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Select item 56254811.

Positive and Negative Regulation of Type I Interferons by the Human T Cell Leukemia Virus Antisense Protein HBZ

Manraj Singh Narulla, Ahlam Alsairi, Lucie Charmier, Stephen Noonan, David Conroy, William W. Hall, Noreen Sheehy

J Virol. 2017 Oct 15; 91(20): e00853-17. Prepublished online 2017 Aug 2. Published online 2017 Sep 27. doi: 10.1128/JVI.00853-17

Correction in:: J Virol. 2018 Jan 15; 92(2): e01865-17.

PMCID:: PMC5625481

Abstract Article PDF–2.4M

Select item 41354662.

IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex

Alicia Y. Zhou, Rhine R. Shen, Eejung Kim, Ying J. Lock, Ming Xu, Zhijian J. Chen, William C. Hahn

Cell Rep. Author manuscript; available in PMC 2014 Aug 18.

Published in final edited form as: Cell Rep. 2013 Mar 28; 3(3): 724–733. Published online 2013 Feb 28. doi: 10.1016/j.celrep.2013.01.031

PMCID:: PMC4135466

Abstract Article PDF–1.4M

Select item 41140193.

Unanchored K48-linked poly-ubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase mediated antiviral response

Ricardo Rajsbaum, Gijs A. Versteeg, Sonja Schmid, Ana M. Maestre, Alan Belicha-Villanueva, Carles Martínez-Romero, Jenish R. Patel, Juliet Morrison, Giuseppe Pisanelli, Lisa Miorin, Maudry Laurent-Rolle, Hong M. Moulton, David A. Stein, Ana Fernandez-Sesma, Benjamin R. tenOever, Adolfo García-Sastre

Immunity. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Immunity. 2014 Jun 19; 40(6): 880–895. Published online 2014 May 29. doi: 10.1016/j.immuni.2014.04.018

PMCID:: PMC4114019

Abstract Article PDF–2.7M

Select item 36479724.

Human DEAD Box Helicase 3 Couples IκB Kinase ε to Interferon Regulatory Factor 3 Activation

Lili Gu, Anthony Fullam, Ruth Brennan, Martina Schröder

Mol Cell Biol. 2013 May; 33(10): 2004–2015. doi: 10.1128/MCB.01603-12

PMCID:: PMC3647972

Abstract Article PDF–3.2M

Select item 34216735.

Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-Activating Kinase IKKε

Christelle Pythoud, W. W. Shanaka I. Rodrigo, Giulia Pasqual, Sylvia Rothenberger, Luis Martínez-Sobrido, Juan Carlos de la Torre, Stefan Kunz

J Virol. 2012 Aug; 86(15): 7728–7738. doi: 10.1128/JVI.00187-12

PMCID:: PMC3421673

Abstract Article PDF–1.6M

Select item 30810216.

IκB kinase ε and TANK-binding kinase 1 activate AKT by direct phosphorylation

Xiaoduo Xie, Denghong Zhang, Bin Zhao, Min-Kan Lu, Ming You, Gianluigi Condorelli, Cun-Yu Wang, Kun-Liang Guan

Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16): 6474–6479. Published online 2011 Apr 4. doi: 10.1073/pnas.1016132108

PMCID:: PMC3081021

Abstract Article PDF–808K

Select item 29047777.

Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion

Haifeng Wang, Wang-Shick Ryu

PLoS Pathog. 2010 Jul; 6(7): e1000986. Published online 2010 Jul 15. doi: 10.1371/journal.ppat.1000986

PMCID:: PMC2904777

Abstract Article PDF–1022K

Select item 27127198.

Patterns of somatic mutation in human cancer genomes

Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L. Dalgliesh, Christopher Hunter, Graham Bignell, Helen Davies, Jon Teague, Adam Butler, Claire Stevens, Sarah Edkins, Sarah O'Meara, Imre Vastrik, Esther E. Schmidt, Tim Avis, Syd Barthorpe, Gurpreet Bhamra, Gemma Buck, Bhudipa Choudhury, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kris Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jon Hinton, Andy Jenkinson, David Jones, Andy Menzies, Tatiana Mironenko, Janet Perry, Keiran Raine, Dave Richardson, Rebecca Shepherd, Alexandra Small, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Sara Widaa, Andy Yates, Daniel P. Cahill, David N. Louis, Peter Goldstraw, Andrew G. Nicholson, Francis Brasseur, Leendert Looijenga, Barbara L. Weber, Yoke-Eng Chiew, Anna deFazio, Mel F. Greaves, Anthony R. Green, Peter Campbell, Ewan Birney, Douglas F. Easton, Georgia Chenevix-Trench, Min-Han Tan, Sok Kean Khoo, Bin Tean Teh, Siu Tsan Yuen, Suet Yi Leung, Richard Wooster, P. Andrew Futreal, Michael R. Stratton

Nature. Author manuscript; available in PMC 2009 Jul 20.

Published in final edited form as: Nature. 2007 Mar 8; 446(7132): 153–158. doi: 10.1038/nature05610

PMCID:: PMC2712719

Abstract Article PDF–867K

Select item 27091999.

Large-scale Proteomics Analysis of the Human Kinome

Felix S. Oppermann, Florian Gnad, Jesper V. Olsen, Renate Hornberger, Zoltán Greff, György Kéri, Matthias Mann, Henrik Daub

Mol Cell Proteomics. 2009 Jul; 8(7): 1751–1764. Published online 2009 Apr 15. doi: 10.1074/mcp.M800588-MCP200

PMCID:: PMC2709199

Abstract Article PDF–993K

Select item 265557910.

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKKɛ and TBK-1

Kathleen C. Prins, Washington B. Cárdenas, Christopher F. Basler

J Virol. 2009 Apr; 83(7): 3069–3077. Published online 2009 Jan 19. doi: 10.1128/JVI.01875-08

PMCID:: PMC2655579

Abstract Article PDF–685K

Select item 252935111.

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

Constantin S Friedman, Marie Anne O'Donnell, Diana Legarda-Addison, Aylwin Ng, Washington B Cárdenas, Jacob S Yount, Thomas M Moran, Christopher F Basler, Akihiko Komuro, Curt M Horvath, Ramnik Xavier, Adrian T Ting

EMBO Rep. 2008 Sep; 9(9): 930–936. Published online 2008 Jul 18. doi: 10.1038/embor.2008.136

PMCID:: PMC2529351

Abstract Article PDF–833K

Select item 251689012.

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

Martina Schröder, Marcin Baran, Andrew G Bowie

EMBO J. 2008 Aug 6; 27(15): 2147–2157. Published online 2008 Jul 17. doi: 10.1038/emboj.2008.143

PMCID:: PMC2516890

Abstract Article PDF–1.4M

Select item 245305913.

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

Didier Soulat, Tilmann Bürckstümmer, Sandra Westermayer, Adriana Goncalves, Angela Bauch, Adrijana Stefanovic, Oliver Hantschel, Keiryn L Bennett, Thomas Decker, Giulio Superti-Furga

EMBO J. 2008 Aug 6; 27(15): 2135–2146. Published online 2008 Jun 26. doi: 10.1038/emboj.2008.126

PMCID:: PMC2453059

Abstract Article PDF–484K

Select item 191409114.

SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK

Grigory Ryzhakov, Felix Randow

EMBO J. 2007 Jul 11; 26(13): 3180–3190. Published online 2007 Jun 14. doi: 10.1038/sj.emboj.7601743

PMCID:: PMC1914091

Abstract Article PDF–597K

Select item 191385215.

Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase

Feici Diao, Shu Li, Yang Tian, Min Zhang, Liang-Guo Xu, Yan Zhang, Rui-Peng Wang, Danying Chen, Zhonghe Zhai, Bo Zhong, Po Tien, Hong-Bing Shu

Proc Natl Acad Sci U S A. 2007 Jul 10; 104(28): 11706–11711. Published online 2007 Jun 28. doi: 10.1073/pnas.0700544104

PMCID:: PMC1913852

Abstract Article PDF–518K

Select item 135630416.

SIKE is an IKKɛ/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways

Jun Huang, Ting Liu, Liang-Guo Xu, Danying Chen, Zhonghe Zhai, Hong-Bing Shu

EMBO J. 2005 Dec 7; 24(23): 4018–4028. Published online 2005 Nov 10. doi: 10.1038/sj.emboj.7600863

PMCID:: PMC1356304

Abstract Article PDF–269K

Select item 52892817.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 20756318.

Identification of NAP1, a Regulatory Subunit of IκB Kinase-Related Kinases That Potentiates NF-κB Signaling

Fumitaka Fujita, Yuko Taniguchi, Takashi Kato, Yasuko Narita, Akiko Furuya, Tatsuhiro Ogawa, Hiroaki Sakurai, Takashi Joh, Makoto Itoh, Mireille Delhase, Michael Karin, Makoto Nakanishi

Mol Cell Biol. 2003 Nov; 23(21): 7780–7793. doi: 10.1128/MCB.23.21.7780-7793.2003

PMCID:: PMC207563

Abstract Article PDF–774K

Select item 647936019.

Structural and Computational Characterization of Disease-Related Mutations Involved in Protein-Protein Interfaces

Dàmaris Navío, Mireia Rosell, Josu Aguirre, Xavier de la Cruz, Juan Fernández-Recio

Int J Mol Sci. 2019 Apr; 20(7): 1583. Published online 2019 Mar 29. doi: 10.3390/ijms20071583

PMCID:: PMC6479360

Abstract Article PDF–1.7M

Select item 574290720.

New Targets for Zika Virus Determined by Human-Viral Interactomic: A Bioinformatics Approach

Eduardo Esteves, Nuno Rosa, Maria José Correia, Joel P. Arrais, Marlene Barros

Biomed Res Int. 2017; 2017: 1734151. Published online 2017 Dec 12. doi: 10.1155/2017/1734151

PMCID:: PMC5742907

Abstract Article PDF–1.6M

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