PMC Links for Protein (Select 19923198) - PMC

Select item 67786451.

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Yasuo Kubota, Kumiko Uryu, Tatsuya Ito, Masafumi Seki, Tomoko Kawai, Tomoya Isobe, Tadayuki Kumagai, Tsutomu Toki, Kenichi Yoshida, Hiromichi Suzuki, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Kentaro Ohki, Nobutaka Kiyokawa, Jiro Kagawa, Satoru Miyano, Akira Oka, Yasuhide Hayashi, Seishi Ogawa, Kiminori Terui, Atsushi Sato, Kenichiro Hata, Etsuro Ito, Junko Takita

Cancer Sci. 2019 Oct; 110(10): 3358–3367. Published online 2019 Sep 10. doi: 10.1111/cas.14160

PMCID:: PMC6778645

Abstract Article PDF–2.1M

Select item 66702202.

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

Qingyuan Li, Qiuhua Lai, Chengcheng He, Yuxin Fang, Qun Yan, Yue Zhang, Xinke Wang, Chuncai Gu, Yiqing Wang, Liangying Ye, Lu Han, Xin Lin, Junsheng Chen, Jianqun Cai, Aimin Li, Side Liu

J Exp Clin Cancer Res. 2019; 38: 334. Published online 2019 Aug 1. doi: 10.1186/s13046-019-1330-9

PMCID:: PMC6670220

Abstract Article PDF–4.4M

Select item 65028103.

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

Navdeep Malik, Hualong Yan, Nellie Moshkovich, Murali Palangat, Howard Yang, Vanesa Sanchez, Zhuo Cai, Tyler J. Peat, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Beverly A. Mock, Stuart H. Yuspa, Daniel Larson, Lalage M. Wakefield, Jing Huang

Nat Commun. 2019; 10: 2071. Published online 2019 May 6. doi: 10.1038/s41467-019-10102-6

PMCID:: PMC6502810

Abstract Article PDF–3.1M

Select item 529424.

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

H Miyoshi, K Shimizu, T Kozu, N Maseki, Y Kaneko, M Ohki

Proc Natl Acad Sci U S A. 1991 Dec 1; 88(23): 10431–10434. doi: 10.1073/pnas.88.23.10431

PMCID:: PMC52942

Summary Page Browse PDF–965K

Select item 63296965.

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

Woori Jang, Joonhong Park, Ahlm Kwon, Hayoung Choi, Jiyeon Kim, Gun Dong Lee, Eunhee Han, Dong Wook Jekarl, Hyojin Chae, Kyungja Han, Jae-Ho Yoon, Seok Lee, Nack-Gyun Chung, Bin Cho, Myungshin Kim, Yonggoo Kim

Exp Mol Med. 2019 Jan; 51(1): 4. Published online 2019 Jan 11. doi: 10.1038/s12276-018-0195-x

PMCID:: PMC6329696

Abstract Article PDF–1.3M

Select item 59488136.

Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

Isaac KS Ng, Joanne Lee, Christopher Ng, Bustamin Kosmo, Lily Chiu, Elaine Seah, Michelle Meng Huang Mok, Karen Tan, Motomi Osato, Wee-Joo Chng, Benedict Yan, Lip Kun Tan

Biomark Res. 2018; 6: 16. Published online 2018 May 11. doi: 10.1186/s40364-018-0130-2

PMCID:: PMC5948813

Abstract Article PDF–677K

Select item 59081357.

RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia

Ioannis Panagopoulos, Ludmila Gorunova, Eva-Marie Jacobsen, Kristin Andersen, Francesca Micci, Sverre Heim

PLoS One. 2018; 13(4): e0196181. Published online 2018 Apr 19. doi: 10.1371/journal.pone.0196181

PMCID:: PMC5908135

Abstract Article PDF–2.7M

Select item 57705908.

Prevalence of somatic mutations in patients with aplastic anemia using peripheral blood cfDNA as compared with BM

A Albitar, D Townsley, W Ma, I De Dios, V Funari, N S Young, M Albitar

Leukemia. 2018 Jan; 32(1): 227–229. Prepublished online 2017 Aug 23. Published online 2017 Sep 15. doi: 10.1038/leu.2017.271

PMCID:: PMC5770590

Article PDF–425K

Select item 55465399.

Deregulation of the non-coding genome in leukemia

Susanna Teppo, Merja Heinäniemi, Olli Lohi

RNA Biol. 2017; 14(7): 827–830. Published online 2017 Apr 7. doi: 10.1080/15476286.2017.1312228

PMCID:: PMC5546539

Abstract Article PDF–521K

Select item 445795610.

Individualized Iterative Phenotyping for Genome-wide Analysis of Loss-of-Function Mutations

Jennifer J. Johnston, Katie L. Lewis, David Ng, Larry N. Singh, Jamila Wynter, Carmen Brewer, Brian P. Brooks, Isaac Brownell, Fabio Candotti, Steven G. Gonsalves, Suzanne P. Hart, Heidi H. Kong, Kristina I. Rother, Robert Sokolic, Benjamin D. Solomon, Wadih M. Zein, David N. Cooper, Peter D. Stenson, James C. Mullikin, Leslie G. Biesecker

Am J Hum Genet. 2015 Jun 4; 96(6): 913–925. doi: 10.1016/j.ajhg.2015.04.013

PMCID:: PMC4457956

Abstract Article PDF–219K

Select item 386403011.

Hereditary leukemia due to rare RUNX1c splice variant (L472X) presents with eczematous phenotype

A. Sorrell, C. Espenschied, W. Wang, J. Weitzel, S. Chu, P. Parker, S. Saldivar, R. Bhatia

Int J Clin Med. Author manuscript; available in PMC 2013 Dec 16.

Published in final edited form as: Int J Clin Med. 2012 Dec 1; 3(7): 10.4236/ijcm.2012.37110. Published online 2012 Dec 31. doi: 10.4236/ijcm.2012.37110

PMCID:: PMC3864030

Abstract Article PDF–699K

Select item 359009712.

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

Philipp A. Greif, Nikola P. Konstandin, Klaus H. Metzeler, Tobias Herold, Zlatana Pasalic, Bianka Ksienzyk, Annika Dufour, Friederike Schneider, Stephanie Schneider, Purvi M. Kakadia, Jan Braess, Maria Cristina Sauerland, Wolfgang E. Berdel, Thomas Büchner, Bernhard J. Woermann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander

Haematologica. 2012 Dec; 97(12): 1909–1915. doi: 10.3324/haematol.2012.064667

PMCID:: PMC3590097

Abstract Article PDF–2.0M

Select item 326757513.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L. Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch, Charles Lu, Shann-Ching Chen, Lei Wei, J. Racquel Collins-Underwood, Jing Ma, Kathryn G. Roberts, Stanley B. Pounds, Anatoly Ulyanov, Jared Becksfort, Pankaj Gupta, Robert Huether, Richard W. Kriwacki, Matthew Parker, Daniel J. McGoldrick, David Zhao, Daniel Alford, Stephen Espy, Kiran Chand Bobba, Guangchun Song, Deqing Pei, Cheng Cheng, Stefan Roberts, Michael I. Barbato, Dario Campana, Elaine Coustan-Smith, Sheila A. Shurtleff, Susana C. Raimondi, Maria Kleppe, Jan Cools, Kristin A. Shimano, Michelle L. Hermiston, Sergei Doulatov, Kolja Eppert, Elisa Laurenti, Faiyaz Notta, John E. Dick, Giuseppe Basso, Stephen P. Hunger, Mignon L. Loh, Meenakshi Devidas, Brent Wood, Stuart Winter, Kimberley P. Dunsmore, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, Christopher C. Harris, David J. Dooling, Kerri Ochoa, Kimberly J. Johnson, John C. Obenauer, William E. Evans, Ching-Hon Pui, Clayton W. Naeve, Timothy J. Ley, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Charles G. Mullighan

Nature. Author manuscript; available in PMC 2012 Jul 12.

Published in final edited form as: Nature. 2012 Jan 11; 481(7380): 157–163. Published online 2012 Jan 11. doi: 10.1038/nature10725

PMCID:: PMC3267575

Abstract Article PDF–1.9M

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