PMC Links for Protein (Select 4758356) - PMC

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Items: 10

Select item 68923931.

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2019 Dec 4.

Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008

PMCID:: PMC6892393

Abstract Article PDF–1.7M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 62654643.

Structural basis of 5′ flap recognition and protein–protein interactions of human flap endonuclease 1

Hong Xu, Rongyi Shi, Wanchun Han, Jiahui Cheng, Xiaoli Xu, Kaiying Cheng, Liangyan Wang, Bing Tian, Li Zheng, Binghui Shen, Yuejin Hua, Ye Zhao

Nucleic Acids Res. 2018 Nov 30; 46(21): 11315–11325. Published online 2018 Oct 8. doi: 10.1093/nar/gky911

PMCID:: PMC6265464

Abstract Article PDF–7.0M

Select item 62315314.

SUMO-1 modification of FEN1 facilitates its interaction with Rad9–Rad1–Hus1 to counteract DNA replication stress

Xiaoli Xu, Rongyi Shi, Li Zheng, Zhigang Guo, Liangyan Wang, Mian Zhou, Ye Zhao, Bing Tian, Khue Truong, Yuan Chen, Binghui Shen, Yuejin Hua, Hong Xu

J Mol Cell Biol. 2018 Oct; 10(5): 460–474. Published online 2018 Oct 15. doi: 10.1093/jmcb/mjy047

PMCID:: PMC6231531

Abstract Article PDF–2.3M

Select item 61600675.

rs4246215 is targeted by hsa-miR1236 to regulate FEN1 expression but is not associated with Fuchs’ endothelial corneal dystrophy

Gargi Gouranga Nanda, Malloji Vinay Kumar, Laxmipriya Pradhan, Biswajit Padhy, Satabdi Sundaray, Sujata Das, Debasmita Pankaj Alone

PLoS One. 2018; 13(9): e0204278. Published online 2018 Sep 27. doi: 10.1371/journal.pone.0204278

PMCID:: PMC6160067

Abstract Article PDF–3.6M

Select item 3588606.

Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.

J M Murray, M Tavassoli, R al-Harithy, K S Sheldrick, A R Lehmann, A M Carr, F Z Watts

Mol Cell Biol. 1994 Jul; 14(7): 4878–4888. doi: 10.1128/mcb.14.7.4878

PMCID:: PMC358860

Summary Page Browse PDF–2.3M

Select item 39569757.

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells

Yinghao Zhang, Fang-Mei Chang, Jianjun Huang, Jacob J. Junco, Shivani K. Maffi, Hannah I. Pridgen, Gabriel Catano, Hong Dang, Xiang Ding, Fuquan Yang, Dae Joon Kim, Thomas J. Slaga, Rongqiao He, Sung-Jen Wei

Protein Cell. 2014 Feb; 5(2): 124–140. Published online 2014 Feb 11. doi: 10.1007/s13238-013-0018-8