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Select item 62231291.

Cryo-EM structure of substrate-bound human telomerase holoenzyme

Thi Hoang Duong Nguyen, Jane Tam, Robert A. Wu, Basil J. Greber, Daniel Toso, Eva Nogales, Kathleen Collins

Nature. Author manuscript; available in PMC 2018 Nov 8.

Published in final edited form as: Nature. 2018 May; 557(7704): 190–195. Published online 2018 Apr 25. doi: 10.1038/s41586-018-0062-x

PMCID:: PMC6223129

Abstract Article PDF–5.0M

Select item 45144562.

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage

Ivo A. Hendriks, Louise W. Treffers, Matty Verlaan - de Vries, Jesper V. Olsen, Alfred C.O. Vertegaal

Cell Rep. Author manuscript; available in PMC 2016 Sep 10.

Published in final edited form as: Cell Rep. 2015 Mar 17; 10(10): 1778–1791. Published online 2015 Mar 12. doi: 10.1016/j.celrep.2015.02.033

PMCID:: PMC4514456

Abstract Article PDF–2.4M

Select item 44244103.

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

Zhenyu Xiao, Jer-Gung Chang, Ivo A. Hendriks, Jón Otti Sigurðsson, Jesper V. Olsen, Alfred C.O. Vertegaal

Mol Cell Proteomics. 2015 May; 14(5): 1419–1434. doi: 10.1074/mcp.O114.044792

PMCID:: PMC4424410

Abstract Article PDF–2.2M

Select item 42590104.

Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner

Ivo A. Hendriks, Rochelle C.J. D’Souza, Bing Yang, Matty Verlaan-de Vries, Matthias Mann, Alfred C.O. Vertegaal

Nat Struct Mol Biol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Nat Struct Mol Biol. 2014 Oct; 21(10): 927–936. Published online 2014 Sep 14. doi: 10.1038/nsmb.2890

PMCID:: PMC4259010

Abstract Article PDF–2.9M

Select item 41801185.

Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridylation of ncRNA and mRNA

Schraga Schwartz, Douglas A. Bernstein, Maxwell R. Mumbach, Marko Jovanovic, Rebecca H. Herbst, Brian X. León-Ricardo, Jesse M. Engreitz, Mitchell Guttman, Rahul Satija, Eric S. Lander, Gerald Fink, Aviv Regev

Cell. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Cell. 2014 Sep 25; 159(1): 148–162. Published online 2014 Sep 11. doi: 10.1016/j.cell.2014.08.028

PMCID:: PMC4180118

Abstract Article PDF–1.6M

Select item 41517166.

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

Francis Impens, Lilliana Radoshevich, Pascale Cossart, David Ribet

Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34): 12432–12437. Published online 2014 Aug 11. doi: 10.1073/pnas.1413825111

PMCID:: PMC4151716

Abstract Article PDF–1.0M

Select item 36807327.

HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Londoño-Vallejo, Matthias Mann, Frank Buchholz

EMBO J. 2013 Jun 12; 32(12): 1681–1701. Published online 2013 May 17. doi: 10.1038/emboj.2013.105

PMCID:: PMC3680732

Abstract Article PDF–1.6M

Select item 34339238.

Comparative Large Scale Characterization of Plant versus Mammal Proteins Reveals Similar and Idiosyncratic N-α-Acetylation Features

Willy V. Bienvenut, David Sumpton, Aude Martinez, Sergio Lilla, Christelle Espagne, Thierry Meinnel, Carmela Giglione

Mol Cell Proteomics. 2012 Jun; 11(6): M111.015131. Published online 2012 Jan 5. doi: 10.1074/mcp.M111.015131

PMCID:: PMC3433923

Abstract Article PDF–1.6M

Select item 32416509.

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme

Simon Lattmann, Michael B. Stadler, James P. Vaughn, Steven A. Akman, Yoshikuni Nagamine

Nucleic Acids Res. 2011 Nov; 39(21): 9390–9404. Published online 2011 Aug 16. doi: 10.1093/nar/gkr630

PMCID:: PMC3241650

Abstract Article PDF–2.8M

Select item 315580610.

Telomere shortening and loss of self-renewal in dyskeratosis congenita iPS cells

Luis F.Z. Batista, Matthew F. Pech, Franklin L. Zhong, Ha Nam Nguyen, Kathleen T. Xie, Arthur J. Zaug, Sharon M. Crary, Jinkuk Choi, Vittorio Sebastiano, Athena Cherry, Neelam Giri, Marius Wernig, Blanche P. Alter, Thomas R. Cech, Sharon A. Savage, Renee A. Reijo Pera, Steven E. Artandi

Nature. Author manuscript; available in PMC 2011 Dec 16.

Published in final edited form as: Nature. 2011 Jun 16; 474(7351): 399–402. Published online 2011 May 22. doi: 10.1038/nature10084

PMCID:: PMC3155806

Abstract Article PDF–1.1M

Select item 303957011.

Initial characterization of the human central proteome

Thomas R Burkard, Melanie Planyavsky, Ines Kaupe, Florian P Breitwieser, Tilmann Bürckstümmer, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge

BMC Syst Biol. 2011; 5: 17. Published online 2011 Jan 26. doi: 10.1186/1752-0509-5-17

PMCID:: PMC3039570

Abstract Article PDF–2.3M

Select item 287652112.

Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In Vivo

Emily D. Egan, Kathleen Collins

Mol Cell Biol. 2010 Jun; 30(11): 2775–2786. Published online 2010 Mar 29. doi: 10.1128/MCB.00151-10

PMCID:: PMC2876521

Abstract Article PDF–2.0M

Select item 277326913.

Pathogenic NAP57 mutations decrease ribonucleoprotein assembly in dyskeratosis congenita

Petar N. Grozdanov, Narcis Fernandez-Fuentes, Andras Fiser, U. Thomas Meier

Hum Mol Genet. 2009 Dec 1; 18(23): 4546–4551. Published online 2009 Sep 4. doi: 10.1093/hmg/ddp416

PMCID:: PMC2773269

Abstract Article PDF–287K

Select item 272807114.

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

Andrew S. Venteicher, Eladio B. Abreu, Zhaojing Meng, Kelly E. McCann, Rebecca M. Terns, Timothy D. Veenstra, Michael P. Terns, Steven E. Artandi

Science. Author manuscript; available in PMC 2009 Aug 17.

Published in final edited form as: Science. 2009 Jan 30; 323(5914): 644–648. doi: 10.1126/science.1165357

PMCID:: PMC2728071

Abstract Article PDF–2.9M

Select item 270919915.

Large-scale Proteomics Analysis of the Human Kinome

Felix S. Oppermann, Florian Gnad, Jesper V. Olsen, Renate Hornberger, Zoltán Greff, György Kéri, Matthias Mann, Henrik Daub

Mol Cell Proteomics. 2009 Jul; 8(7): 1751–1764. Published online 2009 Apr 15. doi: 10.1074/mcp.M800588-MCP200

PMCID:: PMC2709199

Abstract Article PDF–993K

Select item 268551816.

SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs

Petar N. Grozdanov, Sujayita Roy, Nupur Kittur, U. Thomas Meier

RNA. 2009 Jun; 15(6): 1188–1197. doi: 10.1261/rna.1532109

PMCID:: PMC2685518

Abstract Article PDF–773K

Select item 266528617.

The DNA sequence of the human X chromosome

Mark T. Ross, Darren V. Grafham, Alison J. Coffey, Steven Scherer, Kirsten McLay, Donna Muzny, Matthias Platzer, Gareth R. Howell, Christine Burrows, Christine P. Bird, Adam Frankish, Frances L. Lovell, Kevin L. Howe, Jennifer L. Ashurst, Robert S. Fulton, Ralf Sudbrak, Gaiping Wen, Matthew C. Jones, Matthew E. Hurles, T. Daniel Andrews, Carol E. Scott, Stephen Searle, Juliane Ramser, Adam Whittaker, Rebecca Deadman, Nigel P. Carter, Sarah E. Hunt, Rui Chen, Andrew Cree, Preethi Gunaratne, Paul Havlak, Anne Hodgson, Michael L. Metzker, Stephen Richards, Graham Scott, David Steffen, Erica Sodergren, David A. Wheeler, Kim C. Worley, Rachael Ainscough, Kerrie D. Ambrose, M. Ali Ansari-Lari, Swaroop Aradhya, Robert I. S. Ashwell, Anne K. Babbage, Claire L. Bagguley, Andrea Ballabio, Ruby Banerjee, Gary E. Barker, Karen F. Barlow, Ian P. Barrett, Karen N. Bates, David M. Beare, Helen Beasley, Oliver Beasley, Alfred Beck, Graeme Bethel, Karin Blechschmidt, Nicola Brady, Sarah Bray-Allen, Anne M. Bridgeman, Andrew J. Brown, Mary J. Brown, David Bonnin, Elspeth A. Bruford, Christian Buhay, Paula Burch, Deborah Burford, Joanne Burgess, Wayne Burrill, John Burton, Jackie M. Bye, Carol Carder, Laura Carrel, Joseph Chako, Joanne C. Chapman, Dean Chavez, Ellson Chen, Guan Chen, Yuan Chen, Zhijian Chen, Craig Chinault, Alfredo Ciccodicola, Sue Y. Clark, Graham Clarke, Chris M. Clee, Sheila Clegg, Kerstin Clerc-Blankenburg, Karen Clifford, Vicky Cobley, Charlotte G. Cole, Jen S. Conquer, Nicole Corby, Richard E. Connor, Robert David, Joy Davies, Clay Davis, John Davis, Oliver Delgado, Denise DeShazo, Pawandeep Dhami, Yan Ding, Huyen Dinh, Steve Dodsworth, Heather Draper, Shannon Dugan-Rocha, Andrew Dunham, Matthew Dunn, K. James Durbin, Ireena Dutta, Tamsin Eades, Matthew Ellwood, Alexandra Emery-Cohen, Helen Errington, Kathryn L. Evans, Louisa Faulkner, Fiona Francis, John Frankland, Audrey E. Fraser, Petra Galgoczy, James Gilbert, Rachel Gill, Gernot Glöckner, Simon G. Gregory, Susan Gribble, Coline Griffiths, Russell Grocock, Yanghong Gu, Rhian Gwilliam, Cerissa Hamilton, Elizabeth A. Hart, Alicia Hawes, Paul D. Heath, Katja Heitmann, Steffen Hennig, Judith Hernandez, Bernd Hinzmann, Sarah Ho, Michael Hoffs, Phillip J. Howden, Elizabeth J. Huckle, Jennifer Hume, Paul J. Hunt, Adrienne R. Hunt, Judith Isherwood, Leni Jacob, David Johnson, Sally Jones, Pieter J. de Jong, Shirin S. Joseph, Stephen Keenan, Susan Kelly, Joanne K. Kershaw, Ziad Khan, Petra Kioschis, Sven Klages, Andrew J. Knights, Anna Kosiura, Christie Kovar-Smith, Gavin K. Laird, Cordelia Langford, Stephanie Lawlor, Margaret Leversha, Lora Lewis, Wen Liu, Christine Lloyd, David M. Lloyd, Hermela Loulseged, Jane E. Loveland, Jamieson D. Lovell, Ryan Lozado, Jing Lu, Rachael Lyne, Jie Ma, Manjula Maheshwari, Lucy H. Matthews, Jennifer McDowall, Stuart McLaren, Amanda McMurray, Patrick Meidl, Thomas Meitinger, Sarah Milne, George Miner, Shailesh L. Mistry, Margaret Morgan, Sidney Morris, Ines Müller, James C. Mullikin, Ngoc Nguyen, Gabriele Nordsiek, Gerald Nyakatura, Christopher N. O’Dell, Geoffery Okwuonu, Sophie Palmer, Richard Pandian, David Parker, Julia Parrish, Shiran Pasternak, Dina Patel, Alex V. Pearce, Danita M. Pearson, Sarah E. Pelan, Lesette Perez, Keith M. Porter, Yvonne Ramsey, Kathrin Reichwald, Susan Rhodes, Kerry A. Ridler, David Schlessinger, Mary G. Schueler, Harminder K. Sehra, Charles Shaw-Smith, Hua Shen, Elizabeth M. Sheridan, Ratna Shownkeen, Carl D. Skuce, Michelle L. Smith, Elizabeth C. Sotheran, Helen E. Steingruber, Charles A. Steward, Roy Storey, R. Mark Swann, David Swarbreck, Paul E. Tabor, Stefan Taudien, Tineace Taylor, Brian Teague, Karen Thomas, Andrea Thorpe, Kirsten Timms, Alan Tracey, Steve Trevanion, Anthony C. Tromans, Michele d’Urso, Daniel Verduzco, Donna Villasana, Lenee Waldron, Melanie Wall, Qiaoyan Wang, James Warren, Georgina L. Warry, Xuehong Wei, Anthony West, Siobhan L. Whitehead, Mathew N. Whiteley, Jane E. Wilkinson, David L. Willey, Gabrielle Williams, Leanne Williams, Angela Williamson, Helen Williamson, Laurens Wilming, Rebecca L. Woodmansey, Paul W. Wray, Jennifer Yen, Jingkun Zhang, Jianling Zhou, Huda Zoghbi, Sara Zorilla, David Buck, Richard Reinhardt, Annemarie Poustka, André Rosenthal, Hans Lehrach, Alfons Meindl, Patrick J. Minx, LaDeana W. Hillier, Huntington F. Willard, Richard K. Wilson, Robert H. Waterston, Catherine M. Rice, Mark Vaudin, Alan Coulson, David L. Nelson, George Weinstock, John E. Sulston, Richard Durbin, Tim Hubbard, Richard A. Gibbs, Stephan Beck, Jane Rogers, David R. Bentley

Nature. Author manuscript; available in PMC 2009 Apr 5.

Published in final edited form as: Nature. 2005 Mar 17; 434(7031): 325–337. doi: 10.1038/nature03440

PMCID:: PMC2665286

Abstract Article PDF–1.0M

Select item 250483518.

A quantitative atlas of mitotic phosphorylation

Noah Dephoure, Chunshui Zhou, Judit Villén, Sean A. Beausoleil, Corey E. Bakalarski, Stephen J. Elledge, Steven P. Gygi

Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31): 10762–10767. Published online 2008 Jul 31. doi: 10.1073/pnas.0805139105

PMCID:: PMC2504835

Abstract Article PDF–1.0M

Select item 206381219.

Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells

Xavier Darzacq, Nupur Kittur, Sujayita Roy, Yaron Shav-Tal, Robert H. Singer, U. Thomas Meier

J Cell Biol. 2006 Apr 24; 173(2): 207–218. doi: 10.1083/jcb.200601105

PMCID:: PMC2063812

Abstract Article PDF–4.0M

Select item 144090120.

hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase

Coralie Hoareau-Aveilla, Mattia Bonoli, Michele Caizergues-Ferrer, Yves Henry

RNA. 2006 May; 12(5): 832–840. doi: 10.1261/rna.2344106

PMCID:: PMC1440901

Abstract Article PDF–752K

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