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Select item 38330891.

Natamycin and voriconazole in Fusarium and Aspergillus keratitis: subgroup analysis of a randomised controlled trial

Venkatesh N Prajna, Prajna S Lalitha, Jeena Mascarenhas, Tiruvengada Krishnan, Muthiah Srinivasan, C M Vaitilingam, Catherine E Oldenburg, Aileen Sy, Jeremy David Keenan, Travis C Porco, Nisha R Acharya, Thomas M Lietman

Br J Ophthalmol. Author manuscript; available in PMC 2013 Nov 19.

Published in final edited form as: Br J Ophthalmol. 2012 Nov; 96(11): 10.1136/bjophthalmol-2012-301825. Published online 2012 Aug 21. doi: 10.1136/bjophthalmol-2012-301825

PMCID:: PMC3833089

Article PDF–29K

Select item 38305522.

Gender differences in re-epithelialisation time in fungal corneal ulcers

Tiruvengada Krishnan, N Venkatesh Prajna, Karsten Gronert, Catherine E Oldenburg, Kathryn J Ray, Jeremy D Keenan, Thomas M Lietman, Nisha R Acharya

Br J Ophthalmol. Author manuscript; available in PMC 2013 Nov 16.

Published in final edited form as: Br J Ophthalmol. 2012 Jan; 96(1): 10.1136/bjophthalmol-2011-300441. Published online 2011 Oct 6. doi: 10.1136/bjophthalmol-2011-300441

PMCID:: PMC3830552

Article PDF–29K

Select item 38305503.

Amphotericin B and natamycin are not synergistic in vitro against Fusarium and Aspergillus spp. isolated from keratitis

Prajna Lalitha, Brett L. Shapiro, Allison R. Loh, Annette W. Fothergill, N. Venkatesh Prajna, M. Srinivasan, Catherine E. Oldenburg, David A. Quigley, Jaya D. Chidambaram, Stephen D. McLeod, Nisha R. Acharya, Thomas M. Lietman

Br J Ophthalmol. Author manuscript; available in PMC 2013 Nov 16.

Published in final edited form as: Br J Ophthalmol. 2011 May; 95(5): 10.1136/bjo.2010.195214. Published online 2010 Oct 28. doi: 10.1136/bjo.2010.195214

PMCID:: PMC3830550

Article PDF–339K

Select item 38080914.

Antifungal Tradecraft by Cholesterol Oxidase

Natasha M. Nesbitt, Nicole S. Sampson

Chem Biol. Author manuscript; available in PMC 2013 Oct 25.

Published in final edited form as: Chem Biol. 2007 Mar; 14(3): 10.1016/j.chembiol.2007.03.003. doi: 10.1016/j.chembiol.2007.03.003

PMCID:: PMC3808091

Abstract Article PDF–194K

Select item 37741265.

Comparison of Natamycin and Voriconazole for the Treatment of Fungal Keratitis

Dr Namperumalsamy V. Prajna, Dr Jeena Mascarenhas, Dr Tiruvengada Krishnan, Dr P. Ravindranath Reddy, Dr Lalitha Prajna, Dr Muthiah Srinivasan, Mr C. M. Vaitilingam, Mr Kevin C. Hong, Dr Salena M. Lee, Dr Stephen D. McLeod, Dr Michael E. Zegans, Dr Travis C. Porco, Dr Thomas M. Lietman, Dr Nisha R. Acharya

Arch Ophthalmol. Author manuscript; available in PMC 2013 Sep 16.

Published in final edited form as: Arch Ophthalmol. 2010 Jun; 128(6): 672–678. doi: 10.1001/archophthalmol.2010.102

PMCID:: PMC3774126

Abstract Article PDF–926K

Select item 37692116.

The Mycotic Ulcer Treatment Trial: A Randomized Trial Comparing Natamycin vs Voriconazole

Dr. N. Venkatesh Prajna, Dr. Tiruvengada Krishnan, Dr. Jeena Mascarenhas, Dr. Revathi Rajaraman, Dr. Lalitha Prajna, Dr. Muthiah Srinivasan, Dr. Anita Raghavan, Ms. Catherine E. Oldenburg, Ms. Kathryn J. Ray, Dr. Michael E. Zegans, Dr. Stephen D. McLeod, Dr. Travis C. Porco, Dr. Nisha R. Acharya, Dr. Thomas M. Lietman

JAMA Ophthalmol. Author manuscript; available in PMC 2013 Sep 10.

Published in final edited form as: JAMA Ophthalmol. 2013 Apr; 131(4): 422–429. doi: 10.1001/jamaophthalmol.2013.1497

PMCID:: PMC3769211

Abstract Article PDF–754K

Select item 36957377.

Organism, MIC, and Outcome in a Fungal Corneal Ulcer Clinical Trial

Prajna Lalitha, N. Venkatesh Prajna, Catherine E. Oldenburg, Muthiah Srinivasan, Tiruvengada Krishnan, Jeena Mascarenhas, C.M. Vaitilingam, Stephen D. McLeod, Michael E. Zegans, Travis C. Porco, Nisha R. Acharya, Thomas M. Lietman

Cornea. Author manuscript; available in PMC 2013 Jun 28.

Published in final edited form as: Cornea. 2012 Jun; 31(6): 662–667. doi: 10.1097/ICO.0b013e31823f8ae0

PMCID:: PMC3695737

Abstract Article PDF–314K

Select item 34438448.

Predictors of outcome in fungal keratitis

N Venkatesh Prajna, T Krishnan, J Mascarenhas, M Srinivasan, C E Oldenburg, C M Toutain-Kidd, A Sy, S D McLeod, M E Zegans, N R Acharya, T M Lietman, T C Porco

Eye (Lond) 2012 Sep; 26(9): 1226–1231. Published online 2012 Jun 29. doi: 10.1038/eye.2012.99

PMCID:: PMC3443844

Abstract Article PDF–257K

Select item 33964789.

Polyene antibiotic that inhibits membrane transport proteins

Yvonne Maria te Welscher, Martin Richard van Leeuwen, Ben de Kruijff, Jan Dijksterhuis, Eefjan Breukink

Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11156–11159. Published online 2012 Jun 25. doi: 10.1073/pnas.1203375109

PMCID:: PMC3396478

Abstract Article PDF–311K

Select item 339468610.

Characterization of Fusarium Keratitis Outbreak Isolates: Contribution of Biofilms to Antimicrobial Resistance and Pathogenesis

Pranab K. Mukherjee, Jyotsna Chandra, Changping Yu, Yan Sun, Eric Pearlman, Mahmoud A. Ghannoum

Invest Ophthalmol Vis Sci. 2012 Jul; 53(8): 4450–4457. Published online 2012 Jul 3. doi: 10.1167/iovs.12-9848

PMCID:: PMC3394686

Abstract Article PDF–3.2M

Select item 336793211.

Hierarchical Control on Polyene Macrolide Biosynthesis: PimR Modulates Pimaricin Production via the PAS-LuxR Transcriptional Activator PimM

Javier Santos-Aberturas, Cláudia M. Vicente, Tamara D. Payero, Lara Martín-Sánchez, Carmen Cañibano, Juan F. Martín, Jesús F. Aparicio

PLoS One. 2012; 7(6): e38536. Published online 2012 Jun 5. doi: 10.1371/journal.pone.0038536

PMCID:: PMC3367932

Abstract Article PDF–1.7M

Select item 321966212.

Crosstalk between ROS Homeostasis and Secondary Metabolism in S. natalensis ATCC 27448: Modulation of Pimaricin Production by Intracellular ROS

Tiago Beites, Sílvia D. S. Pires, Catarina L. Santos, Hugo Osório, Pedro Moradas-Ferreira, Marta V. Mendes

PLoS One. 2011; 6(11): e27472. Published online 2011 Nov 17. doi: 10.1371/journal.pone.0027472

PMCID:: PMC3219662

Abstract Article PDF–689K

Select item 321442913.

Natamycin in the treatment of keratomycosis: Correlation of treatment outcome and in vitro susceptibility of fungal isolates

Linu Pradhan, Savitri Sharma, Suma Nalamada, Srikant K Sahu, Sujata Das, Prashant Garg

Indian J Ophthalmol. 2011 Nov-Dec; 59(6): 512–514. doi: 10.4103/0301-4738.86328

PMCID:: PMC3214429

Abstract Article PDF–395K

Select item 312275714.

Fungal Scleral Keratitis Caused by Phomopsis phoenicicola

Devarshi U. Gajjar, Anuradha K. Pal, Trilok J. Parmar, Anshul I. Arora, Darshini A. Ganatra, Forum B. Kayastha, Bharat K. Ghodadra, Abhay R. Vasavada

J Clin Microbiol. 2011 Jun; 49(6): 2365–2368. doi: 10.1128/JCM.02449-10

PMCID:: PMC3122757

Abstract Article PDF–1.0M

Select item 310029615.

Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome

Murthy Narayana Darisipudi, Ramanjaneyulu Allam, Khader Valli Rupanagudi, Hans-Joachim Anders

PLoS One. 2011; 6(5): e19588. Published online 2011 May 23. doi: 10.1371/journal.pone.0019588

PMCID:: PMC3100296

Abstract Article PDF–462K

Select item 305906316.

Molecular Control of Polyene Macrolide Biosynthesis: DIRECT BINDING OF THE REGULATOR PimM TO EIGHT PROMOTERS OF PIMARICIN GENES AND IDENTIFICATION OF BINDING BOXES

Javier Santos-Aberturas, Cláudia M. Vicente, Susana M. Guerra, Tamara D. Payero, Juan F. Martín, Jesús F. Aparicio

J Biol Chem. 2011 Mar 18; 286(11): 9150–9161. Published online 2010 Dec 27. doi: 10.1074/jbc.M110.182428

PMCID:: PMC3059063

Abstract Article PDF–3.2M

Select item 299291717.

Colletotrichum graminicola keratitis: First case report from India

Prakash P Yegneswaran, Vijaya Pai, Indira Bairy, Sulatha Bhandary

Indian J Ophthalmol. 2010 Sep-Oct; 58(5): 415–417. doi: 10.4103/0301-4738.67058

PMCID:: PMC2992917

Abstract Article PDF–1.6M

Select item 293265718.

Structure of cytochrome P450 PimD suggests epoxidation of the polyene macrolide pimaricin occurs via a hydroperoxoferric intermediate

Petrea M. Kells, Hugues Ouellet, Javier Santos-Aberturas, Jesus F. Aparicio, Larissa M. Podust

Chem Biol. Author manuscript; available in PMC 2011 Aug 27.

Published in final edited form as: Chem Biol. 2010 Aug 27; 17(8): 841–851. doi: 10.1016/j.chembiol.2010.05.026

PMCID:: PMC2932657

Abstract Article PDF–1.5M

Select item 287642719.

Natamycin Inhibits Vacuole Fusion at the Priming Phase via a Specific Interaction with Ergosterol

Yvonne Maria te Welscher, Lynden Jones, Martin Richard van Leeuwen, Jan Dijksterhuis, Ben de Kruijff, Gary Eitzen, Eefjan Breukink

Antimicrob Agents Chemother. 2010 Jun; 54(6): 2618–2625. Published online 2010 Apr 12. doi: 10.1128/AAC.01794-09

PMCID:: PMC2876427

Abstract Article PDF–738K

Select item 279852520.

In Vitro Activity of Thimerosal against Ocular Pathogenic Fungi

Yan Xu, Guangren Pang, Dongqing Zhao, Chuanwen Gao, Lutan Zhou, Shengtao Sun, Bingliang Wang

Antimicrob Agents Chemother. 2010 Jan; 54(1): 536–539. Published online 2009 Oct 19. doi: 10.1128/AAC.00714-09

PMCID:: PMC2798525

Abstract Article PDF–49K

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DB534761 RIKEN full-length enriched human cDNA library, hippocampus Homo sapiens...
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