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Items: 15

1.
TRANSCRIPTIONAL ACTIVATION OF RAGD GTPASE CONTROLS mTORC1 AND PROMOTES CANCER GROWTH
Chiara Di Malta, Diletta Siciliano, Alessia Calcagni, Jlenia Monfregola, Simona Punzi, Nunzia Pastore, Andrea N. Eastes, Oliver Davis, Rossella de Cegli, Angela Zampelli, Luca G. Di Giovannantonio, Edoardo Nusco, Nick Platt, Alessandro Guida, Margret Helga Ogmundsdottir, Luisa Lanfrancone, Rushika M. Perera, Roberto Zoncu, Pier Giuseppe Pelicci, Carmine Settembre, Andrea Ballabio.
Science. Author manuscript; available in PMC 2017 Dec 16.
Published in final edited form as: Science. 2017 Jun 16; 356(6343): 1188–1192. doi: 10.1126/science.aag2553
PMCID:
PMC5730647
AbstractArticlePDF–521K
2.
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction
Jong Hyun Kim, Chulho Lee, Minji Lee, Haipeng Wang, Kibum Kim, Seung Joon Park, Ina Yoon, Jayun Jang, Hanchao Zhao, Hoi Kyoung Kim, Nam Hoon Kwon, Seung Jae Jeong, Hee Chan Yoo, Jae Hyun Kim, Jee Sun Yang, Myeong Youl Lee, Chang Woo Lee, Jieun Yun, Soo Jin Oh, Jong Soon Kang, Susan A. Martinis, Kwang Yeon Hwang, Min Guo, Gyoonhee Han, Jung Min Han, Sunghoon Kim
Nat Commun. 2017; 8: 732. Published online 2017 Sep 29. doi: 10.1038/s41467-017-00785-0
PMCID:
PMC5622079
AbstractArticlePDF–2.0M
3.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
4.
SLC38A9 is a component of the lysosomal amino acid-sensing machinery that controls mTORC1
Manuele Rebsamen, Lorena Pochini, Taras Stasyk, Mariana E. G. de Araújo, Michele Galluccio, Richard K. Kandasamy, Berend Snijder, Astrid Fauster, Elena L. Rudashevskaya, Manuela Bruckner, Stefania Scorzoni, Przemyslaw A. Filipek, Kilian V. M. Huber, Johannes Bigenzahn, Leonhard X. Heinz, Claudine Kraft, Keiryn L. Bennett, Cesare Indiveri, Lukas A. Huber, Giulio Superti-Furga
Nature. Author manuscript; available in PMC 2015 Sep 26.
Published in final edited form as: Nature. 2015 Mar 26; 519(7544): 477–481. Published online 2015 Jan 7. doi: 10.1038/nature14107
PMCID:
PMC4376665
AbstractArticlePDF–2.4M
5.
Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
Min Peng, Na Yin, Ming O. Li
Cell. Author manuscript; available in PMC 2015 Sep 25.
Published in final edited form as: Cell. 2014 Sep 25; 159(1): 122–133. doi: 10.1016/j.cell.2014.08.038
PMCID:
PMC4181352
AbstractArticlePDF–2.7M
6.
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
Yasemin Sancak, Liron Bar-Peled, Roberto Zoncu, Andrew L. Markhard, Shigeyuki Nada, David M. Sabatini
Cell. Author manuscript; available in PMC 2011 Jan 21.
Published in final edited form as: Cell. 2010 Apr 16; 141(2): 290–303. Published online 2010 Apr 8. doi: 10.1016/j.cell.2010.02.024
PMCID:
PMC3024592
AbstractArticlePDF–5.5M
7.
Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays
N J W de Wit, J Rijntjes, J H S Diepstra, T H van Kuppevelt, U H Weidle, D J Ruiter, G N P van Muijen
Br J Cancer. 2005 Jun 20; 92(12): 2249–2261. Published online 2005 May 17. doi: 10.1038/sj.bjc.6602612
PMCID:
PMC2361822
AbstractArticlePDF–304K
8.
Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells
Yoshio Sakai, Masao Honda, Shigeyuki Matsui, Osamu Komori, Toshinori Murayama, Tadami Fujiwara, Masaaki Mizuno, Yasuhito Imai, Kenichi Yoshimura, Alessandro Nasti, Takashi Wada, Noriho Iida, Masaaki Kitahara, Rika Horii, Tamai Toshikatsu, Masashi Nishikawa, Hirofumi Okafuji, Eishiro Mizukoshi, Tatsuya Yamashita, Taro Yamashita, Kuniaki Arai, Kazuya Kitamura, Kazunori Kawaguchi, Hajime Takatori, Tetsuro Shimakami, Takeshi Terashima, Tomoyuki Hayashi, Kouki Nio, Shuichi Kaneko, Hokuriku Liver Study Group
Cancer Sci. 2019 Apr; 110(4): 1364–1388. Published online 2019 Mar 27. doi: 10.1111/cas.13971
Correction in:
Cancer Sci. 2019 Nov; 110(11): 3615.
PMCID:
PMC6447845
AbstractArticlePDF–644K
9.
Characterization of human dental pulp cells grown in chemically defined serum-free medium
Sakiko Fujii, Katsumi Fujimoto, Noriko Goto, Yoshimitsu Abiko, Asayo Imaoka, Jinchang Shao, Kazuko Kitayama, Masami Kanawa, Agung Sosiawan, Ketut Suardita, Fusanori Nishimura, Yukio Kato
Biomed Rep. 2018 Apr; 8(4): 350–358. Published online 2018 Feb 16. doi: 10.3892/br.2018.1066
PMCID:
PMC5844140
AbstractArticlePDF–913K
10.
Single-cell transcriptomics of East-Asian pancreatic islets cells
Rajkumar Dorajoo, Yusuf Ali, Vanessa S. Y. Tay, Jonathan Kang, Sudhagar Samydurai, Jianjun Liu, Bernhard O. Boehm
Sci Rep. 2017; 7: 5024. Published online 2017 Jul 10. doi: 10.1038/s41598-017-05266-4
PMCID:
PMC5504042
AbstractArticlePDF–1.7M
11.
Skeletal Muscle Ras-Related GTP Binding B mRNA and Protein Expression Is Increased after Essential Amino Acid Ingestion in Healthy Humans
Matthew B. Carlin, Ruth E. Tanner, Jakob Agergaard, Thunder Jalili, Donald A. McClain, Micah J. Drummond
J Nutr. 2014 Sep; 144(9): 1409–1414. Published online 2014 Jul 23. doi: 10.3945/jn.114.196691
PMCID:
PMC4130827
AbstractArticlePDF–748K
12.
Gene Expression Profile in Human Skeletal Muscle Cells Infected With Human Adenovirus Type 36
Zhong Q. Wang, Yongmei Yu, Xian H. Zhang, Jianhua Qin, Elizabeth Floyd
J Med Virol. Author manuscript; available in PMC 2014 Mar 24.
Published in final edited form as: J Med Virol. 2012 Aug; 84(8): 1254–1266. doi: 10.1002/jmv.23332
PMCID:
PMC3962840
AbstractArticlePDF–2.6M
13.
Stem cell-like ALDHbright cellular states in EGFR-mutant non-small cell lung cancer: A novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin
Bruna Corominas-Faja, Cristina Oliveras-Ferraros, Elisabet Cuyàs, Antonio Segura-Carretero, Jorge Joven, Begoña Martin-Castillo, Enrique Barrajón-Catalán, Vicente Micol, Joaquim Bosch-Barrera, Javier A Menendez
Cell Cycle. 2013 Nov 1; 12(21): 3390–3404. Published online 2013 Sep 17. doi: 10.4161/cc.26417
PMCID:
PMC3895428
AbstractArticlePDF–1.4M
14.
Transcriptomic Analysis of Postmortem Brain identifies Dysregulated Splicing Events in Novel Candidate Genes for Schizophrenia
Ori S. Cohen, Sarah Y. Mccoy, Frank A. Middleton, Sean Bialosuknia, Yanli Zhang-James, Lu Liu, Ming T. Tsuang, Stephen V. Faraone, Stephen J. Glatt
Schizophr Res. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Schizophr Res. 2012 Dec; 142(1-3): 188–199. Published online 2012 Oct 9. doi: 10.1016/j.schres.2012.09.015
PMCID:
PMC3502694
AbstractArticlePDF–678K
15.
Androgen regulation of gene expression in human meibomian gland and conjunctival epithelial cells
Payal Khandelwal, Shaohui Liu, David A. Sullivan
Mol Vis. 2012; 18: 1055–1067. Published online 2012 Apr 27.
PMCID:
PMC3351406
AbstractArticlePDF–1.4M

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