PMC Links for Protein (Select 203098753) - PMC

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 60487082.

Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer

Steven C. Eastlack, Shengli Dong, Cristina Ivan, Suresh K. Alahari

Mol Cancer. 2018; 17: 100. Published online 2018 Jul 16. doi: 10.1186/s12943-018-0851-8

PMCID:: PMC6048708

Abstract Article PDF–2.7M

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 43441214.

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

Rommel A. Mathias, Todd M. Greco, Adam Oberstein, Hanna G. Budayeva, Rumela Chakrabarti, Elizabeth A. Rowland, Yibin Kang, Thomas Shenk, Ileana M. Cristea

Cell. Author manuscript; available in PMC 2015 Dec 18.

Published in final edited form as: Cell. 2014 Dec 18; 159(7): 1615–1625. doi: 10.1016/j.cell.2014.11.046

PMCID:: PMC4344121

Abstract Article PDF–1.4M

Select item 2966465.

Defects in the E2 lipoyl transacetylase and the X-lipoyl containing component of the pyruvate dehydrogenase complex in patients with lactic acidemia.

B H Robinson, N MacKay, R Petrova-Benedict, I Ozalp, T Coskun, P W Stacpoole

J Clin Invest. 1990 Jun; 85(6): 1821–1824. doi: 10.1172/JCI114641

PMCID:: PMC296646

Summary Page Browse PDF–1.0M

Select item 41847756.

Phenylbutyrate increases pyruvate dehydrogenase complex activity in cells harboring a variety of defects

Rosa Ferriero, Audrey Boutron, Michele Brivet, Douglas Kerr, Eva Morava, Richard J Rodenburg, Luisa Bonafé, Matthias R Baumgartner, Yair Anikster, Nancy E Braverman, Nicola Brunetti-Pierri

Ann Clin Transl Neurol. 2014 Jul; 1(7): 462–470. Published online 2014 Jun 19. doi: 10.1002/acn3.73

PMCID:: PMC4184775

Abstract Article PDF–388K

Select item 41029247.

Phenylbutyrate Therapy for Pyruvate Dehydrogenase Complex Deficiency and Lactic Acidosis

Rosa Ferriero, Giuseppe Manco, Eleonora Lamantea, Edoardo Nusco, Mariella I. Ferrante, Paolo Sordino, Peter W. Stacpoole, Brendan Lee, Massimo Zeviani, Nicola Brunetti-Pierri

Sci Transl Med. Author manuscript; available in PMC 2014 Jul 18.

Published in final edited form as: Sci Transl Med. 2013 Mar 6; 5(175): 175ra31. doi: 10.1126/scitranslmed.3004986

PMCID:: PMC4102924

Abstract Article PDF–982K

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