PMC Links for Protein (Select 14916485) - PMC - NCBI

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Items: 6

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 63228792.

Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis

Derek J. MacPherson, Caitlyn L. Mills, Mary Jo Ondrechen, Jeanne A. Hardy

J Biol Chem. 2019 Jan 4; 294(1): 71–88. Published online 2018 Nov 12. doi: 10.1074/jbc.RA118.005914

PMCID:: PMC6322879

Abstract Article PDF–5.6M

Select item 58593153.

Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency

Kevin B. Dagbay, Maureen E. Hill, Elizabeth Barrett, Jeanne A. Hardy

Biochemistry. Author manuscript; available in PMC 2018 Mar 20.

Published in final edited form as: Biochemistry. 2017 Aug 29; 56(34): 4568–4577. Published online 2017 Aug 16. doi: 10.1021/acs.biochem.7b00357

PMCID:: PMC5859315

Abstract Article PDF–750K

Select item 58496024.

Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity

Agne Tubeleviciute-Aydin, Libin Zhou, Gyanesh Sharma, Ishankumar V. Soni, Sergey N. Savinov, Jeanne A. Hardy, Andrea C. LeBlanc

Sci Rep. 2018; 8: 4428. Published online 2018 Mar 13. doi: 10.1038/s41598-018-22283-z

PMCID:: PMC5849602

Abstract Article PDF–4.2M

Select item 56172715.

Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions

Kevin B. Dagbay, Jeanne A. Hardy

Proc Natl Acad Sci U S A. 2017 Sep 19; 114(38): E7977–E7986. Published online 2017 Sep 1. doi: 10.1073/pnas.1704640114

PMCID:: PMC5617271

Abstract Article PDF–2.4M

Select item 386826.

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis.

A Takahashi, E S Alnemri, Y A Lazebnik, T Fernandes-Alnemri, G Litwack, R D Moir, R D Goldman, G G Poirier, S H Kaufmann, W C Earnshaw

Proc Natl Acad Sci U S A. 1996 Aug 6; 93(16): 8395–8400. doi: 10.1073/pnas.93.16.8395

PMCID:: PMC38682

Summary Page Browse PDF–1.6M

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PMC Links for Protein (Select 14916485) (6)
PMC
Homo sapiens caspase 6 (CASP6), RefSeqGene on chromosome 4; nuclear gene for mit...
Homo sapiens caspase 6 (CASP6), RefSeqGene on chromosome 4; nuclear gene for mitochondrial product
gi|2310188741|ref|NG_029187.2|

Nucleotide

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