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Select item 112120081.

Development of a New DHFR-Based Destabilizing Domain with Enhanced Basal Turnover and Applicability in Mammalian Systems

Emi Nakahara, Vishruth Mullapudi, Gracen E. Collier, Lukasz A. Joachimiak, John D. Hulleman

ACS Chem Biol. Author manuscript; available in PMC 2024 Jun 28.

Published in final edited form as: ACS Chem Biol. 2022 Oct 21; 17(10): 2877–2889. Published online 2022 Sep 19. doi: 10.1021/acschembio.2c00518

PMCID:: PMC11212008

Abstract Article PDF–2.3M

Select item 110052902.

Serotype diversity and antimicrobial susceptibility profiles of Actinobacillus pleuropneumoniae isolated in Italian pig farms from 2015 to 2022

Flavia Guarneri, Claudia Romeo, Federico Scali, Simona Zoppi, Nicoletta Formenti, Antonio Marco Maisano, Salvatore Catania, Marcelo Gottschalk, G. Loris Alborali

Vet Res. 2024; 55: 48. Published online 2024 Apr 9. doi: 10.1186/s13567-024-01305-x

PMCID:: PMC11005290

Abstract Article PDF–1.4M

Select item 109849263.

Development and validation of an UPLC–MS/MS assay for the simultaneous quantification of seven commonly used antibiotics in human plasma and its application in therapeutic drug monitoring

Xin Meng Mekking, Kirsten Velthoven-Graafland, Marga J A Teulen, Roger J M Brüggemann, Lindsey H M te Brake, Nynke G L Jager

J Antimicrob Chemother. 2024 Apr; 79(4): 883–890. Published online 2024 Feb 28. doi: 10.1093/jac/dkae047

PMCID:: PMC10984926

Abstract Article PDF–356K

Select item 108896754.

Antibiotic Combination to Effectively Postpone or Inhibit the In Vitro Induction and Selection of Levofloxacin-Resistant Mutants in Elizabethkingia anophelis

Ching-Chi Lee, Chung-Hsu Lai, Chih-Hui Yang, Yi-Han Huang, Jiun-Nong Lin

Int J Mol Sci. 2024 Feb; 25(4): 2215. Published online 2024 Feb 12. doi: 10.3390/ijms25042215

PMCID:: PMC10889675

Abstract Article PDF–976K

Select item 108829935.

Protecting the Achilles heel: three FolE_I-type GTP-cyclohydrolases needed for full growth of metal-resistant Cupriavidus metallidurans under a variety of conditions

Vladislava Schulz, Diana Galea, Martin Herzberg, Dietrich H. Nies

J Bacteriol. 2024 Feb; 206(2): e00395-23. Published online 2024 Jan 16. doi: 10.1128/jb.00395-23

PMCID:: PMC10882993

Abstract Article PDF–5.7M

Select item 108516036.

Regulation of overexpressed efflux pump encoding genes by cinnamon oil and trimethoprim to abolish carbapenem-resistant Acinetobacter baumannii clinical strains

Neveen M. Saleh, Hadeer Ezzat, Gharieb S. El-Sayyad, Hamdallah Zedan

BMC Microbiol. 2024; 24: 52. Published online 2024 Feb 8. doi: 10.1186/s12866-024-03194-8

PMCID:: PMC10851603

Abstract Article PDF–2.6M

Select item 108390707.

Invasive Streptococcus suis isolated in Spain contain a highly promiscuous and dynamic resistome

Cristina Uruén, Jorge Gimeno, Marina Sanz, Lorenzo Fraile, Clara M. Marín, Jesús Arenas

Front Cell Infect Microbiol. 2023; 13: 1329632. Published online 2024 Jan 22. doi: 10.3389/fcimb.2023.1329632

PMCID:: PMC10839070

Abstract Article PDF–11M

Select item 107863688.

Clarification of adverse drug reactions by a pharmacovigilance team results in increased antibiotic re-prescribing at a freestanding United States children’s hospital

Keith Feldman, Sarah L. Suppes, Jennifer L. Goldman

PLoS One. 2024; 19(1): e0295410. Published online 2024 Jan 12. doi: 10.1371/journal.pone.0295410

PMCID:: PMC10786368

Abstract Article PDF–1.4M

Select item 107778559.

Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus

Wassihun Wedajo Aragaw, Dereje A. Negatu, Christopher J. Bungard, Véronique A. Dartois, Abdellatif El Marrouni, Elliott B. Nickbarg, David B. Olsen, Ralf Warrass, Thomas Dick

Antimicrob Agents Chemother. 2024 Jan; 68(1): e00717-23. Published online 2023 Nov 29. doi: 10.1128/aac.00717-23

PMCID:: PMC10777855

Abstract Article PDF–1.3M

Select item 1074625510.

Pervasive gene deregulation underlies adaptation and maladaptation in trimethoprim-resistant E. coli

Rhea Vinchhi, Chetna Yelpure, Manasvi Balachandran, Nishad Matange

mBio. 2023 Nov-Dec; 14(6): e02119-23. Published online 2023 Nov 30. doi: 10.1128/mbio.02119-23

PMCID:: PMC10746255

Abstract Article PDF–3.7M

Select item 1071478311.

Construction and functional verification of size-reduced plasmids based on TMP resistance gene dfrB10

Chun-cao Li, Rui Hu, Xiu-min Hua, Yi-xuan Ni, Lu Ge, Lu Zhang, Wen Yu, Ni-xin Hao, Hui Xia, Qiang Fang, Zhi-yong Tao

Microbiol Spectr. 2023 Nov-Dec; 11(6): e01206-23. Published online 2023 Oct 31. doi: 10.1128/spectrum.01206-23

PMCID:: PMC10714783

Abstract Article PDF–911K

Select item 1069896312.

Chest wall abscess and costochondritis due to Salmonella enterica serotype Choleraesuis: a case report

Nassim R. Mokraoui, Rose Ganim, Armando Paez

J Med Case Rep. 2023; 17: 502. Published online 2023 Dec 6. doi: 10.1186/s13256-023-04229-w

PMCID:: PMC10698963

Abstract Article PDF–1.8M

Select item 1062468913.

Regulation of eDHFR-tagged proteins with trimethoprim PROTACs

Jean M. Etersque, Iris K. Lee, Nitika Sharma, Kexiang Xu, Andrew Ruff, Justin D. Northrup, Swarbhanu Sarkar, Tommy Nguyen, Richard Lauman, George M. Burslem, Mark A. Sellmyer

Nat Commun. 2023; 14: 7071. Published online 2023 Nov 3. doi: 10.1038/s41467-023-42820-3

PMCID:: PMC10624689

Abstract Article PDF–2.2M

Select item 1054436614.

Epidemiology and clinical characteristics of patients with carbapenem-resistant enterobacterales infections: experience from a large tertiary care center in a developing country

Banan M. Aiesh, Yazan Maali, Farah Qandeel, Siwar Omarya, Shatha Abu Taha, Suha Sholi, Ali Sabateen, Adham Abu Taha, Sa’ed H. Zyoud

BMC Infect Dis. 2023; 23: 644. Published online 2023 Oct 2. doi: 10.1186/s12879-023-08643-9

PMCID:: PMC10544366

Abstract Article PDF–1.1M

Select item 1047505315.

Optimization of process parameters for trimethoprim and sulfamethoxazole removal by magnetite-chitosan nanoparticles using Box–Behnken design

Mahsa Alishiri, Maryam Gonbadi, Mehdi Narimani, Seyyed Amirreza Abdollahi, Negin Shahsavaripour

Sci Rep. 2023; 13: 14489. Published online 2023 Sep 2. doi: 10.1038/s41598-023-41823-w

PMCID:: PMC10475053

Abstract Article PDF–1.9M

Select item 1043240116.

Trimethoprim resistance in surface and wastewater is mediated by contrasting variants of the dfrB gene

David Kneis, Claudèle Lemay-St-Denis, Stella Cellier-Goetghebeur, Alan X. Elena, Thomas U. Berendonk, Joelle N. Pelletier, Stefanie Heß

ISME J. 2023 Sep; 17(9): 1455–1466. Published online 2023 Jun 27. doi: 10.1038/s41396-023-01460-7

PMCID:: PMC10432401

Abstract Article PDF–1.1M

Select item 1042821417.

Kinetic Barrier to Enzyme Inhibition Is Manipulated by Dynamical Local Interactions in E. coli DHFR

Ebru Cetin, Tandac F. Guclu, Isik Kantarcioglu, Ilona K. Gaszek, Erdal Toprak, Ali Rana Atilgan, Burcu Dedeoglu, Canan Atilgan

J Chem Inf Model. 2023 Aug 14; 63(15): 4839–4849. Published online 2023 Jul 26. doi: 10.1021/acs.jcim.3c00818

PMCID:: PMC10428214

Abstract Article PDF–5.6M

Select item 1040469718.

Red osier dogwood extract versus Trimethoprim-sulfadiazine (Part 1). Effects on the growth performance, blood parameters, gut histomorphometry, and Salmonella excretion of broiler chickens orally challenged with Salmonella Enteritidis

Taiwo J. Erinle, Martine Boulianne, Deborah I. Adewole

Poult Sci. 2023 Aug; 102(8): 102723. Published online 2023 Apr 15. doi: 10.1016/j.psj.2023.102723

PMCID:: PMC10404697

Abstract Article PDF–369K

Select item 1028154019.

Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking

Komgrit Eawsakul, Deepak Parajuli, Nattarat Wongsuwan, Norased Nasongkla

Exp Biol Med (Maywood) 2023 Mar; 248(6): 481–491. Published online 2023 Feb 22. doi: 10.1177/15353702231151984

PMCID:: PMC10281540

Abstract Article PDF–1.3M

Select item 1028094120.

A double-blinded randomized placebo-controlled non-inferiority trial protocol for postoperative infections associated with canine pyometra

Anna Ylhäinen, Sari Mölsä, Thomas Grönthal, Jouni Junnila, Merja Rantala, Outi Laitinen-Vapaavuori, Katariina Thomson

BMC Vet Res. 2023; 19: 77. Published online 2023 Jun 20. doi: 10.1186/s12917-023-03629-w

PMCID:: PMC10280941

Abstract Article PDF–1.6M

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PMC Articles for PubChem Compound (Select 5578) (1690)
PMC
phospholipid phosphatase 5 isoform 4 [Homo sapiens]
phospholipid phosphatase 5 isoform 4 [Homo sapiens]
gi|1237937843|ref|NP_001341381.1|

Protein
phospholipid phosphatase 5 isoform X4 [Homo sapiens]
phospholipid phosphatase 5 isoform X4 [Homo sapiens]
gi|2217373488|ref|XP_011542977.2|

Protein

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