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Select item 67947351.

Uridine diphosphate glucuronosyl transferase 1A (UGT1A1) promoter polymorphism in young patients with sickle cell anaemia: report of the first cohort study from Nigeria

Oladele Simeon Olatunya, Dulcineia Martins Albuquerque, Ganiyu Olusola Akanbi, Olufunso Simisola Aduayi, Adekunle Bamidele Taiwo, Opeyemi Ayodeji Faboya, Tolorunju Segun Kayode, Daniela Pinheiro Leonardo, Adekunle Adekile, Fernando Ferreira Costa

BMC Med Genet. 2019; 20: 160. Published online 2019 Oct 16. doi: 10.1186/s12881-019-0899-3

PMCID:: PMC6794735

Abstract Article PDF–359K

Select item 66993452.

Analysis of the UGT1A1 Genotype in Hyperbilirubinemia Patients: Differences in Allele Frequency and Distribution

Xiao-xiao Mi, Jian Yan, Xiao-jie Ma, Ge-li Zhu, Yi-dan Gao, Wen-jun Yang, Xiao-wen Kong, Gong-ying Chen, Jun-ping Shi, Ling Gong

Biomed Res Int. 2019; 2019: 6272174. Published online 2019 Jul 29. doi: 10.1155/2019/6272174

PMCID:: PMC6699345

Abstract Article PDF–1.2M

Select item 65443003.

Mechanism of the efflux transport of demethoxycurcumin-O-glucuronides in HeLa cells stably transfected with UDP-glucuronosyltransferase 1A1

Beibei Zhang, Jing Yang, Zifei Qin, Shishi Li, Jinjin Xu, Zhihong Yao, Xiaojian Zhang, Frank J. Gonzalez, Xinsheng Yao

PLoS One. 2019; 14(5): e0217695. Published online 2019 May 31. doi: 10.1371/journal.pone.0217695

PMCID:: PMC6544300

Abstract Article PDF–1.9M

Select item 4430744.

Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient.

J K Ritter, M T Yeatman, P Ferreira, I S Owens

J Clin Invest. 1992 Jul; 90(1): 150–155. doi: 10.1172/JCI115829

PMCID:: PMC443074

Summary Page Browse PDF–1.4M

Select item 63105755.

UGT1A1 genotypes and unconjugated hyperbilirubinemia phenotypes in post-neonatal Chinese children: A retrospective analysis and quantitative correlation

Kuerbanjiang Abuduxikuer, Ling-Juan Fang, Li-Ting Li, Jing-Yu Gong, Jian-She Wang

Medicine (Baltimore) 2018 Dec; 97(49): e13576. Published online 2018 Dec 10. doi: 10.1097/MD.0000000000013576

PMCID:: PMC6310575

Abstract Article PDF–650K

Select item 58439976.

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen

Oncol Lett. 2018 Mar; 15(3): 3726–3734. Published online 2018 Jan 16. doi: 10.3892/ol.2018.7808

PMCID:: PMC5843997

Abstract Article PDF–1.5M

Select item 58359107.

Monitoring colorectal cancer following surgery using plasma circulating tumor DNA

Xiao Sun, Tanxiao Huang, Fangsheng Cheng, Kaibing Huang, Ming Liu, Wan He, Mingwei Li, Xiaoni Zhang, Mingyan Xu, Shifu Chen, Ligang Xia

Oncol Lett. 2018 Apr; 15(4): 4365–4375. Published online 2018 Jan 22. doi: 10.3892/ol.2018.7837

PMCID:: PMC5835910

Abstract Article PDF–1.2M

Select item 58280938.

UGT1A1 Genetic Variations and a Haplotype Associated with Neonatal Hyperbilirubinemia in Indonesian Population

Dewi A. Wisnumurti, Yunia Sribudiani, Robert M. Porsch, Ani M. Maskoen, Lola I. Abdulhamied, Sri E. Rahayuningsih, Eni K. Asni, Frank Sleutels, Christel E. M. Kockx, Wilfred F. J. van Ijcken, Abdurachman Sukadi, Tri H. Achmad

Biomed Res Int. 2018; 2018: 9425843. Published online 2018 Jan 23. doi: 10.1155/2018/9425843

PMCID:: PMC5828093

Abstract Article PDF–1.6M

Select item 53580139.

Establishment and Use of New MDCK II Cells Overexpressing Both UGT1A1 and MRP2 to Characterize Flavonoid Metabolism via the Glucuronidation Pathway

Meifang Wang, Guangyi Yang, Yu He, Beibei Xu, Min Zeng, Taijun Yin, Song Gao, Ming Hu

Mol Nutr Food Res. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Mol Nutr Food Res. 2016 Sep; 60(9): 1967–1983. Published online 2016 Jul 6. doi: 10.1002/mnfr.201500321

PMCID:: PMC5358013

Abstract Article PDF–2.9M

Select item 499226110.

2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer

Lora J. Rogers, Alexei G. Basnakian, Mohammed S. Orloff, Baitang Ning, Aiwei Yao-Borengasser, Vinay Raj, Susan Kadlubar

Nutr Metab (Lond) 2016; 13: 54. Published online 2016 Aug 20. doi: 10.1186/s12986-016-0111-0

PMCID:: PMC4992261

Abstract Article PDF–1.4M

Select item 483741511.

Dimerization of human uridine diphosphate glucuronosyltransferase allozymes 1A1 and 1A9 alters their quercetin glucuronidation activities

Yan-Qing Liu, Ling-Min Yuan, Zhang-Zhao Gao, Yong-Sheng Xiao, Hong-Ying Sun, Lu-Shan Yu, Su Zeng

Sci Rep. 2016; 6: 23763. Published online 2016 Mar 30. doi: 10.1038/srep23763

PMCID:: PMC4837415

Abstract Article PDF–1.4M

Select item 482171812.

Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor

Lina Ren, John D. Thompson, Michael Cheung, Katherine Ngo, Sarah Sung, Scott Leong, William K. Chan

Biochem Pharmacol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Biochem Pharmacol. 2016 May 1; 107: 91–100. Published online 2016 Mar 9. doi: 10.1016/j.bcp.2016.03.004

PMCID:: PMC4821718

Abstract Article PDF–3.9M

Select item 474454613.

Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP

Shufan Ge, Taijun Yin, Beibei Xu, Song Gao, Ming Hu

Pharm Res. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Pharm Res. 2016 Mar; 33(3): 590–602. Published online 2015 Oct 26. doi: 10.1007/s11095-015-1812-1

PMCID:: PMC4744546

Abstract Article PDF–1.2M

Select item 448097314.

Identification of a Novel p.Q1772X ANK1 Mutation in a Korean Family with Hereditary Spherocytosis

Joo Hyung Han, Seung Kim, Hoon Jang, So Won Kim, Min Goo Lee, Hong Koh, Ji Hyun Lee

PLoS One. 2015; 10(6): e0131251. Published online 2015 Jun 24. doi: 10.1371/journal.pone.0131251

PMCID:: PMC4480973

Abstract Article PDF–720K

Select item 447499615.

Establishment of a stable aryl hydrocarbon receptor-responsive HepG2 cell line

Hideo Satsu, Kazutaka Yoshida, Ayano Mikubo, Haru Ogiwara, Takahiro Inakuma, Makoto Shimizu

Cytotechnology. 2015 Aug; 67(4): 621–632. Published online 2014 Mar 26. doi: 10.1007/s10616-014-9711-6

PMCID:: PMC4474996

Abstract Article PDF–728K

Select item 413805316.

The sonic hedgehog factor Gli1 imparts drug resistance through inducible glucuronidation

Hiba Ahmad Zahreddine, Biljana Culjkovic-Kraljacic, Sarit Assouline, Patrick Gendron, Andrea A. Romeo, Stephen J. Morris, Gregory Cormack, James B. Jaquith, Leandro Cerchietti, Eftihia Cocolakis, Abdellatif Amri, Julie Bergeron, Brian Leber, Michael W. Becker, Shanshan Pei, Craig T. Jordan, Wilson H. Miller, Jr, Katherine L.B. Borden

Nature. Author manuscript; available in PMC 2015 Jan 3.

Published in final edited form as: Nature. 2014 Jul 3; 511(7507): 90–93. Published online 2014 May 28. doi: 10.1038/nature13283

PMCID:: PMC4138053

Article PDF–2.8M

Select item 404458317.

Genetic variation in the 3′-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance

Marelize Swart, Collet Dandara

Front Genet. 2014; 5: 167. Published online 2014 Jun 4. doi: 10.3389/fgene.2014.00167

PMCID:: PMC4044583

Abstract Article PDF–461K

Select item 346571618.

Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated Phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates

Constance Lay-Lay Saw, Melvilí Cintron, Tien-Yuan Wu, Yue Guo, Ying Huang, Woo-Sik Jeong, Ah-Ng Tony Kong

Biopharm Drug Dispos. Author manuscript; available in PMC 2012 Oct 7.

Published in final edited form as: Biopharm Drug Dispos. 2011 Jul; 32(5): 289–300. Published online 2011 Jun 8. doi: 10.1002/bdd.759

PMCID:: PMC3465716

Abstract Article PDF–1001K

Select item 343860019.

XIAONAN KANG, NIAN WANG, CHEN PEI, LU SUN, RUIXIA SUN, JIE CHEN, YINKUN LIU

Exp Ther Med. 2012 Mar; 3(3): 415–422. Published online 2011 Dec 23. doi: 10.3892/etm.2011.430

PMCID:: PMC3438600

Abstract Article PDF–785K

Select item 323186620.

Biomarkers for Drug-Induced Renal Damage and Nephrotoxicity—An Overview for Applied Toxicology

Tobias Christian Fuchs, Philip Hewitt

AAPS J. 2011 Dec; 13(4): 615–631. Published online 2011 Oct 4. doi: 10.1208/s12248-011-9301-x

PMCID:: PMC3231866

Abstract Article PDF–382K

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PMC Links for Nucleotide (Select 1732746141) (26)
PMC
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_24_length_4833_c...
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_24_length_4833_cov_37.741234, whole genome shotgun sequence
gi|1473550711|ref|NZ_MJBJ02000024.1 |WGS:NZ_MJBJ02|NODE_24_length_4833_cov_37.741234

Nucleotide
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_32_length_1412_c...
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_32_length_1412_cov_171.793602, whole genome shotgun sequence
gi|1473550719|ref|NZ_MJBJ02000032.1 |WGS:NZ_MJBJ02|NODE_32_length_1412_cov_171.793602

Nucleotide
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_28_length_2599_c...
Macrococcoides caseolyticum subsp. hominis strain CCM 7927 NODE_28_length_2599_cov_27.946400, whole genome shotgun sequence
gi|1473550715|ref|NZ_MJBJ02000028.1 |WGS:NZ_MJBJ02|NODE_28_length_2599_cov_27.946400

Nucleotide
PREDICTED: Homo sapiens misato mitochondrial distribution and morphology regulat...
PREDICTED: Homo sapiens misato mitochondrial distribution and morphology regulator 1 (MSTO1), transcript variant X14, mRNA
gi|2462510772|ref|XM_054337369.1|

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