PMC Links for OMIM (Select 602170) - PMC

Select item 67367351.

A novel truncating mutation in MYD88 in a patient with BCG adenitis, neutropenia and delayed umbilical cord separation

Craig D. Platt, Fatima Zaman, Jacqueline G. Wallace, Michael Seleman, Janet Chou, Nashat Al Sukaiti, Raif S. Geha

Clin Immunol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Clin Immunol. 2019 Oct; 207: 40–42. Published online 2019 Jul 10. doi: 10.1016/j.clim.2019.07.004

PMCID:: PMC6736735

Abstract Article PDF–583K

Select item 62018422.

A Multiprotein Supercomplex Controlling Oncogenic Signaling in Lymphoma

James D. Phelan, Ryan M. Young, Daniel E. Webster, Sandrine Roulland, George W. Wright, Monica Kasbekar, Arthur L. Shaffer, III, Michele Ceribelli, James Q. Wang, Roland Schmitz, Masao Nakagawa, Emmanuel Bachy, Da Wei Huang, Yanlong Ji, Lu Chen, Yandan Yang, Hong Zhao, Xin Yu, Weihong Xu, Maryknoll M. Palisoc, Racquel R. Valadez, Theresa Davies-Hill, Wyndham H. Wilson, Wing C. Chan, Elaine S. Jaffe, Randy D. Gascoyne, Elias Campo, Andreas Rosenwald, German Ott, Jan Delabie, Lisa M. Rimsza, Fausto J. Rodriguez, Fayez Estephan, Matthias Holdhoff, Michael J. Kruhlak, Stephen M. Hewitt, Craig J. Thomas, Stefania Pittaluga, Thomas Oellerich, Louis M. Staudt

Nature. Author manuscript; available in PMC 2018 Dec 20.

Published in final edited form as: Nature. 2018 Aug; 560(7718): 387–391. Published online 2018 Jun 20. doi: 10.1038/s41586-018-0290-0

PMCID:: PMC6201842

Abstract Article PDF–2.4M

Select item 50245683.

Oncogenically active MYD88 mutations in human lymphoma

Vu N. Ngo, Ryan M. Young, Roland Schmitz, Sameer Jhavar, Wenming Xiao, Kian-Huat Lim, Holger Kohlhammer, Weihong Xu, Yandan Yang, Hong Zhao, Arthur L. Shaffer, Paul Romesser, George Wright, John Powell, Andreas Rosenwald, Hans Konrad Muller-Hermelink, German Ott, Randy D. Gascoyne, Joseph M. Connors, Lisa M. Rimsza, Elias Campo, Elaine S. Jaffe, Jan Delabie, Erlend B. Smeland, Richard I. Fisher, Rita M. Braziel, Raymond R. Tubbs, J. R. Cook, Denny D. Weisenburger, Wing C. Chan, Louis M. Staudt

Nature. Author manuscript; available in PMC 2016 Sep 15.

Published in final edited form as: Nature. 2011 Feb 3; 470(7332): 115–119. Published online 2010 Dec 22. doi: 10.1038/nature09671

PMCID:: PMC5024568

Abstract Article PDF–1.9M

Select item 47126314.

Neutrophil ageing is regulated by the microbiome

Dachuan Zhang, Grace Chen, Deepa Manwani, Arthur Mortha, Chunliang Xu, Jeremiah J. Faith, Robert D. Burk, Yuya Kunisaki, Jung-Eun Jang, Christoph Scheiermann, Miriam Merad, Paul S. Frenette

Nature. Author manuscript; available in PMC 2016 Mar 24.

Published in final edited form as: Nature. 2015 Sep 24; 525(7570): 528–532. Published online 2015 Sep 16. doi: 10.1038/nature15367

PMCID:: PMC4712631

Abstract Article PDF–4.2M

Select item 35218475.

Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability

Weiquan Zhu, Nyall R. London, Christopher C. Gibson, Chadwick T. Davis, Zongzhong Tong, Lise K. Sorensen, Dallas S. Shi, Jinping Guo, Matthew C. P. Smith, Allie H. Grossmann, Kirk R. Thomas, Dean Y. Li

Nature. Author manuscript; available in PMC 2013 Jun 13.

Published in final edited form as: Nature. 2012 Dec 13; 492(7428): 252–255. Published online 2012 Nov 11. doi: 10.1038/nature11603

PMCID:: PMC3521847

Abstract Article PDF–1.5M

Select item 33515826.

DICER1 loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

Valeria Tarallo, Yoshio Hirano, Bradley D. Gelfand, Sami Dridi, Nagaraj Kerur, Younghee Kim, Won Gil Cho, Hiroki Kaneko, Benjamin J. Fowler, Sasha Bogdanovich, Romulo J.C. Albuquerque, William W. Hauswirth, Vince A. Chiodo, Jennifer F. Kugel, James A. Goodrich, Steven L. Ponicsan, Gautam Chaudhuri, Michael P. Murphy, Joshua L. Dunaief, Balamurali K. Ambati, Yuichiro Ogura, Jae Wook Yoo, Dong-ki Lee, Patrick Provost, David R. Hinton, Gabriel Núñez, Judit Z. Baffi, Mark E. Kleinman, Jayakrishna Ambati

Cell. Author manuscript; available in PMC 2013 May 11.

Published in final edited form as: Cell. 2012 May 11; 149(4): 847–859. Published online 2012 Apr 26. doi: 10.1016/j.cell.2012.03.036

PMCID:: PMC3351582

Abstract Article PDF–6.3M

Select item 31038887.

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

Capucine Picard, Horst von Bernuth, Pegah Ghandil, Maya Chrabieh, Ofer Levy, Peter D. Arkwright, Douglas McDonald, Raif S. Geha, Hidetoshi Takada, Jens C. Krause, C. Buddy Creech, Cheng-Lung Ku, Stephan Ehl, Ĺaszĺo Maŕodi, Saleh Al-Muhsen, Sami Al-Hajjar, Abdulaziz Al-Ghonaium, Noorbibi K. Day-Good, Steven M. Holland, John Gallin, Helen Chapel, David P. Speert, Carlos Rodriguez-Gallego, Elena Colino, Ben-Zion Garty, Chaim Roifman, Toshiro Hara, Hideto Yoshikawa, Shigeaki Nonoyama, Joseph Domachowske, Andrew C. Issekutz, Mimi Tang, Joanne Smart, Simona Eva Zitnik, Cyrille Hoarau, Dinakantha Kumararatne, Adrian Thrasher, E. Graham Davies, Claire Bethune, Nicolas Sirvent, Dominique de Ricaud, Yildiz Camcioglu,

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ulia Vasconcelos, Margarida Guedes, Artur Bonito Vitor, Carlos Rodrigo, Francisco AlmaŸan, Maria Ḿendez, Juan Ignacio Aŕostegui, Laia Alsina, Claudia Fortuny, Janine Reichenbach, James W Verbsky, Xavier Bossuyt, Rainer Doffinger, Laurent Abel, Anne Puel, Jean-Laurent Casanova

Medicine (Baltimore) Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Medicine (Baltimore). 2010 Nov; 89(6): 403–425. doi: 10.1097/MD.0b013e3181fd8ec3

PMCID:: PMC3103888

Abstract Article PDF–1.8M

Select item 28886938.

Helical assembly in the MyD88:IRAK4:IRAK2 complex in TLR/IL-1R signaling

Su-Chang Lin, Yu-Chih Lo, Hao Wu

Nature. Author manuscript; available in PMC 2010 Dec 1.

Published in final edited form as: Nature. 2010 Jun 17; 465(7300): 885–890. Published online 2010 May 19. doi: 10.1038/nature09121

PMCID:: PMC2888693

Abstract Article PDF–1.1M

Select item 26883969.

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

Horst von Bernuth, Capucine Picard, Zhongbo Jin, Rungnapa Pankla, Hui Xiao, Cheng-Lung Ku, Maya Chrabieh, Imen Ben Mustapha, Pegah Ghandil, Yildiz Camcioglu, Júlia Vasconcelos, Nicolas Sirvent, Margarida Guedes, Artur Bonito Vitor, María José Herrero-Mata, Juan Ignacio Aróstegui, Carlos Rodrigo, Laia Alsina, Estibaliz Ruiz-Ortiz, Manel Juan, Claudia Fortuny, Jordi Yagüe, Jordi Antón, Mariona Pascal, Huey-Hsuan Chang, Lucile Janniere, Yoann Rose, Ben-Zion Garty, Helen Chapel, Andrew Issekutz, László Maródi, Carlos Rodriguez-Gallego, Jacques Banchereau, Laurent Abel, Xiaoxia Li, Damien Chaussabel, Anne Puel, Jean-Laurent Casanova1

Science. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Science. 2008 Aug 1; 321(5889): 691–696. doi: 10.1126/science.1158298

PMCID:: PMC2688396

Abstract Article PDF–1.5M

Select item 257476610.

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Li Wen, Ruth E. Ley, Pavel V. Volchkov, Peter B. Stranges, Lia Avanesyan, Austin C. Stonebraker, Changyun Hu, F. Susan Wong, Gregory L. Szot, Jeffrey A. Bluestone, Jeffrey I. Gordon, Alexander V. Chervonsky

Nature. Author manuscript; available in PMC 2009 Apr 23.

Published in final edited form as: Nature. 2008 Oct 23; 455(7216): 1109–1113. Published online 2008 Sep 21. doi: 10.1038/nature07336

PMCID:: PMC2574766

Abstract Article PDF–743K

Select item 226878111.

T cell expression of MyD88 is required for resistance to Toxoplasma gondii

David F. LaRosa, Jason S. Stumhofer, Andrew E. Gelman, Adeeb H. Rahman, Devon K. Taylor, Christopher A. Hunter, Laurence A. Turka

Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3855–3860. Published online 2008 Feb 28. doi: 10.1073/pnas.0706663105

PMCID:: PMC2268781

Abstract Article PDF–1.8M

Select item 219380612.

Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4

Kimberly Burns, Sophie Janssens, Brian Brissoni, Natalia Olivos, Rudi Beyaert, Jürg Tschopp

J Exp Med. 2003 Jan 20; 197(2): 263–268. doi: 10.1084/jem.20021790

PMCID:: PMC2193806

Abstract Article PDF–154K

Select item 216904413.

FADD Negatively Regulates Lipopolysaccharide Signaling by Impairing Interleukin-1 Receptor-Associated Kinase 1-MyD88 Interaction

Rachel Zhande, Shauna M. Dauphinee, James A. Thomas, Masahiro Yamamoto, Shizuo Akira, Aly Karsan

Mol Cell Biol. 2007 Nov; 27(21): 7394–7404. Published online 2007 Sep 4. doi: 10.1128/MCB.00600-07

PMCID:: PMC2169044

Abstract Article PDF–573K

Select item 186839814.

Adjuvant-enhanced antibody responses occur without Toll-like receptor signaling

Amanda L. Gavin, Kasper Hoebe, Bao Duong, Takayuki Ota, Christopher Martin, Bruce Beutler, David Nemazee.

Science. Author manuscript; available in PMC 2007 May 14.

Published in final edited form as: Science. 2006 Dec 22; 314(5807): 1936–1938. doi: 10.1126/science.1135299

PMCID:: PMC1868398

Abstract Article PDF–271K

Select item 171620715.

Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

Sarah L. Brown, Terrence E. Riehl, Monica R. Walker, Michael J. Geske, Jason M. Doherty, William F. Stenson, Thaddeus S. Stappenbeck

J Clin Invest. 2007 Jan 2; 117(1): 258–269. Published online 2007 Jan 2. doi: 10.1172/JCI29159

PMCID:: PMC1716207

Abstract Article PDF–1.6M

Select item 53506416.

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88

Cecile M. Fremond, Vladimir Yeremeev, Delphine M. Nicolle, Muazzam Jacobs, Valerie F. Quesniaux, Bernhard Ryffel

J Clin Invest. 2004 Dec 15; 114(12): 1790–1799. doi: 10.1172/JCI21027

PMCID:: PMC535064

Abstract Article PDF–1.2M

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