PMC Links for OMIM (Select 179050) - PMC

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Items: 10

Select item 63180021.

Metabolic reprogramming by the S-nitroso-CoA Reductase system protects from kidney injury

Hua-Lin Zhou, Rongli Zhang, Puneet Anand, Colin T. Stomberski, Zhaoxia Qian, Alfred Hausladen, Liwen Wang, Eugene P. Rhee, Samir M. Parikh, S. Ananth Karumanchi, Jonathan S. Stamler

Nature. Author manuscript; available in PMC 2019 May 28.

Published in final edited form as: Nature. 2019 Jan; 565(7737): 96–100. Published online 2018 Nov 28. doi: 10.1038/s41586-018-0749-z

PMCID:: PMC6318002

Abstract Article PDF–2.9M

Select item 43494522.

Isoform Switch of Pyruvate Kinase M1 Indeed Occurs but Not to Pyruvate Kinase M2 in Human Tumorigenesis

Cheng Zhan, Li Yan, Lin Wang, Jun Ma, Wei Jiang, Yongxing Zhang, Yu Shi, Qun Wang

PLoS One. 2015; 10(3): e0118663. Published online 2015 Mar 4. doi: 10.1371/journal.pone.0118663

PMCID:: PMC4349452

Abstract Article PDF–757K

Select item 38947253.

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Barbara Chaneton, Petra Hillmann, Liang Zheng, Agnès C.L. Martin, Oliver D.K. Maddocks, Achuthanunni Chokkathukalam, Joseph E Coyle, Andris Jankevics, Finn P. Holding, Karen H. Vousden, Christian Frezza, Marc O’Reilly, Eyal Gottlieb

Nature. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Nature. 2012 Nov 15; 491(7424): 458–462. Published online 2012 Oct 14. doi: 10.1038/nature11540

Correction in:: volume 496 on page 386

PMCID:: PMC3894725

Abstract Article PDF–2.2M

Select item 35271234.

SAICAR Stimulates Pyruvate Kinase Isoform M2 and Promotes Cancer Cell Survival in Glucose -Limited Conditions

Kirstie E. Keller, Irene S. Tan, Young-Sam Lee

Science. Author manuscript; available in PMC 2013 May 23.

Published in final edited form as: Science. 2012 Nov 23; 338(6110): 1069–1072. Published online 2012 Oct 18. doi: 10.1126/science.1224409

PMCID:: PMC3527123

Abstract Article PDF–1.0M

Select item 34715355.

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

Dimitrios Anastasiou, George Poulogiannis, John M. Asara, Matthew B. Boxer, Jian-kang Jiang, Min Shen, Gary Bellinger, Atsuo T. Sasaki, Jason W. Locasale, Douglas S. Auld, Craig J. Thomas, Matthew G. Vander Heiden, Lewis C. Cantley

Science. Author manuscript; available in PMC 2012 Oct 15.

Published in final edited form as: Science. 2011 Dec 2; 334(6060): 1278–1283. Published online 2011 Nov 3. doi: 10.1126/science.1211485

PMCID:: PMC3471535

Abstract Article PDF–1.2M

Select item 32481876.

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

Katharina Bluemlein, Nana-Maria Grüning, René G. Feichtinger, Hans Lehrach, Barbara Kofler, Markus Ralser

Oncotarget. 2011 May; 2(5): 393–400. Published online 2011 May 22. doi: 10.18632/oncotarget.278

PMCID:: PMC3248187

Abstract Article PDF–2.1M

Select item 32357057.

Nuclear PKM2 regulates ß-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji, Yanhua Zheng, Ji Liang, Wenhua Huang, Xiang Gao, Kenneth Aldape, Zhimin Lu

Nature. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Nature. 2011 Dec 1; 480(7375): 118–122. doi: 10.1038/nature10598

PMCID:: PMC3235705

Abstract Article PDF–1.6M

Select item 31305648.

Pyruvate Kinase M2 is a PHD3-stimulated Coactivator for Hypoxia-Inducible Factor 1

Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O’Meally, Robert N. Cole, Akhilesh Pandey, Gregg L. Semenza

Cell. Author manuscript; available in PMC 2012 May 27.

Published in final edited form as: Cell. 2011 May 27; 145(5): 732–744. doi: 10.1016/j.cell.2011.03.054

PMCID:: PMC3130564

Abstract Article PDF–3.7M

Select item 30301219.

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

Matthew G. Vander Heiden, Jason W. Locasale, Kenneth D. Swanson, Hadar Sharfi, Greg J. Heffron, Daniel Amador-Noguez, Heather R. Christofk, Gerhard Wagner, Joshua D. Rabinowitz, John M. Asara, Lewis C. Cantley

Science. Author manuscript; available in PMC 2011 Sep 17.

Published in final edited form as: Science. 2010 Sep 17; 329(5998): 1492–1499. doi: 10.1126/science.1188015