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Select item 99132461.

Genes Involved in DNA Repair and Mitophagy Protect Embryoid Bodies from the Toxic Effect of Methylmercury Chloride under Physioxia Conditions

Justyna Augustyniak, Hanna Kozlowska, Leonora Buzanska

Cells. 2023 Feb; 12(3): 390. Published online 2023 Jan 21. doi: 10.3390/cells12030390

PMCID:: PMC9913246

Abstract Article PDF–4.2M

Select item 88096652.

Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study

Qi Qiu, Yali Huang, Bei Zhang, Doudou Huang, Xin Chen, Zhongxiong Fan, Jinpei Lin, Wensheng Yang, Kai Wang, Ning Qu, Juan Li, Zhihong Li, Jingyu Huang, Shenrui Li, Jiaxing Zhang, Gang Liu, Gang Rui, Xiaoyuan Chen, Qingliang Zhao

Environ Health Perspect. 2022 Feb; 130(2): 027002. Published online 2022 Feb 2. doi: 10.1289/EHP8907

PMCID:: PMC8809665

Abstract Article PDF–3.4M

Select item 87613913.

Environmentally Relevant Developmental Methylmercury Exposures Alter Neuronal Differentiation in a Human-Induced Pluripotent Stem Cell Model

Lisa M. Prince, M. Diana Neely, Emily B. Warren, Morgan G. Thomas, Madeline R. Henley, Kiara K. Smith, Michael Aschner, Aaron B. Bowman

Food Chem Toxicol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Food Chem Toxicol. 2021 Jun; 152: 112178. Published online 2021 Apr 5. doi: 10.1016/j.fct.2021.112178

PMCID:: PMC8761391

Abstract Article PDF–2.5M

Select item 87613904.

Single cell RNA sequencing detects persistent cell type- and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model

M. Diana Neely, Shaojun Xie, Lisa M. Prince, Hyunjin Kim, Anke M. Tukker, Michael Aschner, Jyothi Thimmapuram, Aaron B. Bowman

Food Chem Toxicol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Food Chem Toxicol. 2021 Aug; 154: 112288. Published online 2021 Jun 2. doi: 10.1016/j.fct.2021.112288

PMCID:: PMC8761390

Abstract Article PDF–1.0M

Select item 86339035.

Neuroligin-1 Is a Mediator of Methylmercury Neuromuscular Toxicity

Jakob T Gunderson, Ashley E Peppriell, Ian N Krout, Daria Vorojeikina, Matthew D Rand

Toxicol Sci. 2021 Dec; 184(2): 236–251. Published online 2021 Sep 21. doi: 10.1093/toxsci/kfab114

PMCID:: PMC8633903

Abstract Article PDF–1.2M

Select item 85229616.

Combining in vitro assays and mathematical modelling to study developmental neurotoxicity induced by chemical mixtures

Francesca Pistollato, Donatella Carpi, Emilio Mendoza-de Gyves, Alicia Paini, Stephanie K. Bopp, Andrew Worth, Anna Bal-Price

Reprod Toxicol. 2021 Oct; 105: 101–119. doi: 10.1016/j.reprotox.2021.08.007

PMCID:: PMC8522961

Abstract Article

Select item 83239917.

Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells

Bai Li, Cunye Qiao, Xiaolei Jin, Hing Man Chan

Environ Health Perspect. 2021 Jul; 129(7): 077007. Published online 2021 Jul 30. doi: 10.1289/EHP7349

PMCID:: PMC8323991

Abstract Article PDF–6.8M

Select item 81105828.

Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang

Sci Rep. 2021; 11: 9832. Published online 2021 May 10. doi: 10.1038/s41598-021-89210-7

PMCID:: PMC8110582

Abstract Article PDF–2.3M

Select item 78601699.

Chronic Exposure to Methylmercury Enhances the Anorexigenic Effects of Leptin in C57BL/6J Male Mice

Beatriz Ferrer, Lisa M Prince, Alexey A Tinkov, Abel Santamaria, Marcelo Farina, João Batista Rocha, Aaron B Bowman, Michael Aschner

Food Chem Toxicol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Food Chem Toxicol. 2021 Jan; 147: 111924. Published online 2020 Dec 15. doi: 10.1016/j.fct.2020.111924

PMCID:: PMC7860169

Abstract Article PDF–3.8M

Select item 776573010.

The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity

Zhi-Bin Tong, John Braisted, Pei-Hsuan Chu, David Gerhold

Neurotox Res. Author manuscript; available in PMC 2020 Dec 26.

Published in final edited form as: Neurotox Res. 2020 Dec; 38(4): 967–978. Published online 2020 Sep 1. doi: 10.1007/s12640-020-00272-3

PMCID:: PMC7765730

Abstract Article PDF–1.1M

Select item 770844411.

AMPA RECEPTOR CONTRIBUTION TO METHYLMERCURY-MEDIATED ALTERATION OF INTRACELLULAR Ca²⁺ CONCENTRATION IN HUMAN INDUCED PLURIPOTENT STEM CELL MOTOR NEURONS

Alexandra Colón-Rodríguez, Nicole M. Colón-Carrión, William D. Atchison

Neurotoxicology. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Neurotoxicology. 2020 Dec; 81: 116–126. Published online 2020 Sep 28. doi: 10.1016/j.neuro.2020.09.037

PMCID:: PMC7708444

Abstract Article PDF–2.1M

Select item 770841012.

Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice.

Matthew D. Rand, Katherine Conrad, Elena Marvin, Katherine Harvey, Don Henderson, Rabi Tawil, Marissa Sobolewski, Deborah A. Cory-Slechta

Neurotoxicology. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Neurotoxicology. 2020 Dec; 81: 1–10. Published online 2020 Jul 28. doi: 10.1016/j.neuro.2020.07.007

PMCID:: PMC7708410

Abstract Article PDF–782K

Select item 753009313.

Methylmercury myotoxicity targets formation of the myotendinous junction

Ashley E. Peppriell, Jakob T. Gunderson, Daria Vorojeikina, Matthew D. Rand

Toxicology. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Toxicology. 2020 Oct; 443: 152561. Published online 2020 Aug 13. doi: 10.1016/j.tox.2020.152561

PMCID:: PMC7530093

Abstract Article PDF–1.1M

Select item 707324614.

Trends in Neurodevelopmental Disability Burden due to Early Life Chemical Exposure in the USA from 2001 to 2016: A Population-Based Disease Burden and Cost Analysis

Abigail Gaylord, Gwendolyn Osborne, Akhgar Ghassabian, Julia Malits, Teresa Attina, Leonardo Trasande

Mol Cell Endocrinol. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Mol Cell Endocrinol. 2020 Feb 15; 502: 110666. Published online 2020 Jan 14. doi: 10.1016/j.mce.2019.110666

PMCID:: PMC7073246

Abstract Article PDF–289K

Select item 703700715.

Understanding the Solution Behavior of Epinephrine in the Presence of Toxic Cations: A Thermodynamic Investigation in Different Experimental Conditions

Francesco Crea, Concetta De Stefano, Anna Irto, Gabriele Lando, Stefano Materazzi, Demetrio Milea, Alberto Pettignano, Silvio Sammartano

Molecules. 2020 Feb; 25(3): 511. Published online 2020 Jan 24. doi: 10.3390/molecules25030511

PMCID:: PMC7037007

Abstract Article PDF–3.1M

Select item 702743316.

Methylmercury modifies temporally expressed myogenic regulatory factors to inhibit myoblast differentiation

Megan Culbreth, Matthew D. Rand

Toxicol In Vitro. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Toxicol In Vitro. 2020 Mar; 63: 104717. Published online 2019 Nov 6. doi: 10.1016/j.tiv.2019.104717

PMCID:: PMC7027433

Abstract Article PDF–747K

Select item 701700317.

The Nuclear Protein HOXB13 Enhances Methylmercury Toxicity by Inducing Oncostatin M and Promoting Its Binding to TNFR3 in Cultured Cells

Takashi Toyama, Sidi Xu, Ryo Nakano, Takashi Hasegawa, Naoki Endo, Tsutomu Takahashi, Jin-Yong Lee, Akira Naganuma, Gi-Wook Hwang

Cells. 2020 Jan; 9(1): 45. Published online 2019 Dec 23. doi: 10.3390/cells9010045

PMCID:: PMC7017003

Abstract Article PDF–2.9M

Select item 695727818.

Acute Methylmercury Exposure and the Hypoxia-Inducible equation m1

Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro

Jie Chang, Bobo Yang, Yun Zhou, Changsheng Yin, Tingting Liu, Hai Qian, Guangwei Xing, Suhua Wang, Fang Li, Yubin Zhang, Da Chen, Michael Aschner, Rongzhu Lu

Environ Health Perspect. 2019 Dec; 127(12): 127006. Published online 2019 Dec 18. doi: 10.1289/EHP5139

PMCID:: PMC6957278

Abstract Article PDF–1.9M

Select item 692145619.

Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses

Bruna Candia Piccoli, Ana Lúcia Anversa Segatto, Cláudia Sirlene Oliveira, Fernanda D’Avila da Silva, Michael Aschner, João Batista Teixeira da Rocha

BMC Pharmacol Toxicol. 2019; 20(Suppl 1): 83. Published online 2019 Dec 19. doi: 10.1186/s40360-019-0356-0

PMCID:: PMC6921456

Abstract Article PDF–2.6M

Select item 671013420.

Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ

Bobo Yang, Changsheng Yin, Yun Zhou, Qiang Wang, Yuanyue Jiang, Yu Bai, Hai Qian, Guangwei Xing, Suhua Wang, Fang Li, Yun Feng, Yubin Zhang, Jiyang Cai, Aschner Michael, Rongzhu Lu

Toxicology. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Toxicology. 2019 Sep 1; 425: 152248. Published online 2019 Jul 19. doi: 10.1016/j.tox.2019.152248