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Links from Protein

Items: 6

1.
INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program
Francesca Pirini, Sebastian Rodriguez-Torres, Bola Grace Ayandibu, María Orera-Clemente, Alberto Gonzalez-De La Vega, Fahcina Lawson, Roland J. Thorpe Jr, David Sidransky, Rafael Guerrero-Preston
Mol Med Rep. 2018 Jan; 17(1): 1699–1709. Published online 2017 Nov 14. doi: 10.3892/mmr.2017.8039
PMCID:
PMC5780113
AbstractArticlePDF–1022K
2.
Hypoxia-inducible factor 1α activates insulin-induced gene 2 (Insig-2) transcription for degradation of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the liver
Seonghwan Hwang, Andrew D. Nguyen, Youngah Jo, Luke J. Engelking, James Brugarolas, Russell A. DeBose-Boyd
J Biol Chem. 2017 Jun 2; 292(22): 9382–9393. Published online 2017 Apr 17. doi: 10.1074/jbc.M117.788562
PMCID:
PMC5454117
AbstractArticlePDF–586K
3.
Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysines
Joon No Lee, Yi Gong, Xiangyu Zhang, Jin Ye
Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13): 4958–4963. Published online 2006 Mar 20. doi: 10.1073/pnas.0600422103
PMCID:
PMC1405624
AbstractArticlePDF–1.4M
4.
Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
Daisuke Yabe, Ryutaro Komuro, Guosheng Liang, Joseph L. Goldstein, Michael S. Brown
Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6): 3155–3160. Published online 2003 Mar 6. doi: 10.1073/pnas.0130116100
PMCID:
PMC152262
AbstractArticlePDF–256K
5.
Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols
Daisuke Yabe, Zong-Ping Xia, Christopher M. Adams, Robert B. Rawson
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16672–16677. Published online 2002 Dec 13. doi: 10.1073/pnas.262669399
PMCID:
PMC139202
AbstractArticlePDF–441K
6.
Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
Daisuke Yabe, Michael S. Brown, Joseph L. Goldstein
Proc Natl Acad Sci U S A. 2002 Oct 1; 99(20): 12753–12758. Published online 2002 Sep 19. doi: 10.1073/pnas.162488899
PMCID:
PMC130532
AbstractArticlePDF–296K

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