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Items: 13

1.
η-Secretase processing of APP inhibits neuronal activity in the hippocampus
Michael Willem, Sabina Tahirovic, Marc Aurel Busche, Saak V. Ovsepian, Magda Chafai, Scherazad Kootar, Daniel Hornburg, Lewis D.B. Evans, Steven Moore, Anna Daria, Heike Hampel, Veronika Müller, Camilla Giudici, Brigitte Nuscher, Andrea Wenninger-Weinzierl, Elisabeth Kremmer, Michael T. Heneka, Dietmar R. Thal, Vilmantas Giedraitis, Lars Lannfelt, Ulrike Müller, Frederick J. Livesey, Felix Meissner, Jochen Herms, Arthur Konnerth, Hélène Marie, Christian Haass
Nature. Author manuscript; available in PMC 2019 Jun 14.
Published in final edited form as: Nature. 2015 Oct 15; 526(7573): 443–447. Published online 2015 Aug 31. doi: 10.1038/nature14864
PMCID:
PMC6570618
AbstractArticlePDF–1.7M
2.
Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes
Ying Du, Yingjun Zhao, Chuan Li, Qiuyang Zheng, Jing Tian, Zhuyi Li, Timothy Y. Huang, Wei Zhang, Huaxi Xu
J Exp Med. 2018 Jun 4; 215(6): 1665–1677. doi: 10.1084/jem.20171193
PMCID:
PMC5987914
AbstractArticlePDF–1.9M
3.
MicroRNA-339-5p Down-regulates Protein Expression of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (BACE1) in Human Primary Brain Cultures and Is Reduced in Brain Tissue Specimens of Alzheimer Disease Subjects
Justin M. Long, Balmiki Ray, Debomoy K. Lahiri
J Biol Chem. 2014 Feb 21; 289(8): 5184–5198. Published online 2013 Dec 18. doi: 10.1074/jbc.M113.518241
PMCID:
PMC3931075
AbstractArticlePDF–1.4M
4.
CutA Divalent Cation Tolerance Homolog (Escherichia coli) (CUTA) Regulates β-Cleavage of β-Amyloid Precursor Protein (APP) through Interacting with β-Site APP Cleaving Protein 1 (BACE1)
Yingjun Zhao, Yunshu Wang, Jin Hu, Xian Zhang, Yun-wu Zhang
J Biol Chem. 2012 Mar 30; 287(14): 11141–11150. Published online 2012 Feb 17. doi: 10.1074/jbc.M111.330209
PMCID:
PMC3322838
AbstractArticlePDF–1.7M
5.
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis
Farzaneh Modarresi, Mohammad Ali Faghihi, Nikunj S. Patel, Barbara G. Sahagan, Claes Wahlestedt, Miguel A. Lopez-Toledano
Int J Alzheimers Dis. 2011; 2011: 929042. Published online 2011 Jul 9. doi: 10.4061/2011/929042
PMCID:
PMC3139208
AbstractArticlePDF–5.6M
6.
Expression of a noncoding RNA is elevated in Alzheimer’s disease and drives rapid feed-forward regulation of ß-secretase expression
Mohammad Ali Faghihi, Farzaneh Modarresi, Ahmad M Khalil, Douglas E. Wood, Barbara G Sahagan, Todd E Morgan, Caleb E Finch, Georges St. Laurent, III, Paul J Kenny, Claes Wahlestedt
Nat Med. Author manuscript; available in PMC 2010 Feb 23.
Published in final edited form as: Nat Med. 2008 Jul; 14(7): 723–730. Published online 2008 Jun 29. doi: 10.1038/nm1784
PMCID:
PMC2826895
AbstractArticlePDF–2.4M
7.
COL25A1 triggers and promotes Alzheimer’s disease-like pathology in vivo
Ying Tong, Ying Xu, Kimberly Scearce-Levie, Louis J. Ptáček, Ying-Hui Fu
Neurogenetics. 2010; 11(1): 41–52. Published online 2009 Jun 23. doi: 10.1007/s10048-009-0201-5
PMCID:
PMC2807601
AbstractArticlePDF–771K
8.
BACE1 regulates voltage-gated sodium channels and neuronal activity
Doo Yeon Kim, Bryce W. Carey, Haibin Wang, Laura A. M. Ingano, Alexander M. Binshtok, Mary H. Wertz, Warren H. Pettingell, Ping He, Virginia M.-Y. Lee, Clifford J. Woolf, Dora M. Kovacs
Nat Cell Biol. Author manuscript; available in PMC 2009 Sep 21.
Published in final edited form as: Nat Cell Biol. 2007 Jul; 9(7): 755–764. Published online 2007 Jun 18. doi: 10.1038/ncb1602
PMCID:
PMC2747787
AbstractArticlePDF–2.4M
9.
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, Aikaterini S. Papadopoulou, Wim Mandemakers, Asli N. Silahtaroglu, Sakari Kauppinen, André Delacourte, Bart De Strooper
Proc Natl Acad Sci U S A. 2008 Apr 29; 105(17): 6415–6420. Published online 2008 Apr 23. doi: 10.1073/pnas.0710263105
PMCID:
PMC2359789
AbstractArticlePDF–946K
10.
BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo
Edward B. Lee, Bin Zhang, Kangning Liu, Eric A. Greenbaum, Robert W. Doms, John Q. Trojanowski, Virginia M.-Y. Lee
J Cell Biol. 2005 Jan 17; 168(2): 291–302. doi: 10.1083/jcb.200407070
PMCID:
PMC2171598
AbstractArticlePDF–3.9M
11.
Depletion of GGA3 stabilizes BACE and enhances ß-secretase activity
Giuseppina Tesco, Young Ho Koh, Eugene Kang, Andrew Cameron, Shinjita Das, Miguel Sena-Esteves, Mikko Hiltunen, Shao-Hua Yang, Zhenyu Zhong, Yong Shen, James Simpkins, Rudolph E. Tanzi
Neuron. Author manuscript; available in PMC 2008 Jun 7.
Published in final edited form as: Neuron. 2007 Jun 7; 54(5): 721–737. doi: 10.1016/j.neuron.2007.05.012
PMCID:
PMC1973166
AbstractArticlePDF–1.5M
12.
Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity
Huifang Ma, Sylvain Lesné, Linda Kotilinek, Jill V. Steidl-Nichols, Mathew Sherman, Linda Younkin, Steven Younkin, Colleen Forster, Nicolas Sergeant, André Delacourte, Robert Vassar, Martin Citron, Paulo Kofuji, Linda M. Boland, Karen H. Ashe
Proc Natl Acad Sci U S A. 2007 May 8; 104(19): 8167–8172. Published online 2007 Apr 30. doi: 10.1073/pnas.0609521104
PMCID:
PMC1859992
AbstractArticlePDF–1.0M
13.
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
Xiulian Sun, Guiqiong He, Hong Qing, Weihui Zhou, Frederick Dobie, Fang Cai, Matthias Staufenbiel, L. Eric Huang, Weihong Song
Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18727–18732. Published online 2006 Nov 22. doi: 10.1073/pnas.0606298103
PMCID:
PMC1693730
AbstractArticlePDF–932K

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