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Items: 5

1.
Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis
Yi Gong, Joon No Lee, Michael S. Brown, Joseph L. Goldstein, Jin Ye
Proc Natl Acad Sci U S A. 2006 Apr 18; 103(16): 6154–6159. Published online 2006 Apr 10. doi: 10.1073/pnas.0601923103
PMCID:
PMC1435366
AbstractArticlePDF–1.7M
2.
Schoenheimer effect explained – feedback regulation of cholesterol synthesis in mice mediated by Insig proteins
Luke J. Engelking, Guosheng Liang, Robert E. Hammer, Kiyosumi Takaishi, Hiroshi Kuriyama, Bret M. Evers, Wei-Ping Li, Jay D. Horton, Joseph L. Goldstein, Michael S. Brown
J Clin Invest. 2005 Sep 1; 115(9): 2489–2498. Published online 2005 Aug 11. doi: 10.1172/JCI25614
PMCID:
PMC1184040
AbstractArticlePDF–1.2M
3.
Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats
Kiyosumi Takaishi, Laurence Duplomb, May-Yun Wang, Jinping Li, Roger H. Unger
Proc Natl Acad Sci U S A. 2004 May 4; 101(18): 7106–7111. Published online 2004 Apr 19. doi: 10.1073/pnas.0401715101
PMCID:
PMC406473
AbstractArticlePDF–501K
4.
Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
Daisuke Yabe, Ryutaro Komuro, Guosheng Liang, Joseph L. Goldstein, Michael S. Brown
Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6): 3155–3160. Published online 2003 Mar 6. doi: 10.1073/pnas.0130116100
PMCID:
PMC152262
AbstractArticlePDF–256K
5.
Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
Daisuke Yabe, Michael S. Brown, Joseph L. Goldstein
Proc Natl Acad Sci U S A. 2002 Oct 1; 99(20): 12753–12758. Published online 2002 Sep 19. doi: 10.1073/pnas.162488899
PMCID:
PMC130532
AbstractArticlePDF–296K

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