PMC Links for Nucleotide (Select 1732746237) - PMC

Ingrid M. Ariës, Kimberly Bodaar, Salmaan A. Karim, Triona Ni Chonghaile, Laura Hinze, Melissa A. Burns, Maren Pfirrmann, James Degar, Jack T. Landrigan, Sebastian Balbach, Sofie Peirs, Björn Menten, Randi Isenhart, Kristen E. Stevenson, Donna S. Neuberg, Meenakshi Devidas, Mignon L. Loh, Stephen P. Hunger, David T. Teachey, Karen R. Rabin, Stuart S. Winter, Kimberly P. Dunsmore, Brent L. Wood, Lewis B. Silverman, Stephen E. Sallan, Pieter Van Vlierberghe, Stuart H. Orkin, Birgit Knoechel, Anthony G. Letai, Alejandro Gutierrez

J Exp Med. 2018 Dec 3; 215(12): 3094–3114. doi: 10.1084/jem.20180570

PMCID:: PMC6279404

Abstract Article PDF–3.0M

Select item 61947545.

Effects of Enhancer of Zeste Homolog 2 (EZH2) Expression on Brain Glioma Cell Proliferation and Tumorigenesis

Tianci Cheng, Yinghui Xu

Med Sci Monit. 2018; 24: 7249–7255. Published online 2018 Oct 11. doi: 10.12659/MSM.909814

PMCID:: PMC6194754

Abstract Article PDF–747K

Select item 61288656.

Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

Yusuke Shiozawa, Luca Malcovati, Anna Gallì, Aiko Sato-Otsubo, Keisuke Kataoka, Yusuke Sato, Yosaku Watatani, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Masashi Sanada, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Eva Hellström-Lindberg, Satoru Miyano, Seishi Ogawa, Mario Cazzola

Nat Commun. 2018; 9: 3649. Published online 2018 Sep 7. doi: 10.1038/s41467-018-06063-x

PMCID:: PMC6128865

Abstract Article PDF–3.1M

Select item 60587977.

Down syndrome-like acute megakaryoblastic leukemia in a patient with Cornelia de Lange syndrome

Yoann Vial, Julie Lachenaud, Alain Verloes, Marianne Besnard, Odile Fenneteau, Elodie Lainey, Alice Marceau-Renaut, Claude Preudhomme, André Baruchel, Hélène Cavé, Séverine Drunat

Haematologica. 2018 Jun; 103(6): e274–e276. doi: 10.3324/haematol.2017.178590

PMCID:: PMC6058797

Article PDF–382K

Select item 59197138.

Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation

Guiju Tang, Jianfeng Guo, Yapei Zhu, Zaiju Huang, Ting Liu, Jing Cai, Lili Yu, Zehua Wang

Int J Oncol. 2018 Jun; 52(6): 1899–1911. Published online 2018 Mar 29. doi: 10.3892/ijo.2018.4343

PMCID:: PMC5919713

Abstract Article PDF–2.0M

Select item 57789229.

Inhibition of enhancer of zeste homolog 2 increases the expression of p16 and suppresses the proliferation and migration of ovarian carcinoma cells in vitro and in vivo

Fangfang Lu, Hong Xu, Qi Wang, Meiyi Li, Jiahua Meng, Yan Kuang

Oncol Lett. 2018 Mar; 15(3): 3233–3239. Published online 2017 Dec 28. doi: 10.3892/ol.2017.7712

PMCID:: PMC5778922

Abstract Article PDF–1.1M

Select item 570718510.

Detection of Mutations in Myeloid Malignancies through Paired-Sample Analysis of Microdroplet-PCR Deep Sequencing Data

Donavan T. Cheng, Janice Cheng, Talia N. Mitchell, Aijazuddin Syed, Ahmet Zehir, Nana Yaa T. Mensah, Alifya Oultache, Khedoudja Nafa, Ross L. Levine, Maria E. Arcila, Michael F. Berger, Cyrus V. Hedvat

J Mol Diagn. 2014 Sep; 16(5): 504–518. doi: 10.1016/j.jmoldx.2014.05.006

PMCID:: PMC5707185

Abstract Article PDF–1.3M

Select item 566567711.

Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate

Mariaelena Pistoni, Nicky Helsen, Jolien Vanhove, Ruben Boon, Zhuofei Xu, Laura Ordovas, Catherine M. Verfaillie

PLoS One. 2017; 12(11): e0186884. Published online 2017 Nov 1. doi: 10.1371/journal.pone.0186884

PMCID:: PMC5665677

Abstract Article PDF–2.0M

Select item 562027712.

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells

Evelina Miele, Sergio Valente, Vincenzo Alfano, Marianna Silvano, Paolo Mellini, Diana Borovika, Biagina Marrocco, Agnese Po, Zein Mersini Besharat, Giuseppina Catanzaro, Giuseppe Battaglia, Luana Abballe, Clemens Zwergel, Giulia Stazi, Ciro Milite, Sabrina Castellano, Marco Tafani, Peteris Trapencieris, Antonello Mai, Elisabetta Ferretti

Oncotarget. 2017 Sep 15; 8(40): 68557–68570. Published online 2017 Aug 2. doi: 10.18632/oncotarget.19782

PMCID:: PMC5620277

Abstract Article PDF–2.9M

Select item 554707613.

MUC1-C activates EZH2 expression and function in human cancer cells

Hasan Rajabi, Masayuki Hiraki, Ashujit Tagde, Maroof Alam, Audrey Bouillez, Camilla L. Christensen, Mehmet Samur, Kwok-Kin Wong, Donald Kufe

Sci Rep. 2017; 7: 7481. Published online 2017 Aug 7. doi: 10.1038/s41598-017-07850-0

PMCID:: PMC5547076

Abstract Article PDF–2.9M

Select item 542035514.

Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability

Katrina Tatton-Brown, Chey Loveday, Shawn Yost, Matthew Clarke, Emma Ramsay, Anna Zachariou, Anna Elliott, Harriet Wylie, Anna Ardissone, Olaf Rittinger, Fiona Stewart, I. Karen Temple, Trevor Cole, Childhood Overgrowth Collaboration, Shazia Mahamdallie, Sheila Seal, Elise Ruark, Nazneen Rahman

Am J Hum Genet. 2017 May 4; 100(5): 725–736. Published online 2017 May 4. doi: 10.1016/j.ajhg.2017.03.010

PMCID:: PMC5420355

Abstract Article PDF–740K

Select item 538668715.

Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity

Krystal D. Nolan, Jasmine Kaur, Jennifer S. Isaacs

Oncotarget. 2017 Mar 21; 8(12): 19323–19341. Published online 2016 Dec 27. doi: 10.18632/oncotarget.14252

PMCID:: PMC5386687

Abstract Article PDF–5.6M

Select item 509697416.

Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2

Huafeng Xie, Cong Peng, Jialiang Huang, Bin E. Li, Woojin Kim, Elenoe C. Smith, Yuko Fujiwara, Jun Qi, Giulia Cheloni, Partha P. Das, Minh Nguyen, Shaoguang Li, James E. Bradner, Stuart H. Orkin

Cancer Discov. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Cancer Discov. 2016 Nov; 6(11): 1237–1247. Published online 2016 Sep 14. doi: 10.1158/2159-8290.CD-15-1439

PMCID:: PMC5096974

Abstract Article PDF–2.0M

Select item 509497417.

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia

Nikos Papakonstantinou, Stavroula Ntoufa, Elisavet Chartomatsidou, Konstantia Kotta, Andreas Agathangelidis, Lefki Giassafaki, Tzeni Karamanli, Panagiota Bele, Theodoros Moysiadis, Panagiotis Baliakas, Lesley Ann Sutton, Niki Stavroyianni, Achilles Anagnostopoulos, Antonios M. Makris, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos

Oncotarget. 2016 Jun 14; 7(24): 35946–35959. Published online 2016 May 14. doi: 10.18632/oncotarget.9371