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Select item 414181.

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.

S Xu, D Robbins, J Frost, A Dang, C Lange-Carter, M H Cobb

Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15): 6808–6812. doi: 10.1073/pnas.92.15.6808

PMCID:: PMC41418

Summary Page Browse PDF–1.3M

Select item 70012062.

Congenital cystic adenomatoid malformations of the lung: an epithelial transcriptomic approach

Guillaume Lezmi, Shamila Vibhushan, Claudia Bevilaqua, Nicolas Crapart, Nicolas Cagnard, Naziha Khen-Dunlop, Christine Boyle-Freyssaut, Alice Hadchouel, Christophe Delacourt

Respir Res. 2020; 21: 43. Published online 2020 Feb 4. doi: 10.1186/s12931-020-1306-5

PMCID:: PMC7001206

Abstract Article PDF–1.9M

Select item 66143603.

Contribution of New Adenomatous Polyposis Predisposition Genes in an Unexplained Attenuated Spanish Cohort by Multigene Panel Testing

Víctor Lorca, Daniel Rueda, Lorena Martín-Morales, María Jesús Fernández-Aceñero, Judith Grolleman, Carmen Poves, Patricia Llovet, Sandra Tapial, Vanesa García-Barberán, Julián Sanz, Pedro Pérez-Segura, Richarda M. de Voer, Eduardo Díaz-Rubio, Miguel de la Hoya, Trinidad Caldés, Pilar Garre

Sci Rep. 2019; 9: 9814. Published online 2019 Jul 8. doi: 10.1038/s41598-019-46403-5

PMCID:: PMC6614360

Abstract Article PDF–1.3M

Select item 59952364.

Concomitant driver mutations in advanced EGFR-mutated non-small-cell lung cancer and their impact on erlotinib treatment

Jan Nyrop Jakobsen, Eric Santoni-Rugiu, Morten Grauslund, Linea Melchior, Jens Benn Sørensen

Oncotarget. 2018 May 25; 9(40): 26195–26208. Published online 2018 May 25. doi: 10.18632/oncotarget.25490

PMCID:: PMC5995236

Abstract Article PDF–2.0M

Select item 58439975.

Sequencing of circulating tumor DNA for dynamic monitoring of gene mutations in advanced non-small cell lung cancer

Ruilian Xu, Guolin Zhong, Tanxiao Huang, Wan He, Cheng Kong, Xiaoni Zhang, Ying Wang, Ming Liu, Mingyan Xu, Shifu Chen

Oncol Lett. 2018 Mar; 15(3): 3726–3734. Published online 2018 Jan 16. doi: 10.3892/ol.2018.7808

PMCID:: PMC5843997

Abstract Article PDF–1.5M

Select item 57886496.

Gene master regulators of papillary and anaplastic thyroid cancers

Dumitru A. Iacobas, Neha Y. Tuli, Sanda Iacobas, John K. Rasamny, Augustine Moscatello, Jan Geliebter, Raj K. Tiwari

Oncotarget. 2018 Jan 5; 9(2): 2410–2424. Published online 2017 Dec 19. doi: 10.18632/oncotarget.23417

PMCID:: PMC5788649

Abstract Article PDF–7.4M

Select item 57835887.

Tumor molecular profiling of NSCLC patients using next generation sequencing

Nikolaos Tsoulos, Eirini Papadopoulou, Vasiliki Metaxa-Mariatou, Georgios Tsaousis, Chrisoula Efstathiadou, Georgia Tounta, Aikaterini Scapeti, Eugenia Bourkoula, Pavlos Zarogoulidis, George Pentheroudakis, Stylianos Kakolyris, Ioannis Boukovinas, Pavlos Papakotoulas, Elias Athanasiadis, Theofanis Floros, Anna Koumarianou, Vasileios Barbounis, Anca Dinischiotu, George Nasioulas

Oncol Rep. 2017 Dec; 38(6): 3419–3429. Published online 2017 Oct 23. doi: 10.3892/or.2017.6051

PMCID:: PMC5783588

Abstract Article PDF–869K

Select item 54481028.

The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

A. Jane Bardwell, Leonila Lagunes, Ronak Zebarjedi, Lee Bardwell

J Biol Chem. 2017 May 26; 292(21): 8750–8761. Published online 2017 Apr 10. doi: 10.1074/jbc.M116.767087

PMCID:: PMC5448102

Abstract Article PDF–2.8M

Select item 54231909.

KLK6‐regulated miRNA networks activate oncogenic pathways in breast cancer subtypes

Konstantinos G. Sidiropoulos, Qiang Ding, Georgios Pampalakis, Nicole M.A. White, Peter Boulos, Georgia Sotiropoulou, George M. Yousef

Mol Oncol. 2016 Aug; 10(7): 993–1007. Published online 2016 Apr 8. doi: 10.1016/j.molonc.2016.03.008

PMCID:: PMC5423190

Abstract Article PDF–4.1M

Select item 538979310.

Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device

Jun-Hee Yoon, Thomas W. Kim, Pedro Mendez, David M. Jablons, Il-Jin Kim

PLoS One. 2017; 12(4): e0174696. Published online 2017 Apr 12. doi: 10.1371/journal.pone.0174696

PMCID:: PMC5389793

Abstract Article PDF–2.2M

Select item 533908311.

Somatic MAP2K1 Mutations Are Associated with Extracranial Arteriovenous Malformation

Javier A. Couto, August Y. Huang, Dennis J. Konczyk, Jeremy A. Goss, Steven J. Fishman, John B. Mulliken, Matthew L. Warman, Arin K. Greene

Am J Hum Genet. 2017 Mar 2; 100(3): 546–554. Published online 2017 Feb 9. doi: 10.1016/j.ajhg.2017.01.018

PMCID:: PMC5339083

Abstract Article PDF–1.3M

Select item 529771512.

Somatic Genetic Variation in Solid Pseudopapillary Tumor of the Pancreas by Whole Exome Sequencing

Meng Guo, Guopei Luo, Kaizhou Jin, Jiang Long, He Cheng, Yu Lu, Zhengshi Wang, Chao Yang, Jin Xu, Quanxing Ni, Xianjun Yu, Chen Liu

Int J Mol Sci. 2017 Jan; 18(1): 81. Published online 2017 Jan 3. doi: 10.3390/ijms18010081

PMCID:: PMC5297715

Abstract Article PDF–1.0M

Select item 521524113.

IL-15 enhances the antitumor effect of human antigen-specific CD8⁺ T cells by cellular senescence delay

Jinsheng Weng, Kelsey E. Moriarty, Flavio Egidio Baio, Fuliang Chu, Sung-Doo Kim, Jin He, Zuliang Jie, Xiaoping Xie, Wencai Ma, Jianfei Qian, Liang Zhang, Jing Yang, Qing Yi, Sattva S. Neelapu, Larry W. Kwak

Oncoimmunology. 2016; 5(12): e1237327. Published online 2016 Oct 7. doi: 10.1080/2162402X.2016.1237327

PMCID:: PMC5215241

Abstract Article PDF–1.1M

Select item 509500214.

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

Sun Min Lim, Hye Ryun Kim, Eun Kyung Cho, Young Joo Min, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Byoung Chul Cho, Ji-Hyun Lee, Hye Cheol Jeong, Eun Kyung Kim, Joo-Hang Kim

Oncotarget. 2016 Jun 14; 7(24): 36311–36320. Published online 2016 Apr 21. doi: 10.18632/oncotarget.8904

PMCID:: PMC5095002

Abstract Article PDF–2.7M

Select item 498500715.

Acquisition of Portal Venous Circulating Tumor Cells From Patients With Pancreaticobiliary Cancers by Endoscopic Ultrasound

Daniel V. T. Catenacci, Christopher G. Chapman, Peng Xu, Ann Koons, Vani J. Konda, Uzma D. Siddiqui, Irving Waxman

Gastroenterology. Author manuscript; available in PMC 2016 Aug 15.

Published in final edited form as: Gastroenterology. 2015 Dec; 149(7): 1794–1803.e4. Published online 2015 Sep 2. doi: 10.1053/j.gastro.2015.08.050

PMCID:: PMC4985007

Abstract Article PDF–1.5M

Select item 494449916.

Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways

Mohammadreza Zamanian, Lama Abdel Qader Hamadneh, Abhi Veerakumarasivam, Sabariah Abdul Rahman, Shamarina Shohaimi, Rozita Rosli

Cancer Cell Int. 2016; 16: 56. Published online 2016 Jul 13. doi: 10.1186/s12935-016-0329-y

PMCID:: PMC4944499

Abstract Article PDF–1.9M

Select item 460701317.

Mutation in NRAS in familial Noonan syndrome – case report and review of the literature

Sara Ekvall, Maria Wilbe, Jovanna Dahlgren, Eric Legius, Arie van Haeringen, Otto Westphal, Göran Annerén, Marie-Louise Bondeson

BMC Med Genet. 2015; 16: 95. Published online 2015 Oct 14. doi: 10.1186/s12881-015-0239-1

PMCID:: PMC4607013

Abstract Article PDF–1018K

Select item 459476718.

A conserved set of maternal genes? Insights from a molluscan transcriptome

M. MAUREEN LIU, JOHN W. DAVEY, DANIEL J. JACKSON, MARK L. BLAXTER, ANGUS DAVISON

Int J Dev Biol. Author manuscript; available in PMC 2015 Oct 6.

Published in final edited form as: Int J Dev Biol. 2014; 58(6-8): 501–511. doi: 10.1387/ijdb.140121ad

PMCID:: PMC4594767

Abstract Article PDF–1004K

Select item 456913719.

Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers

Nicky D’Haene, Marie Le Mercier, Nancy De Nève, Oriane Blanchard, Mélanie Delaunoy, Hakim El Housni, Barbara Dessars, Pierre Heimann, Myriam Remmelink, Pieter Demetter, Sabine Tejpar, Isabelle Salmon

PLoS One. 2015; 10(9): e0138245. Published online 2015 Sep 14. doi: 10.1371/journal.pone.0138245