Ming Geng, Yongcheng Cao, Xiaohong Liu

Hepat Mon. 2013 Jan; 13(1): e6192. Published online 2013 Jan 23. doi: 10.5812/hepatmon.6192

PMCID:: PMC3589879

Abstract Article PDF–536K

Select item 335961216.

Notch1 Is Regulated by Chorionic Gonadotropin and Progesterone in Endometrial Stromal Cells and Modulates Decidualization in Primates

Yalda Afshar, Lucio Miele, Asgerally T. Fazleabas

Endocrinology. 2012 Jun; 153(6): 2884–2896. Published online 2012 Apr 24. doi: 10.1210/en.2011-2122

PMCID:: PMC3359612

Abstract Article

Select item 296305817.

Complex Expression Pattern of Wnt Ligands and Frizzled Receptors in Human Placenta and its Trophoblast Subtypes

S. Sonderegger, H. Husslein, C. Leisser, M. Knöfler

Placenta. Author manuscript; available in PMC 2010 Oct 25.

Published in final edited form as: Placenta. 2007 Apr; 28(Suppl A): S97–102. Published online 2007 Jan 2. doi: 10.1016/j.placenta.2006.11.003

PMCID:: PMC2963058

Abstract Article PDF–349K

Select item 290451218.

Wnt/Ca²⁺/NFAT signaling maintains survival of Ph⁺ leukemia cells upon inhibition of Bcr-Abl

Mark A. Gregory, Tzu L. Phang, Paolo Neviani, Francesca Alvarez-Calderon, Christopher A. Eide, Thomas O’Hare, Vadym Zaberezhnyy, Richard T. Williams, Brian J. Druker, Danilo Perrotti, James DeGregori

Cancer Cell. Author manuscript; available in PMC 2011 Jul 13.

Published in final edited form as: Cancer Cell. 2010 Jul 13; 18(1): 74–87. doi: 10.1016/j.ccr.2010.04.025