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Items: 1 to 20 of 33

1.
RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance
Ranganatha R. Somasagara, Sebastian M. Spencer, Kaushlendra Tripathi, David W. Clark, Chinnadurai Mani, Luciana Madeira da Silva, Jennifer Scalici, Hend Kothayer, Andrew D. Westwell, Rodney P. Rocconi, Komaraiah Palle
Oncogene. Author manuscript; available in PMC 2018 Feb 14.
Published in final edited form as: Oncogene. 2017 Nov 30; 36(48): 6680–6690. Published online 2017 Aug 14. doi: 10.1038/onc.2017.279
PMCID:
PMC5709226
AbstractArticlePDF–1.3M
2.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
3.
Pharmacological targeting of RAD6 enzyme-mediated translesion synthesis overcomes resistance to platinum-based drugs
Matthew A. Sanders, Brittany Haynes, Pratima Nangia-Makker, Lisa A. Polin, Malathy P. Shekhar
J Biol Chem. 2017 Jun 23; 292(25): 10347–10363. Published online 2017 May 10. doi: 10.1074/jbc.M117.792192
PMCID:
PMC5481549
AbstractArticlePDF–4.9M
4.
Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage
Hongli An, Lu Yang, Chen Wang, Zhixue Gan, Haihui Gu, Tao Zhang, Xin Huang, Yan Liu, Yufeng Li, Shing-Jyh Chang, Jianghua Lai, Ya-Bin Li, Su Chen, Fang-Lin Sun
Mol Cell Biol. 2017 Mar 15; 37(6): e00419-16. Prepublished online 2016 Dec 28. Published online 2017 Mar 1. doi: 10.1128/MCB.00419-16
PMCID:
PMC5335506
AbstractArticlePDF–4.8M
5.
Role of E2- RING interactions in governing RNF4-mediated substrate ubiquitination
Anthony DiBello, Ajit B. Datta, Xiangbin Zhang, Cynthia Wolberger
J Mol Biol. Author manuscript; available in PMC 2017 Nov 20.
Published in final edited form as: J Mol Biol. 2016 Nov 20; 428(23): 4639–4650. Published online 2016 Sep 24. doi: 10.1016/j.jmb.2016.09.018
PMCID:
PMC5115946
AbstractArticlePDF–1.1M
6.
The human ubiquitin carrier protein E2(Mr = 17,000) is homologous to the yeast DNA repair gene RAD6.
R Schneider, C Eckerskorn, F Lottspeich, M Schweiger
EMBO J. 1990 May; 9(5): 1431–1435. doi: 10.1002/j.1460-2075.1990.tb08259.x
PMCID:
PMC551831
SummaryPage BrowsePDF–930K
7.
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
M H Koken, P Reynolds, I Jaspers-Dekker, L Prakash, S Prakash, D Bootsma, J H Hoeijmakers
Proc Natl Acad Sci U S A. 1991 Oct 15; 88(20): 8865–8869. doi: 10.1073/pnas.88.20.8865
PMCID:
PMC52611
SummaryPage BrowsePDF–1.2M
8.
Alternative Splicing of RAD6B and Not RAD6A Is Selectively Increased in Melanoma: Identification and Functional Characterization
Ambikai Gajan, Carly E. Martin, Seongho Kim, Milap Joshi, Sharon K. Michelhaugh, Ido Sloma, Sandeep Mittal, Steven Firestine, Malathy P. V. Shekhar
Cells. 2019 Nov; 8(11): 1375. Published online 2019 Nov 1. doi: 10.3390/cells8111375
PMCID:
PMC6912459
AbstractArticlePDF–1.9M
9.
A 2x folic acid treatment affects epigenetics and dendritic spine densities in SHSY5Y cells
Rahaf Al Sayed, Whitnei Smith, Nicole Rogers, Nuri Smith, Daniel Clark, Gabriel Castillo, Hunter McLeod, Stewart Glenister, Kimberly R. Shorter
Biochem Biophys Rep. 2019 Dec; 20: 100681. Published online 2019 Aug 17. doi: 10.1016/j.bbrep.2019.100681
PMCID:
PMC6711848
AbstractArticlePDF–1.0M
10.
Global transcriptome profile reveals abundance of DNA damage response and repair genes in individuals from high level natural radiation areas of Kerala coast
Vinay Jain, Birajalaxmi Das
PLoS One. 2017; 12(11): e0187274. Published online 2017 Nov 21. doi: 10.1371/journal.pone.0187274
PMCID:
PMC5697823
AbstractArticlePDF–16M
11.
Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells
Mary F. Lopez, Ping Niu, Lu Wang, Maryann Vogelsang, Meenakshi Gaur, Bryan Krastins, Yueqiang Zhao, Aibek Smagul, Aliya Nussupbekova, Aikan A. Akanov, I. King Jordan, Victoria V. Lunyak
NPJ Aging Mech Dis. 2017; 3: 7. Published online 2017 Apr 20. doi: 10.1038/s41514-017-0006-y
PMCID:
PMC5460214
AbstractArticlePDF–2.9M
12.
Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes
Xinliang Zhao, Xiaoyan Dong, Xiucui Luo, Jing Pan, Weina Ju, Meijiao Zhang, Peirong Wang, Mei Zhong, Yanhong Yu, W. Ted Brown, Nanbert Zhong
Front Pharmacol. 2017; 8: 310. Published online 2017 Jun 2. doi: 10.3389/fphar.2017.00310
PMCID:
PMC5455099
AbstractArticlePDF–1.4M
13.
Proton Beams Inhibit Proliferation of Breast Cancer Cells by Altering DNA Methylation Status
Byungtak Kim, Hansol Bae, Hyunkyung Lee, Seungyeon Lee, Jeong Chan Park, Kye Ryung Kim, Sun Jung Kim
J Cancer. 2016; 7(3): 344–352. Published online 2016 Jan 10. doi: 10.7150/jca.13396
PMCID:
PMC4747889
AbstractArticlePDF–1.0M
14.
A conserved set of maternal genes? Insights from a molluscan transcriptome
M. MAUREEN LIU, JOHN W. DAVEY, DANIEL J. JACKSON, MARK L. BLAXTER, ANGUS DAVISON
Int J Dev Biol. Author manuscript; available in PMC 2015 Oct 6.
Published in final edited form as: Int J Dev Biol. 2014; 58(6-8): 501–511. doi: 10.1387/ijdb.140121ad
PMCID:
PMC4594767
AbstractArticlePDF–1004K
15.
Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin
Brigitte Gerard, Matthew A. Sanders, Daniel W. Visscher, Larry Tait, Malathy P.V. Shekhar
Biochim Biophys Acta. Author manuscript; available in PMC 2014 Feb 6.
Published in final edited form as: Biochim Biophys Acta. 2012 Oct; 1823(10): 1686–1696. Published online 2012 Jun 15. doi: 10.1016/j.bbamcr.2012.05.032
Correction in:
volume 1833 on page 1280
PMCID:
PMC3915360
AbstractArticlePDF–3.5M
16.
Microfluidic affinity and ChIP-seq analyses converge on a conserved FOXP2-binding motif in chimp and human, which enables the detection of evolutionarily novel targets
Christopher S. Nelson, Chris K. Fuller, Polly M. Fordyce, Alexander L. Greninger, Hao Li, Joseph L. DeRisi
Nucleic Acids Res. 2013 Jul; 41(12): 5991–6004. Published online 2013 May 18. doi: 10.1093/nar/gkt259
PMCID:
PMC3695516
AbstractArticlePDF–450K
17.
Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB
Deok-Soo Son, Syder M. Kabir, Yuan-Lin Dong, Eunsook Lee, Samuel E. Adunyah
PLoS One. 2012; 7(12): e51116. Published online 2012 Dec 31. doi: 10.1371/journal.pone.0051116
PMCID:
PMC3534106
AbstractArticlePDF–2.2M
18.
In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data
Qi Liu, Han Zhou, Kui Zhang, Xiaoxiao Shi, Wei Fan, Ruixin Zhu, Philip S. Yu, Zhiwei Cao
PLoS One. 2012; 7(12): e50697. Published online 2012 Dec 21. doi: 10.1371/journal.pone.0050697
PMCID:
PMC3528743
AbstractArticlePDF–1.0M
19.
A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen
Yi Sheng, Jenny H. Hong, Ryan Doherty, Tharan Srikumar, Jonathan Shloush, George V. Avvakumov, John R. Walker, Sheng Xue, Dante Neculai, Janet W. Wan, Sung K. Kim, Cheryl H. Arrowsmith, Brian Raught, Sirano Dhe-Paganon
Mol Cell Proteomics. 2012 Aug; 11(8): 329–341. Published online 2012 Apr 10. doi: 10.1074/mcp.O111.013706
PMCID:
PMC3412965
AbstractArticlePDF–2.4M
20.
Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress
Anne G Lundemo, Caroline HH Pettersen, Kjetil Berge, Rolf K Berge, Svanhild A Schønberg
Lipids Health Dis. 2011; 10: 190. Published online 2011 Oct 25. doi: 10.1186/1476-511X-10-190
PMCID:
PMC3235040
AbstractArticlePDF–1.7M

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