PMC Links for Protein (Select 341604745) - PMC

Select item 66279831.

The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites

Manon Moulis, Elisa Grousset, Julien Faccini, Kevin Richetin, Gary Thomas, Cecile Vindis

Cells. 2019 Jun; 8(6): 638. Published online 2019 Jun 25. doi: 10.3390/cells8060638

PMCID:: PMC6627983

Abstract Article PDF–7.7M

Select item 63095002.

An insulin responsive sensor in the SIRT1 disordered region binds DBC1 and PACS-2 to control enzyme activity

Troy C. Krzysiak, Laurel Thomas, You-Jin Choi, Sylvain Auclair, Yiqi Qian, Shan Luan, Stephanie M. Krasnow, Laura L. Thomas, Leonardus M.I. Koharudin, Panayiotis V. Benos, Daniel L. Marks, Angela M. Gronenborn, Gary Thomas

Mol Cell. Author manuscript; available in PMC 2019 Dec 20.

Published in final edited form as: Mol Cell. 2018 Dec 20; 72(6): 985–998.e7. Published online 2018 Nov 8. doi: 10.1016/j.molcel.2018.10.007

PMCID:: PMC6309500

Abstract Article PDF–1.1M

Select item 59866943.

A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis

Heather E. Olson, Nolwenn Jean-Marçais, Edward Yang, Delphine Heron, Katrina Tatton-Brown, Paul A. van der Zwaag, Emilia K. Bijlsma, Bryan L. Krock, E. Backer, Erik-Jan Kamsteeg, Margje Sinnema, Margot R.F. Reijnders, David Bearden, Amber Begtrup, Aida Telegrafi, Roelineke J. Lunsing, Lydie Burglen, Gaetan Lesca, Megan T. Cho, Lacey A. Smith, Beth R. Sheidley, Christelle Moufawad El Achkar, Phillip L. Pearl, Annapurna Poduri, Cara M. Skraban, Jennifer Tarpinian, Addie I. Nesbitt, Dietje E. Fransen van de Putte, Claudia A.L. Ruivenkamp, Patrick Rump, Nicolas Chatron, Isabelle Sabatier, Julitta De Bellescize, Laurent Guibaud, David A. Sweetser, Jessica L. Waxler, Klaas J. Wierenga, DDD Study, Jean Donadieu, Vinodh Narayanan, Keri M. Ramsey, C4RCD Research Group, Caroline Nava, Jean-Baptiste Rivière, Antonio Vitobello, Frédéric Tran Mau-Them, Christophe Philippe, Ange-Line Bruel, Yannis Duffourd, Laurel Thomas, Stefan H. Lelieveld, Janneke Schuurs-Hoeijmakers, Han G. Brunner, Boris Keren, Julien Thevenon, Laurence Faivre, Gary Thomas, Christel Thauvin-Robinet

Am J Hum Genet. 2018 May 3; 102(5): 995–1007. Published online 2018 Apr 12. doi: 10.1016/j.ajhg.2018.03.005

Correction in:: Am J Hum Genet. 2018 Oct 4; 103(4): 631.

PMCID:: PMC5986694

Abstract Article PDF–1.2M

Select item 55910294.

Spatial Clustering of de Novo Missense Mutations Identifies Candidate Neurodevelopmental Disorder-Associated Genes

Stefan H. Lelieveld, Laurens Wiel, Hanka Venselaar, Rolph Pfundt, Gerrit Vriend, Joris A. Veltman, Han G. Brunner, Lisenka E.L.M. Vissers, Christian Gilissen

Am J Hum Genet. 2017 Sep 7; 101(3): 478–484. Published online 2017 Aug 31. doi: 10.1016/j.ajhg.2017.08.004

PMCID:: PMC5591029

Abstract Article PDF–785K

Select item 54829745.

Caught in the act – protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease

Gary Thomas, Joseph E. Aslan, Laurel Thomas, Pushkar Shinde, Ujwal Shinde, Thomas Simmen

J Cell Sci. 2017 Jun 1; 130(11): 1865–1876. doi: 10.1242/jcs.199463

PMCID:: PMC5482974

Abstract Article

Select item 27448586.

Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis

Joseph E. Aslan, Huihong You, Danielle M. Williamson, Jessica Endig, Robert T. Youker, Laurel Thomas, Hongjun Shu, Yuhong Du, Robert L. Milewski, Matthew H. Brush, Anthony Possemato, Kam Sprott, Haian Fu, Kenneth D. Greis, Douglas N. Runckel, Arndt Vogel, Gary Thomas

Mol Cell. Author manuscript; available in PMC 2010 May 14.

Published in final edited form as: Mol Cell. 2009 May 14; 34(4): 497–509. doi: 10.1016/j.molcel.2009.04.011

PMCID:: PMC2744858

Abstract Article PDF–3.4M

Select item 24416627.

The Subcellular Distribution of Calnexin Is Mediated by PACS-2

Nathan Myhill, Emily M. Lynes, Jalal A. Nanji, Anastassia D. Blagoveshchenskaya, Hao Fei, Katia Carmine Simmen, Timothy J. Cooper, Gary Thomas, Thomas Simmen

Mol Biol Cell. 2008 Jul; 19(7): 2777–2788. doi: 10.1091/mbc.E07-10-0995

PMCID:: PMC2441662

Abstract Article PDF–1.6M

Select item 24310578.

HIV-1 Nef Binds PACS-2 to Assemble a Multikinase Cascade That Triggers Major Histocompatibility Complex Class I (MHC-I) Down-regulation: ANALYSIS USING SHORT INTERFERING RNA AND KNOCK-OUT MICE

Katelyn M. Atkins, Laurel Thomas, Robert T. Youker, Melanie J. Harriff, Franco Pissani, Huihong You, Gary Thomas

J Biol Chem. 2008 Apr 25; 283(17): 11772–11784. doi: 10.1074/jbc.M707572200

PMCID:: PMC2431057

Abstract Article PDF–777K

Select item 5496249.

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

Michael Köttgen, Thomas Benzing, Thomas Simmen, Robert Tauber, Björn Buchholz, Sylvain Feliciangeli, Tobias B Huber, Bernhard Schermer, Albrecht Kramer-Zucker, Katja Höpker, Katia Carmine Simmen, Christoph Carl Tschucke, Richard Sandford, Emily Kim, Gary Thomas, Gerd Walz

EMBO J. 2005 Feb 23; 24(4): 705–716. Published online 2005 Feb 3. doi: 10.1038/sj.emboj.7600566

PMCID:: PMC549624

Abstract Article PDF–519K

Select item 54961910.

PACS-2 controls endoplasmic reticulum–mitochondria communication and Bid-mediated apoptosis

Thomas Simmen, Joseph E Aslan, Anastassia D Blagoveshchenskaya, Laurel Thomas, Lei Wan, Yang Xiang, Sylvain F Feliciangeli, Chien-Hui Hung, Colin M Crump, Gary Thomas

EMBO J. 2005 Feb 23; 24(4): 717–729. Published online 2005 Feb 3. doi: 10.1038/sj.emboj.7600559

Correction in:: EMBO J. 2005 Mar 23; 24(6): 1301.

PMCID:: PMC549619

Abstract Article PDF–763K

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