PMC Links for Protein (Select 21735544) - PMC

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Items: 10

Select item 65571651.

Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells

Fiona Simpkins, Kibeom Jang, Hyunho Yoon, Karina E. Hew, Minsoon Kim, Diana J. Azzam, Jun Sun, Dekuang Zhao, Tan A. Ince, Wenbin Liu, Wei Guo, Zhi Wei, Gao Zhang, Gordon B. Mills, Joyce M. Slingerland

Clin Cancer Res. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Clin Cancer Res. 2018 Oct 1; 24(19): 4874–4886. Published online 2018 Jun 29. doi: 10.1158/1078-0432.CCR-17-3697

PMCID:: PMC6557165

Abstract Article PDF–918K

Select item 64824482.

Assessing Therapeutic Efficacy of MEK Inhibition in a KRAS^G12C-Driven Mouse Model of Lung Cancers

Shuai Li, Shengwu Liu, Jiehui Deng, Esra A. Akbay, Josephine Hai, Chiara Ambrogio, Long Zhang, Fangyu Zhou, Russell W. Jenkins, Dennis O. Adeegbe, Peng Gao, Xiaoen Wang, Cloud P. Paweletz, Grit S. Herter-Sprie, Ting Chen, Laura Gutiérrez-Quiceno, Yanxi Zhang, Ashley A. Merlino, Max M. Quinn, Yu Zeng, Xiaoting Yu, Yuting Liu, Lichao Fan, Andrew J. Aguirre, David A. Barbie, Xianghua Yi, Kwok-Kin Wong

Clin Cancer Res. Author manuscript; available in PMC 2019 Apr 25.

Published in final edited form as: Clin Cancer Res. 2018 Oct 1; 24(19): 4854–4864. Published online 2018 Jun 26. doi: 10.1158/1078-0432.CCR-17-3438

PMCID:: PMC6482448

Abstract Article PDF–1.5M

Select item 61251873.

MAPK reliance via acquired CDK4/6 inhibitor resistance in cancer

Renée de Leeuw, Christopher M. McNair, Matthew J. Schiewer, Neermala Poudel Neupane, Lucas J. Brand, Michael A. Augello, Zhen Li, Larry C. Cheng, Akihiro Yoshida, Sean M. Courtney, E. Starr Hazard, Gary Hardiman, Maha H. Hussain, J. Alan Diehl, Justin M. Drake, Wm. Kevin Kelly, Karen E. Knudsen

Clin Cancer Res. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Clin Cancer Res. 2018 Sep 1; 24(17): 4201–4214. Published online 2018 May 8. doi: 10.1158/1078-0432.CCR-18-0410

PMCID:: PMC6125187

Abstract Article PDF–1.2M

Select item 2325964.

Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.

Z Wu, J Wu, E Jacinto, M Karin

Mol Cell Biol. 1997 Dec; 17(12): 7407–7416. doi: 10.1128/mcb.17.12.7407

PMCID:: PMC232596

Summary PDF–1.2M

Select item 238225.

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH₂-terminal kinase

Cathy Tournier, Alan J. Whitmarsh, Julie Cavanagh, Tamera Barrett, Roger J. Davis

Proc Natl Acad Sci U S A. 1997 Jul 8; 94(14): 7337–7342. doi: 10.1073/pnas.94.14.7337

PMCID:: PMC23822

Abstract Article PDF–375K

Select item 45585156.

Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury

A Vercelli, S Biggi, A Sclip, I E Repetto, S Cimini, F Falleroni, S Tomasi, R Monti, N Tonna, F Morelli, V Grande, M Stravalaci, E Biasini, O Marin, F Bianco, D di Marino, T Borsello

Cell Death Dis. 2015 Aug; 6(8): e1854. Published online 2015 Aug 13. doi: 10.1038/cddis.2015.226

PMCID:: PMC4558515

Abstract Article PDF–3.3M

Select item 40385867.

Venus Kinase Receptors Control Reproduction in the Platyhelminth Parasite Schistosoma mansoni

Mathieu Vanderstraete, Nadège Gouignard, Katia Cailliau, Marion Morel, Steffen Hahnel, Silke Leutner, Svenja Beckmann, Christoph G. Grevelding, Colette Dissous

PLoS Pathog. 2014 May; 10(5): e1004138. Published online 2014 May 29. doi: 10.1371/journal.ppat.1004138