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Select item 111596181.

Analysis of IDH1 and IDH2 mutations in Japanese glioma patients

Yukihiko Sonoda, Toshihiro Kumabe, Taigen Nakamura, Ryuta Saito, Masayuki Kanamori, Yoji Yamashita, Hiroyoshi Suzuki, Teiji Tominaga

Cancer Sci. 2009 Oct; 100(10): 1996–1998. Published online 2009 Sep 14. doi: 10.1111/j.1349-7006.2009.01270.x

PMCID:: PMC11159618

Abstract Article PDF–531K

Select item 111594482.

Genetic alterations and signaling pathways in the evolution of gliomas

Hiroko Ohgaki, Paul Kleihues

Cancer Sci. 2009 Dec; 100(12): 2235–2241. Published online 2009 Aug 6. doi: 10.1111/j.1349-7006.2009.01308.x

PMCID:: PMC11159448

Abstract Article PDF–418K

Select item 111315583.

Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart

G. Lin, R. W. Brownsey, K. M. MacLeod

Cell Mol Life Sci. 2009 Mar; 66(5): 919–932. Published online 2009 Jan 21. doi: 10.1007/s00018-009-8696-3

PMCID:: PMC11131558

Abstract Article PDF–1.7M

Select item 109462384.

Distribution and Functional Analysis of Isocitrate Dehydrogenases across Kinetoplastids

Ľubomíra Chmelová, Kristína Záhonová, Amanda T S Albanaz, Liudmyla Hrebenyk, Anton Horváth, Vyacheslav Yurchenko, Ingrid Škodová-Sveráková

Genome Biol Evol. 2024 Mar; 16(3): evae042. Published online 2024 Mar 6. doi: 10.1093/gbe/evae042

PMCID:: PMC10946238

Abstract Article PDF–734K

Select item 105740065.

Two Different Isocitrate Dehydrogenases from Pseudomonas aeruginosa: Enzymology and Coenzyme-Evolutionary Implications

Xuefei Chen, Wei Wei, Wei Xiong, Shen Wu, Quanchao Wu, Peng Wang, Guoping Zhu

Int J Mol Sci. 2023 Oct; 24(19): 14985. Published online 2023 Oct 7. doi: 10.3390/ijms241914985

PMCID:: PMC10574006

Abstract Article PDF–6.8M

Select item 100896366.

Capturing the Dynamic Conformational Changes of Human Isocitrate Dehydrogenase 1 (IDH1) upon Ligand and Metal Binding Using Hydrogen–Deuterium Exchange Mass Spectrometry

Kaitlyn A. Sabo, Elene Albekioni, Danielle Caliger, Nalani J. Coleman, Ella Thornberg, Diego Avellaneda Matteo, Elizabeth A. Komives, Steve Silletti, Christal D. Sohl

Biochemistry. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Biochemistry. 2023 Mar 21; 62(6): 1145–1159. Published online 2023 Feb 28. doi: 10.1021/acs.biochem.2c00636

PMCID:: PMC10089636

Abstract Article PDF–3.0M

Select item 99104407.

NADP(H)-dependent biocatalysis without adding NADP(H)

Ryan A. Herold, Raphael Reinbold, Christopher J. Schofield, Fraser A. Armstrong

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2214123120. Published online 2022 Dec 27. doi: 10.1073/pnas.2214123120

PMCID:: PMC9910440

Abstract Article PDF–3.2M

Select item 96379128.

Isocitrate binds to the itaconic acid–responsive LysR-type transcriptional regulator RipR in Salmonella pathogenesis

Nayeon Ki, Jinshil Kim, Inseong Jo, Yongseong Hyun, Sangryeol Ryu, Nam-Chul Ha

J Biol Chem. 2022 Nov; 298(11): 102562. Published online 2022 Oct 2. doi: 10.1016/j.jbc.2022.102562

PMCID:: PMC9637912

Abstract Article PDF–3.2M

Select item 94784569.

Isocitrate dehydrogenase 3b is required for spermiogenesis but dispensable for retinal viability

Siyan Zhu, Jiancheng Huang, Rong Xu, Yekai Wang, Yiming Wan, Rachel McNeel, Edward Parker, Douglas Kolson, Michelle Yam, Bradley Webb, Chen Zhao, Jenna Sigado, Jianhai Du

J Biol Chem. 2022 Sep; 298(9): 102387. Published online 2022 Aug 17. doi: 10.1016/j.jbc.2022.102387

PMCID:: PMC9478456

Abstract Article PDF–6.0M

Select item 920686810.

Tricarboxylic acid cycle related-metabolites and risk of atrial fibrillation and heart failure

Mònica Bulló, Christopher Papandreou, Jesus García-Gavilán, Miguel Ruiz-Canela, Jun Li, Marta Guasch-Ferré, Estefanía Toledo, Clary Clish, Dolores Corella, Ramon Estruch, Emilio Ros, Montserrat Fitó, Chih-Hao Lee, Kerry Pierce, Cristina Razquin, Fernando Arós, Lluís Serra-Majem, Liming Liang, Miguel A Martínez-González, Frank B Hu, Jordi Salas-Salvadó

Metabolism. Author manuscript; available in PMC 2022 Jun 19.

Published in final edited form as: Metabolism. 2021 Dec; 125: 154915. Published online 2021 Oct 20. doi: 10.1016/j.metabol.2021.154915

PMCID:: PMC9206868

Abstract Article PDF–360K

Select item 838561111.

Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function

Casey J. Bauchle, Kristen E. Rohli, Cierra K. Boyer, Vidhant Pal, Jonathan V. Rocheleau, Siming Liu, Yumi Imai, Eric B. Taylor, Samuel B. Stephens

Diabetes. 2021 Aug; 70(8): 1717–1728. Published online 2021 May 26. doi: 10.2337/db21-0037

PMCID:: PMC8385611

Abstract Article PDF–2.6M

Select item 809909112.

Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism

Sunghark Kwon, Hye Lin Chun, Hyun Ji Ha, So Yeon Lee, Hyun Ho Park

PLoS One. 2021; 16(5): e0251067. Published online 2021 May 5. doi: 10.1371/journal.pone.0251067

PMCID:: PMC8099091

Abstract Article PDF–2.3M

Select item 809469013.

PCR‐ and Restriction Endonuclease‐Based Detection of IDH1 Mutations

Jochen Meyer, Stefan Pusch, Jörg Balss, David Capper, Wolf Mueller, Arne Christians, Christian Hartmann, Andreas Von Deimling

Brain Pathol. 2010 Mar; 20(2): 298–300. Published online 2009 Aug 18. doi: 10.1111/j.1750-3639.2009.00327.x

PMCID:: PMC8094690

Abstract Article PDF–107K

Select item 809463614.

Characterization of R132H Mutation‐specific IDH1 Antibody Binding in Brain Tumors

David Capper, Susanne Weißert, Jörg Balss, Antje Habel, Jochen Meyer, Diana Jäger, Ulrike Ackermann, Claudia Tessmer, Andrey Korshunov, Hanswalter Zentgraf, Christian Hartmann, Andreas Von Deimling

Brain Pathol. 2010 Jan; 20(1): 245–254. Published online 2009 Oct 27. doi: 10.1111/j.1750-3639.2009.00352.x

PMCID:: PMC8094636

Abstract Article PDF–895K

Select item 809425715.

The Next Generation of Glioma Biomarkers: MGMT Methylation, BRAF Fusions and IDH1 Mutations

Andreas Von Deimling, Andrey Korshunov, Christian Hartmann

Brain Pathol. 2011 Jan; 21(1): 74–87. Published online 2010 Dec 3. doi: 10.1111/j.1750-3639.2010.00454.x

PMCID:: PMC8094257

Abstract Article PDF–756K

Select item 809406216.

Unraveling the Glioma Epigenome—From Molecular Mechanisms to Novel Biomarkers and Therapeutic Targets

Bastian Malzkorn, Marietta Wolter, Markus J. Riemenschneider, Guido Reifenberger

Brain Pathol. 2011 Nov; 21(6): 619–632. Published online 2011 Oct 13. doi: 10.1111/j.1750-3639.2011.00536.x

PMCID:: PMC8094062

Abstract Article PDF–308K

Select item 809296517.

Mutated IDH1 Is a Favorable Prognostic Factor for Type 2 Gliomatosis Cerebri

Mi Jung Kwon, Sung Tae Kim, Mi Jeong Kwon, Doo‐Sik Kong, Dageun Lee, Sanghui Park, So Young Kang, Ji‐Young Song, Do‐Hyun Nam, Yukinari Kato, Yoon‐La Choi, Yeon‐Lim Suh

Brain Pathol. 2012 May; 22(3): 307–317. Published online 2011 Nov 14. doi: 10.1111/j.1750-3639.2011.00532.x

PMCID:: PMC8092965

Abstract Article PDF–1.1M

Select item 805697118.

Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity

Jennifer M. Chambers, Wade Miller, Giovanni Quichocho, Viraj Upadhye, Diego Avellaneda Matteo, Andrey A. Bobkov, Christal D. Sohl, Jamie M. Schiffer

Biochemistry. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: Biochemistry. 2020 Feb 4; 59(4): 479–490. Published online 2020 Jan 13. doi: 10.1021/acs.biochem.9b01023

PMCID:: PMC8056971

Abstract Article PDF–1.5M

Select item 802885819.

Detection of 2‐Hydroxyglutarate in Formalin‐Fixed Paraffin‐Embedded Glioma Specimens by Gas Chromatography/Mass Spectrometry

Felix Sahm, David Capper, Stefan Pusch, Jörg Balss, Arend Koch, Claus‐Dieter Langhans, Jürgen G. Okun, Andreas von Deimling

Brain Pathol. 2012 Jan; 22(1): 26–31. Published online 2011 Aug 16. doi: 10.1111/j.1750-3639.2011.00506.x

PMCID:: PMC8028858

Abstract Article PDF–161K

Select item 799697020.

An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity

Lucas A. Luna, Zachary Lesecq, Katharine A. White, An Hoang, David A. Scott, Olga Zagnitko, Andrey A. Bobkov, Diane L. Barber, Jamie M. Schiffer, Daniel G. Isom, Christal D. Sohl

Biochem J. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Biochem J. 2020 Aug 28; 477(16): 2999–3018. doi: 10.1042/BCJ20200311

PMCID:: PMC7996970

Abstract Article PDF–1011K

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PMC Articles for PubChem Compound (Select 1198) (1216)
PMC
Mus musculus arachidonate 5-lipoxygenase (Alox5), mRNA
Mus musculus arachidonate 5-lipoxygenase (Alox5), mRNA
gi|116686109|ref|NM_009662.2|

Nucleotide
Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enric...
Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630103A12 product:TIP120-family protein TIP120B homolog [Rattus norvegicus], full insert sequence
gi|74215099|dbj|AK170420.1|

Nucleotide
Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched lib...
Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130033I21 product:hypothetical protein, full insert sequence
gi|74216589|dbj|AK164314.1|

Nucleotide
Mus musculus full open reading frame cDNA clone RZPDo836B0552D for gene 9030407H...
Mus musculus full open reading frame cDNA clone RZPDo836B0552D for gene 9030407H20Rik, RIKEN cDNA 9030407H20 gene; complete cds, incl. stopcodon
gi|71059934|emb|CT010303.1|

Nucleotide

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