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Select item 48047511.

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

Helena Dračínská, František Bárta, Kateřina Levová, Alena Hudecová, Michaela Moserová, Heinz H. Schmeiser, Klaus Kopka, Eva Frei, Volker M. Arlt, Marie Stiborová

Toxicology. 2016 Feb 17; 344-346: 7–18. doi: 10.1016/j.tox.2016.01.011

PMCID:: PMC4804751

Article PDF–1.8M

Select item 42586132.

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

Annette M. Krais, Karl-Rudolf Mühlbauer, Jill E. Kucab, Helena Chinbuah, Michael G. Cornelius, Quan-Xiang Wei, Monica Hollstein, David H. Phillips, Volker M. Arlt, Heinz H. Schmeiser

Toxicol In Vitro. 2015 Feb; 29(1): 34–43. doi: 10.1016/j.tiv.2014.09.004

PMCID:: PMC4258613

Article PDF–1.1M

Select item 42262393.

Detoxification of aristolochic acid I by O-demethylation: Less nephrotoxicity and genotoxicity of aristolochic acid la in rodents

Shinya Shibutani, Radha R. Bonala, Thomas Rosenquist, Robert Rieger, Naomi Suzuki, Francis Johnson, Frederick Miller, Arthur P. Grollman

Int J Cancer. Author manuscript; available in PMC 2014 Nov 10.

Published in final edited form as: Int J Cancer. 2010 Sep 1; 127(5): 1021–1027. doi: 10.1002/ijc.25141

PMCID:: PMC4226239

Article PDF–773K

Select item 40030154.

β-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism

Ying Xiao, Xiang Xue, Yuan-feng Wu, Guo-zheng Xin, Yong Qian, Tian-pei Xie, Li-kun Gong, Jin Ren

Acta Pharmacol Sin. 2009 Nov; 30(11): 1559–1565. Published online 2009 Nov 5. doi: 10.1038/aps.2009.156

PMCID:: PMC4003015

Article PDF–3.0M

Select item 40028425.

Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells

Ya-yin Chen, Su-yin Chiang, Hsiu-ching Wu, Shung-te Kao, Chien-yun Hsiang, Tin-yun Ho, Jaung-geng Lin

Acta Pharmacol Sin. 2010 Feb; 31(2): 227–236. Published online 2010 Feb 5. doi: 10.1038/aps.2009.197

PMCID:: PMC4002842

Article PDF–2.8M

Select item 39240916.

Increased Mortality Risk for Cancers of the Kidney
and Other Urinary Organs among Chinese Herbalists

Hsiao-Yu Yang, Jung-Der Wang, Tsai-Chang Lo, Pau-Chung Chen

J Epidemiol. 2009; 19(1): 17–23. Prepublished online 2009 Jan 22. Published online 2009 Jan 30. doi: 10.2188/jea.JE20080035

PMCID:: PMC3924091

Article PDF–101K

Select item 36213517.

Novel Assays for Detection of Urinary KIM-1 in Mouse Models of Kidney Injury

Venkata S. Sabbisetti, Kazumi Ito, Chang Wang, Li Yang, Stephen C. Mefferd, Joseph V. Bonventre

Toxicol Sci. 2013 Jan; 131(1): 13–25. Published online 2012 Sep 27. doi: 10.1093/toxsci/kfs268

PMCID:: PMC3621351

Article PDF–1.2M

Select item 35609128.

Aristolactam-DNA Adducts in the Renal Cortex: Biomarker of Environmental Exposure to Aristolochic Acid

Bojan Jelaković, Sandra Karanović, Ivana Vuković-Lela, Frederick Miller, Karen Edwards, Jovan Nikolić, Karla Tomić, Neda Slade, Branko Brdar, Robert Turesky, Želimir Stipanćić, Damir Dittrich, Arthur P. Grollman, Kathleen G. Dickman

Kidney Int. Author manuscript; available in PMC 2013 Jan 31.

Published in final edited form as: Kidney Int. 2012 Mar; 81(6): 559–567. Published online 2011 Nov 9. doi: 10.1038/ki.2011.371

PMCID:: PMC3560912

Article PDF–1.9M

Select item 35208779.

Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A₂ from Bothrops pirajai venom

Rafael M Ximenes, Renata S Alves, Ticiana P Pereira, Renata M Araújo, Edilberto R Silveira, Marcelo M Rabello, Marcelo Z Hernandes, Veronica C G Soares, Daniel Bristot, Camila L Pires, Daniela O Toyama, Henrique H Gaeta, Helena S A Monteiro, Marcos H Toyama

BMC Complement Altern Med. 2012; 12: 139. Published online 2012 Aug 27. doi: 10.1186/1472-6882-12-139

PMCID:: PMC3520877

Article PDF–1.6M

Select item 351960010.

The safety of Homnawakod herbal formula containing Aristolochia tagala Cham. in Wistar rats

Pinpat Tripatara, Winita Onlamul, Suksalin Booranasubkajorn, Jantanee Wattanarangsan, Sukit Huabprasert, Natchagorn Lumlerdkij, Pravit Akarasereenont, Tawee Laohapand

BMC Complement Altern Med. 2012; 12: 170. Published online 2012 Oct 3. doi: 10.1186/1472-6882-12-170

PMCID:: PMC3519600

Article PDF–983K

Select item 349505411.

Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN)

Stephen P Wooding, Srebrena Atanasova, Howard C Gunn, Rada Staneva, Invanka Dimova, Draga Toncheva

BMC Med Genet. 2012; 13: 96. Published online 2012 Oct 11. doi: 10.1186/1471-2350-13-96

PMCID:: PMC3495054

Article PDF–2.7M

Select item 338389512.

A fluorescence-based analysis of aristolochic acid-derived DNA adducts

Victor Romanov, Victoria Sidorenko, Thomas A. Rosenquist, Terry Whyard, Arthur P. Grollman

Anal Biochem. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Anal Biochem. 2012 Aug 1; 427(1): 49–51. Published online 2012 Apr 4. doi: 10.1016/j.ab.2012.03.027

PMCID:: PMC3383895

Article PDF–1.1M

Select item 336144913.

Aristolochic acid-associated urothelial cancer in Taiwan

Chung-Hsin Chen, Kathleen G. Dickman, Masaaki Moriya, Jiri Zavadil, Viktoriya S. Sidorenko, Karen L. Edwards, Dmitri V. Gnatenko, Lin Wu, Robert J. Turesky, Xue-Ru Wu, Yeong-Shiau Pu, Arthur P. Grollman

Proc Natl Acad Sci U S A. 2012 May 22; 109(21): 8241–8246. Published online 2012 Apr 9. doi: 10.1073/pnas.1119920109