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Select item 73108611.

Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3′UTR intron-containing NMD targets

Pooja Gangras, Thomas L. Gallagher, Michael A. Parthun, Zhongxia Yi, Robert D. Patton, Kiel T. Tietz, Natalie C. Deans, Ralf Bundschuh, Sharon L. Amacher, Guramrit Singh

PLoS Genet. 2020 Jun; 16(6): e1008830. Published online 2020 Jun 5. doi: 10.1371/journal.pgen.1008830

PMCID:: PMC7310861

Abstract Article PDF–5.1M

Select item 67833742.

Identification of a novel role for Foxo3 isoform2 in osteoclastic inhibition

Cheng Xu, Gregory J. Vitone, Kazuki Inoue, Courtney Ng, Baohong Zhao

J Immunol. Author manuscript; available in PMC 2020 Oct 15.

Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2141–2149. Published online 2019 Sep 20. doi: 10.4049/jimmunol.1900707

PMCID:: PMC6783374

Abstract Article PDF–1.5M

Select item 65414303.

FoxO3 activation in hypoxic tubules prevents chronic kidney disease

Ling Li, Huimin Kang, Qing Zhang, Vivette D. D’Agati, Qais Al-Awqati, Fangming Lin

J Clin Invest. 2019 Jun 3; 129(6): 2374–2389. Published online 2019 May 6. doi: 10.1172/JCI122256

PMCID:: PMC6541430

Abstract Article PDF–21M

Select item 52072654.

Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL)

Xing Liu, Xiaolian Cai, Bo Hu, Zhichao Mei, Dawei Zhang, Gang Ouyang, Jing Wang, Wei Zhang, Wuhan Xiao

J Biol Chem. 2016 Dec 2; 291(49): 25692–25705. Published online 2016 Oct 24. doi: 10.1074/jbc.M116.745471

PMCID:: PMC5207265

Abstract Article PDF–3.4M

Select item 37904575.

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

James C. Lee, Marion Espéli, Carl A. Anderson, Michelle A. Linterman, Joanna M. Pocock, Naomi J. Williams, Rebecca Roberts, Sebastien Viatte, Bo Fu, Norbert Peshu, Tran Tinh Hien, Nguyen Hoan Phu, Emma Wesley, Cathryn Edwards, Tariq Ahmad, John C. Mansfield, Richard Gearry, Sarah Dunstan, Thomas N. Williams, Anne Barton, Carola G. Vinuesa, UK IBD Genetics Consortium, Miles Parkes, Paul A. Lyons, Kenneth G.C. Smith

Cell. 2013 Sep 26; 155(1): 57–69. doi: 10.1016/j.cell.2013.08.034

PMCID:: PMC3790457

Abstract Article PDF–1.7M

Select item 37353496.

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Tadahiro Shimazu, Matthew D. Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A. Grueter, Hyungwook Lim, Laura R. Saunders, Robert D. Stevens, Christopher B. Newgard, Robert V. Farese, Jr., Rafael de Cabo, Scott Ulrich, Katerina Akassoglou, Eric Verdin

Science. Author manuscript; available in PMC 2013 Aug 6.

Published in final edited form as: Science. 2013 Jan 11; 339(6116): 211–214. Published online 2012 Dec 6. doi: 10.1126/science.1227166

PMCID:: PMC3735349

Abstract Article PDF–779K

Select item 36324367.

The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling

Carsten Skurk, Yasuhiro Izumiya, Henrike Maatz, Peter Razeghi, Ichiro Shiojima, Marco Sandri, Kaori Sato, Ling Zeng, Stephan Schiekofer, David Pimentel, Stewart Lecker, Heinrich Taegtmeyer, Alfred L. Goldberg, Kenneth Walsh

J Biol Chem. Author manuscript; available in PMC 2013 Apr 22.

Published in final edited form as: J Biol Chem. 2005 May 27; 280(21): 20814–20823. Published online 2005 Mar 21. doi: 10.1074/jbc.M500528200

PMCID:: PMC3632436

Abstract Article PDF–2.3M

Select item 35790028.

FoxO3a Directs a Protective Autophagy Program in Hematopoietic Stem Cells

Matthew R. Warr, Mikhail Binnewies, Johanna Flach, Damien Reynaud, Trit Garg, Ritu Malhotra, Jayanta Debnath, Emmanuelle Passegué

Nature. Author manuscript; available in PMC 2013 Aug 21.

Published in final edited form as: Nature. 2013 Feb 21; 494(7437): 323–327. Published online 2013 Feb 6. doi: 10.1038/nature11895

PMCID:: PMC3579002

Abstract Article PDF–635K

Select item 35569909.

A FOXO3/IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

Vladimir Litvak, Alexander V. Ratushny, Aaron E. Lampano, Frank Schmitz, Albert C. Huang, Ayush Raman, Alistair G. Rust, Andreas Bergthaler, John D. Aitchison, Alan Aderem

Nature. Author manuscript; available in PMC 2013 Apr 18.

Published in final edited form as: Nature. 2012 Oct 18; 490(7420): 421–425. Published online 2012 Sep 16. doi: 10.1038/nature11428

PMCID:: PMC3556990

Abstract Article PDF–834K

Select item 313143710.

FoxO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease

Jae-woong Hwang, Saravanan Rajendrasozhan, Hongwei Yao, Sangwoon Chung, Isaac K. Sundar, Heidie L. Huyck, Gloria S. Pryhuber, Vuokko L. Kinnula, Irfan Rahman

J Immunol. Author manuscript; available in PMC 2012 Jul 15.

Published in final edited form as: J Immunol. 2011 Jul 15; 187(2): 987–998. Published online 2011 Jun 20. doi: 10.4049/jimmunol.1001861

PMCID:: PMC3131437

Abstract Article PDF–2.0M

Select item 295468111.

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging

Kana Miyamoto, Takeshi Miyamoto, Reiko Kato, Akihiko Yoshimura, Noboru Motoyama, Toshio Suda

Blood. 2008 Dec 1; 112(12): 4485–4493. Prepublished online 2008 Sep 17. doi: 10.1182/blood-2008-05-159848

PMCID:: PMC2954681

Abstract Article

Select item 265402312.

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

Yang Mei, Yiru Zhang, Kazuo Yamamoto, Wei Xie, Tak W. Mak, Han You

Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13): 5153–5158. Published online 2009 Mar 10. doi: 10.1073/pnas.0901104106

PMCID:: PMC2654023

Abstract Article PDF–410K

Select item 263479813.

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

Miguel F. Segura, Douglas Hanniford, Silvia Menendez, Linsey Reavie, Xuanyi Zou, Silvia Alvarez-Diaz, Jan Zakrzewski, Elen Blochin, Amy Rose, Dusan Bogunovic, David Polsky, Jianjun Wei, Peng Lee, Ilana Belitskaya-Levy, Nina Bhardwaj, Iman Osman, Eva Hernando

Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6): 1814–1819. Published online 2009 Feb 2. doi: 10.1073/pnas.0808263106

PMCID:: PMC2634798

Abstract Article PDF–856K

Select item 254456614.

FOXO3A genotype is strongly associated with human longevity

Bradley J. Willcox, Timothy A. Donlon, Qimei He, Randi Chen, John S. Grove, Katsuhiko Yano, Kamal H. Masaki, D. Craig Willcox, Beatriz Rodriguez, J. David Curb

Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37): 13987–13992. Published online 2008 Sep 2. doi: 10.1073/pnas.0801030105

PMCID:: PMC2544566

Abstract Article PDF–253K

Select item 227638015.

FOXO3A Regulates Peroxiredoxin III Expression in Human Cardiac Fibroblasts

Calin B. Chiribau, Lihong Cheng, Ioan C. Cucoranu, Yong-Shen Yu, Roza E. Clempus, Dan Sorescu

J Biol Chem. 2008 Mar 28; 283(13): 8211–8217. doi: 10.1074/jbc.M710610200

PMCID:: PMC2276380

Abstract Article PDF–345K

Select item 217333916.

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B–enhanced cell survival through maintenance of mitochondrial integrity

Pascale F. Dijkers, Kim U. Birkenkamp, Eric W.-F. Lam, N. Shaun B. Thomas, Jan-Willem J. Lammers, Leo Koenderman, Paul J. Coffer

J Cell Biol. 2002 Feb 4; 156(3): 531–542. doi: 10.1083/jcb.200108084

PMCID:: PMC2173339

Abstract Article PDF–370K

Select item 217232317.

FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

Walbert J. Bakker, Montserrat Blázquez-Domingo, Andrea Kolbus, Janey Besooyen, Peter Steinlein, Hartmut Beug, Paul J. Coffer, Bob Löwenberg, Marieke von Lindern, Thamar B. van Dijk

J Cell Biol. 2004 Jan 19; 164(2): 175–184. doi: 10.1083/jcb.200307056

PMCID:: PMC2172323

Abstract Article PDF–344K

Select item 211842418.

Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4⁺ central memory T cells

Catherine Riou, Bader Yassine-Diab, Julien Van grevenynghe, Roland Somogyi, Larry D. Greller, Dominic Gagnon, Sylvain Gimmig, Peter Wilkinson, Yu Shi, Mark J. Cameron, Roberto Campos-Gonzalez, Robert S. Balderas, David Kelvin, Rafick-Pierre Sekaly, Elias K. Haddad

J Exp Med. 2007 Jan 22; 204(1): 79–91. doi: 10.1084/jem.20061681

PMCID:: PMC2118424

Abstract Article PDF–3.1M

Select item 193458719.

Foxo3 is required for the regulation of oxidative stress in erythropoiesis

Dragan Marinkovic, Xin Zhang, Safak Yalcin, Julia P. Luciano, Carlo Brugnara, Tara Huber, Saghi Ghaffari

J Clin Invest. 2007 Aug 1; 117(8): 2133–2144. Published online 2007 Aug 1. doi: 10.1172/JCI31807

PMCID:: PMC1934587

Abstract Article PDF–1.2M

Select item 185508920.

FoxOs are lineage-restricted redundant tumor suppressors and critical regulators of endothelial cell homeostasis

Ji-Hye Paik, Ramya Kollipara, Gerald Chu, Hongkai Ji, Yonghong Xiao, Zhihu Ding, Lili Miao, Zuzana Tothova, James W. Horner, Daniel R. Carrasco, Shan Jiang, D. Gary Gilliland, Lynda Chin, Wing H. Wong, Diego H. Castrillon, Ronald A. DePinho

Cell. Author manuscript; available in PMC 2008 Jan 26.

Published in final edited form as: Cell. 2007 Jan 26; 128(2): 309–323. doi: 10.1016/j.cell.2006.12.029

PMCID:: PMC1855089

Abstract Article PDF–1.7M

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PMC Links for OMIM (Select 602681) (21)
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Homo sapiens asteroid homolog 1 (Drosophila), mRNA (cDNA clone MGC:129980 IMAGE:...
Homo sapiens asteroid homolog 1 (Drosophila), mRNA (cDNA clone MGC:129980 IMAGE:40033986), complete cds
gi|115527462|gb|BC110616.2|

Nucleotide
Homo sapiens transmembrane 9 superfamily protein member 4, mRNA (cDNA clone MGC:...
Homo sapiens transmembrane 9 superfamily protein member 4, mRNA (cDNA clone MGC:31858 IMAGE:4896167), complete cds
gi|18089274|gb|BC021107.1|

Nucleotide
Pseudetroplus maculatus voucher GK144 brain-derived neurotrophic factor (BDNF) g...
Pseudetroplus maculatus voucher GK144 brain-derived neurotrophic factor (BDNF) gene, partial cds
gi|374115473|gb|JQ073157.1|

Nucleotide

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