PMC Articles for PubChem Compound (Select 24794418) - PMC

Select item 100192871.

Repurposing Axl Kinase Inhibitors for the Treatment of Respiratory Syncytial Virus Infection

Dan Zhang, Yuanhui Zhao, Xiaoxin You, Susu He, Erguang Li

Antimicrob Agents Chemother. 2023 Mar; 67(3): e01487-22. Published online 2023 Feb 28. doi: 10.1128/aac.01487-22

PMCID:: PMC10019287

Select item 75697202.

Detection and Therapeutic Implications of c-Met Mutations in Small Cell Lung Cancer and Neuroendocrine Tumors

J. Voortman, T. Harada, R.P. Chang, J.K. Killian, M. Suuriniemi, W.I. Smith, Jr, P.S. Meltzer, M. Lucchi, Y. Wang, G. Giaccone

Curr Pharm Des. Author manuscript; available in PMC 2020 Oct 19.

Published in final edited form as: Curr Pharm Des. 2013; 19(5): 833–840.

PMCID:: PMC7569720

Abstract Article PDF–1.3M

Select item 65557583.

Targeting of the AXL receptor tyrosine kinase by small molecule inhibitor leads to AXL cell surface accumulation by impairing the ubiquitin-dependent receptor degradation

Markus Lauter, Anja Weber, Robert Torka

Cell Commun Signal. 2019; 17: 59. Published online 2019 Jun 6. doi: 10.1186/s12964-019-0377-8

PMCID:: PMC6555758

Abstract Article PDF–1.3M

Select item 62716814.

Discovery of Novel c-Met Inhibitors Bearing a 3-Carboxyl Piperidin-2-one Scaffold

Wei Zhang, Jing Ai, Dakuo Shi, Xia Peng, Yinchun Ji, Jian Liu, Meiyu Geng, Yingxia Li

Molecules. 2014 Feb; 19(2): 2655–2673. Published online 2014 Feb 24. doi: 10.3390/molecules19022655

PMCID:: PMC6271681

Abstract Article PDF–528K

Select item 59279805.

RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

Alfia Khaibullina, Elena A. Adjei, Nowah Afangbedji, Andrey Ivanov, Namita Kumari, Luis E.F. Almeida, Zenaide M.N. Quezado, Sergei Nekhai, Marina Jerebtsova

Haematologica. 2018 May; 103(5): 787–798. Prepublished online 2018 Mar 8. doi: 10.3324/haematol.2017.180992

PMCID:: PMC5927980

Abstract Article PDF–4.2M

Select item 57716776.

RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis

Kelsi Andrade, Jaime Fornetti, Ling Zhao, Scott C. Miller, R. Lor Randall, Neysi Anderson, Susan E. Waltz, Mark McHale, Alana L. Welm

Sci Transl Med. Author manuscript; available in PMC 2018 Jan 17.

Published in final edited form as: Sci Transl Med. 2017 Jan 25; 9(374): eaai9338. doi: 10.1126/scitranslmed.aai9338

PMCID:: PMC5771677

Abstract Article PDF–1.5M

Select item 55286367.

Prevention of BMS‐777607‐induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics

Sharad Sharma, Hang-Ping Yao, Yong-Qing Zhou, Jianwei Zhou, Ruiwen Zhang, Ming-Hai Wang

Mol Oncol. 2014 May; 8(3): 469–482. Published online 2014 Jan 2. doi: 10.1016/j.molonc.2013.12.014

PMCID:: PMC5528636

Abstract Article PDF–3.3M

Select item 53749788.

Pharmacologic targeting of S6K1 in PTEN-deficient neoplasia

Hongqi Liu, Xizhi Feng, Kelli N. Ennis, Catherine A. Behrmann, Pranjal Sarma, Tony T. Jiang, Satoshi Kofuji, Liang Niu, Yiwen Stratton, Hala Elnakat Thomas, Sang-Oh Yoon, Atsuo T. Sasaki, David R. Plas

Cell Rep. Author manuscript; available in PMC 2017 Mar 31.

Published in final edited form as: Cell Rep. 2017 Feb 28; 18(9): 2088–2095. doi: 10.1016/j.celrep.2017.02.022

PMCID:: PMC5374978

Abstract Article PDF–1.2M

Select item 48910909.

Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo

Julia Onken, Robert Torka, Sören Korsing, Josefine Radke, Irina Krementeskaia, Melina Nieminen, Xi Bai, Axel Ullrich, Frank Heppner, Peter Vajkoczy

Oncotarget. 2016 Mar 1; 7(9): 9876–9889. Published online 2016 Feb 2. doi: 10.18632/oncotarget.7130

PMCID:: PMC4891090

Abstract Article PDF–11M

Select item 442833310.

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Judith Müller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patricia A. Possik, Paulien D.M. Cornelissen-Steijger, Marnix H. Geukes Foppen, Kristel Kemper, Colin R. Goding, Ultan McDermott, Christian Blank, John Haanen, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Daniel S. Peeper

Nat Commun. Author manuscript; available in PMC 2015 May 12.

Published in final edited form as: Nat Commun. 2014; 5: 5712. Published online 2014 Dec 15. doi: 10.1038/ncomms6712

PMCID:: PMC4428333

Abstract Article PDF–2.5M

Select item 341857211.

Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607

Yao Dai, Dietmar W Siemann

BMC Cancer. 2012; 12: 198. Published online 2012 May 28. doi: 10.1186/1471-2407-12-198

PMCID:: PMC3418572

Abstract Article PDF–1.1M

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