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Items: 1 to 20 of 32

1.
Structural mechanisms of inflammasome assembly
Alvin Lu, Hao Wu
FEBS J. Author manuscript; available in PMC 2019 Mar 5.
Published in final edited form as: FEBS J. 2015 Feb; 282(3): 435–444. Published online 2014 Nov 21. doi: 10.1111/febs.13133
PMCID:
PMC6400279
AbstractArticlePDF–1.3M
2.
NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy
Hiroshi Nakanishi, Yoshiyuki Kawashima, Kiyoto Kurima, Jae Jin Chae, Astin M. Ross, Gineth Pinto-Patarroyo, Seema K. Patel, Julie A. Muskett, Jessica S. Ratay, Parna Chattaraj, Yong Hwan Park, Sriharsha Grevich, Carmen C. Brewer, Michael Hoa, H. Jeffrey Kim, John A. Butman, Lori Broderick, Hal M. Hoffman, Ivona Aksentijevich, Daniel L. Kastner, Raphaela Goldbach-Mansky, Andrew J. Griffith
Proc Natl Acad Sci U S A. 2017 Sep 12; 114(37): E7766–E7775. Published online 2017 Aug 28. doi: 10.1073/pnas.1702946114
PMCID:
PMC5604003
AbstractArticlePDF–1.8M
3.
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
Tomonori Kimura, Ashish Jain, Seong Won Choi, Michael A. Mandell, Kate Schroder, Terje Johansen, Vojo Deretic
J Cell Biol. 2015 Sep 14; 210(6): 973–989. doi: 10.1083/jcb.201503023
PMCID:
PMC4576868
AbstractArticlePDF–3.1M
4.
De Novo CIAS1 Mutations, Cytokine Activation, and Evidence for Genetic Heterogeneity in Patients With Neonatal-Onset Multisystem Inflammatory Disease (NOMID): A New Member of the Expanding Family of Pyrin-Associated Autoinflammatory Diseases
Ivona Aksentijevich, Miroslawa Nowak, Mustapha Mallah, Jae Jin Chae, Wendy T. Watford, Sigrun R. Hofmann, Leonard Stein, Ricardo Russo, Donald Goldsmith, Peter Dent, Helene F. Rosenberg, Frances Austin, Elaine F. Remmers, James E. Balow, Jr., Sergio Rosenzweig, Hirsh Komarow, Nitza G. Shoham, Geryl Wood, Janet Jones, Nadira Mangra, Hector Carrero, Barbara S. Adams, Terry L. Moore, Kenneth Schikler, Hal Hoffman, Daniel J. Lovell, Robert Lipnick, Karyl Barron, John J O’Shea, Daniel L. Kastner, Raphaela Goldbach-Mansky
Arthritis Rheum. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Arthritis Rheum. 2002 Dec; 46(12): 3340–3348. doi: 10.1002/art.10688
PMCID:
PMC4556432
AbstractArticlePDF–1.0M
5.
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome
Hal M. Hoffman, James L. Mueller, David H. Broide, Alan A. Wanderer, Richard D. Kolodner
Nat Genet. Author manuscript; available in PMC 2015 Feb 9.
Published in final edited form as: Nat Genet. 2001 Nov; 29(3): 301–305. doi: 10.1038/ng756
PMCID:
PMC4322000
AbstractArticlePDF–1.5M
6.
Novel role of PKR in inflammasome activation and HMGB1 release
Ben Lu, Takahisa Nakamura, Karen Inouye, Jianhua Li, Yiting Tang, Peter Lundbäck, Sergio I Valdes-Ferrer, Peder S. Olofsson, Thomas Kalb, Jesse Roth, Yongrui Zou, Helena Erlandsson-Harris, Huan Yang, Jenny P-Y Ting, Haichao Wang, Ulf Andersson, Daniel J. Antoine, Sangeeta S. Chavan, Gökhan S. Hotamisligil, Kevin J. Tracey
Nature. Author manuscript; available in PMC 2014 Sep 15.
Published in final edited form as: Nature. 2012 Aug 30; 488(7413): 670–674. doi: 10.1038/nature11290
PMCID:
PMC4163918
AbstractArticlePDF–529K
7.
The PYRIN domain-only protein POP3 inhibits AIM2-like receptor inflammasomes and regulates responses to DNA virus infections
Sonal Khare, Rojo A. Ratsimandresy, Lúcia de Almeida, Carla M. Cuda, Stephanie L. Rellick, Alexander V. Misharin, Melissa C. Wallin, Anu Gangopadhyay, Eleonora Forte, Eva Gottwein, Harris Perlman, John C. Reed, David R. Greaves, Andrea Dorfleutner, Christian Stehlik
Nat Immunol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Nat Immunol. 2014 Apr; 15(4): 343–353. Published online 2014 Feb 16. doi: 10.1038/ni.2829
PMCID:
PMC4123781
AbstractArticlePDF–2.5M
8.
Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
Tony Jourdan, Grzegorz Godlewski, Resat Cinar, Adeline Bertola, Gergö Szanda, Jie Liu, Joseph Tarn, Tiffany Han, Bani Mukhopadhyay, Monica C Skarulis, Cynthia Ju, Myriam Aouadis, Michael P Czech, George Kunos
Nat Med. Author manuscript; available in PMC 2014 Jun 10.
Published in final edited form as: Nat Med. 2013 Sep; 19(9): 1132–1140. Published online 2013 Aug 18. doi: 10.1038/nm.3265
PMCID:
PMC4050982
AbstractArticlePDF–2.0M
9.
Unified Polymerization Mechanism for the Assembly of ASC-dependent Inflammasomes
Alvin Lu, VenkatGiri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K. Atianand, Matthijn Vos, Gunnar F. Schröder, Katherine A. Fitzgerald, Hao Wu, Edward H. Egelman
Cell. Author manuscript; available in PMC 2015 Mar 13.
Published in final edited form as: Cell. 2014 Mar 13; 156(6): 1193–1206. doi: 10.1016/j.cell.2014.02.008
PMCID:
PMC4000066
AbstractArticlePDF–4.9M
10.
The DEAH box RNA helicase DHX33 senses cytosolic RNA and activates the NLRP3 inflammasome
Hiroki Mitoma, Shino Hanabuchi, Taeil Kim, Musheng Bao, Zhiqiang Zhang, Naoshi Sugimoto, Yong-Jun Liu
Immunity. Author manuscript; available in PMC 2014 Jul 25.
Published in final edited form as: Immunity. 2013 Jul 25; 39(1): 123–135. Published online 2013 Jul 18. doi: 10.1016/j.immuni.2013.07.001
PMCID:
PMC3756931
AbstractArticlePDF–1.6M
11.
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin, Emad S. Alnemri
J Biol Chem. 2012 Oct 19; 287(43): 36617–36622. Published online 2012 Sep 4. doi: 10.1074/jbc.M112.407130
PMCID:
PMC3476327
AbstractArticlePDF–1.2M
12.
Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly
Ju Young Bae, Hyun Ho Park
J Biol Chem. 2011 Nov 11; 286(45): 39528–39536. Published online 2011 Aug 31. doi: 10.1074/jbc.M111.278812
PMCID:
PMC3234776
AbstractArticlePDF–2.7M
13.
Osteoblasts Express NLRP3, a Nucleotide-Binding Domain and Leucine-Rich Repeat Region Containing Receptor Implicated in Bacterially Induced Cell Death
Samuel H McCall, Mahnaz Sahraei, Amy B Young, Charles S Worley, Joseph A Duncan, Jenny Pan-Yun Ting, Ian Marriott
J Bone Miner Res. 2008 Jan; 23(1): 30–40. Published online 2007 Oct 1. doi: 10.1359/JBMR.071002
PMCID:
PMC2663588
AbstractArticlePDF–2.7M
14.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
15.
Chronic Infantile Neurological Cutaneous and Articular Syndrome Is Caused by Mutations in CIAS1, a Gene Highly Expressed in Polymorphonuclear Cells and Chondrocytes
Jérôme Feldmann, Anne-Marie Prieur, Pierre Quartier, Patrick Berquin, Stéphanie Certain, Elisabetta Cortis, Dominique Teillac-Hamel, Alain Fischer, Geneviève de Saint Basile
Am J Hum Genet. 2002 Jul; 71(1): 198–203. Published online 2002 May 24. doi: 10.1086/341357
Correction in:
Am J Hum Genet. 2002 Nov; 71(5): 1258.
PMCID:
PMC384980
AbstractArticlePDF–233K
16.
New Mutations of CIAS1 That Are Responsible for Muckle-Wells Syndrome and Familial Cold Urticaria: A Novel Mutation Underlies Both Syndromes
Catherine Dodé, Nathalie Le Dû, Laurence Cuisset, Frank Letourneur, Jean-Marie Berthelot, Gérard Vaudour, Alain Meyrier, Richard A Watts, David G. I. Scott, Anne Nicholls, Brigitte Granel, Camille Frances, François Garcier, Patrick Edery, Serge Boulinguez, Jean-Paul Domergues, Marc Delpech, Gilles Grateau
Am J Hum Genet. 2002 Jun; 70(6): 1498–1506. Published online 2002 Apr 25. doi: 10.1086/340786
PMCID:
PMC379138
AbstractArticlePDF–267K
17.
Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells
Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen
Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200
PMCID:
PMC310934
AbstractArticlePDF–1.3M
18.
Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks
Alexander J. Anderson, Thomas D. Jackson, David A. Stroud, Diana Stojanovski
Open Biol. 2019 Aug; 9(8): 190126. Published online 2019 Aug 7. doi: 10.1098/rsob.190126
PMCID:
PMC6731593
AbstractArticlePDF–913K
19.
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Rachael Barry, Sidonie Wicky John, Gianmaria Liccardi, Tencho Tenev, Isabel Jaco, Chih-Hong Chen, Justin Choi, Paulina Kasperkiewicz, Teresa Fernandes-Alnemri, Emad Alnemri, Marcin Drag, Yuan Chen, Pascal Meier
Nat Commun. 2018; 9: 3001. Published online 2018 Aug 1. doi: 10.1038/s41467-018-05321-2
PMCID:
PMC6070540
AbstractArticlePDF–4.0M
20.
Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration
Cassandra Kosmidou, Nikolaos E. Efstathiou, Mien V. Hoang, Shoji Notomi, Eleni K. Konstantinou, Masayuki Hirano, Kosuke Takahashi, Daniel E. Maidana, Pavlina Tsoka, Lucy Young, Evangelos S. Gragoudas, Timothy W. Olsen, Yuki Morizane, Joan W. Miller, Demetrios G. Vavvas
Sci Rep. 2018; 8: 461. Published online 2018 Jan 11. doi: 10.1038/s41598-017-17634-1
PMCID:
PMC5764999
AbstractArticlePDF–1.5M

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