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Links from Protein

Items: 1 to 20 of 39

1.
MEK drives BRAF activation through allosteric control of KSR proteins
Hugo Lavoie, Malha Sahmi, Pierre Maisonneuve, Sara A. Marullo, Neroshan Thevakumaran, Ting Jin, Igor Kurinov, Frank Sicheri, Marc Therrien
Nature. Author manuscript; available in PMC 2019 Mar 25.
Published in final edited form as: Nature. 2018 Feb 22; 554(7693): 549–553. Published online 2018 Feb 12. doi: 10.1038/nature25478
PMCID:
PMC6433120
AbstractArticlePDF–2.4M
2.
Molecular and functional analysis of a novel MEK2 mutation in cardio-facio-cutaneous syndrome: Transmission through four generations
Katherine A. Rauen, William E. Tidyman, Anne L. Estep, Srirangan Sampath, Henry M. Peltier, Sherri J. Bale, Yves Lacassie
Am J Med Genet A. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Am J Med Genet A. 2010 Apr; 0(4): 807–814. doi: 10.1002/ajmg.a.33342
PMCID:
PMC4180666
AbstractArticlePDF–633K
3.
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
K. Thangavelu, Catherine Qiurong Pan, Tobias Karlberg, Ganapathy Balaji, Mahesh Uttamchandani, Valiyaveettil Suresh, Herwig Schüler, Boon Chuan Low, J. Sivaraman
Proc Natl Acad Sci U S A. 2012 May 15; 109(20): 7705–7710. Published online 2012 Apr 26. doi: 10.1073/pnas.1116573109
PMCID:
PMC3356676
AbstractArticlePDF–993K
4.
Initial characterization of the human central proteome
Thomas R Burkard, Melanie Planyavsky, Ines Kaupe, Florian P Breitwieser, Tilmann Bürckstümmer, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge
BMC Syst Biol. 2011; 5: 17. Published online 2011 Jan 26. doi: 10.1186/1752-0509-5-17
PMCID:
PMC3039570
AbstractArticlePDF–2.3M
5.
Large-scale Proteomics Analysis of the Human Kinome
Felix S. Oppermann, Florian Gnad, Jesper V. Olsen, Renate Hornberger, Zoltán Greff, György Kéri, Matthias Mann, Henrik Daub
Mol Cell Proteomics. 2009 Jul; 8(7): 1751–1764. Published online 2009 Apr 15. doi: 10.1074/mcp.M800588-MCP200
PMCID:
PMC2709199
AbstractArticlePDF–993K
6.
A quantitative atlas of mitotic phosphorylation
Noah Dephoure, Chunshui Zhou, Judit Villén, Sean A. Beausoleil, Corey E. Bakalarski, Stephen J. Elledge, Steven P. Gygi
Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31): 10762–10767. Published online 2008 Jul 31. doi: 10.1073/pnas.0805139105
PMCID:
PMC2504835
AbstractArticlePDF–1.0M
7.
Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling
Rohit Mittal, Sew-Yeu Peak-Chew, Harvey T. McMahon
Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18574–18579. Published online 2006 Nov 20. doi: 10.1073/pnas.0608995103
PMCID:
PMC1654131
AbstractArticlePDF–1.3M
8.
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor.
G Vitale, L Bernardi, G Napolitani, M Mock, C Montecucco
Biochem J. 2000 Dec 15; 352(Pt 3): 739–745.
PMCID:
PMC1221512
SummaryPDF–243K
9.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
10.
Kinase Suppressor of Ras Forms a Multiprotein Signaling Complex and Modulates MEK Localization
Scott Stewart, Meera Sundaram, Yanping Zhang, Jeeyong Lee, Min Han, Kun-Liang Guan
Mol Cell Biol. 1999 Aug; 19(8): 5523–5534. doi: 10.1128/mcb.19.8.5523
PMCID:
PMC84397
AbstractArticlePDF–1.0M
11.
Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer
Man Hu, Zhaomin Yu, Peiyuan Mei, Jinxiao Li, Dan Luo, Haiming Zhang, Minfeng Zhou, Fengxia Liang, Rui Chen
Aging (Albany NY) 2020 Jan 15; 12(1): 138–155. Published online 2020 Jan 3. doi: 10.18632/aging.102606
Correction in:
Aging (Albany NY). 2020 Apr 15; 12(7): 6488–6489.
PMCID:
PMC6977686
AbstractArticlePDF–5.4M
12.
The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data
Marina Wright Muelas, Farah Mughal, Steve O’Hagan, Philip J. Day, Douglas B. Kell
Sci Rep. 2019; 9: 17960. Published online 2019 Nov 29. doi: 10.1038/s41598-019-54288-7
PMCID:
PMC6884504
AbstractArticlePDF–5.9M
13.
A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins
Giuseppe Rigogliuso, Martin L. Biniossek, John L. Goodier, Bettina Mayer, Gavin C. Pereira, Oliver Schilling, Eckart Meese, Jens Mayer
Mob DNA. 2019; 10: 36. Published online 2019 Aug 22. doi: 10.1186/s13100-019-0178-z
PMCID:
PMC6707001
AbstractArticlePDF–5.3M
14.
Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and deregulation of RNA metabolism
Jemma Dunn, Sara Ferluga, Vikram Sharma, Matthias Futschik, David A. Hilton, Claire L. Adams, Edwin Lasonder, C. Oliver Hanemann
EBioMedicine. 2019 Feb; 40: 77–91. Published online 2018 Dec 26. doi: 10.1016/j.ebiom.2018.12.048
PMCID:
PMC6412084
AbstractArticlePDF–4.4M
15.
Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes
Trevor Pentzien, Bhanwar L. Puniya, Tomáš Helikar, Mihaela T. Matache
Front Physiol. 2018; 9: 1185. Published online 2018 Aug 31. doi: 10.3389/fphys.2018.01185
PMCID:
PMC6127445
AbstractArticlePDF–4.9M
16.
Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis
Gloria Barbarani, Antonella Ronchi, Margherita Ruoppolo, Lucia Santorelli, Robert Steinfelder, Sudharshan Elangovan, Cristina Fugazza, Marianna Caterino
Sci Rep. 2017; 7: 14088. Published online 2017 Oct 26. doi: 10.1038/s41598-017-14336-6
PMCID:
PMC5658338
AbstractArticlePDF–4.4M
17.
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes
Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Neil V Marrion, John A Peters, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators
Br J Pharmacol. 2017 Dec; 174(Suppl Suppl 1): S272–S359. Published online 2017 Oct 21. doi: 10.1111/bph.13877
PMCID:
PMC5650666
AbstractArticlePDF–1.8M
18.
p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation
Ding'an Zhou, Zhongshu Kuang, Xing Zeng, Ke Wang, Jiangshu Ma, Huangchao Luo, Mei Chen, Yan Li, Jiawei Zeng, Shu Li, Fujun Luan, Yong He, Hongying Dai, Beizhong Liu, Hui Li, Lin He, Qinghe Xing
J Cell Mol Med. 2017 Oct; 21(10): 2465–2480. Published online 2017 Apr 6. doi: 10.1111/jcmm.13168
PMCID:
PMC5618682
AbstractArticlePDF–5.5M
19.
Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis
Kaitlyn Schaaf, Samuel R. Smith, Alexandra Duverger, Frederic Wagner, Frank Wolschendorf, Andrew O. Westfall, Olaf Kutsch, Jim Sun
Sci Rep. 2017; 7: 42101. Published online 2017 Feb 8. doi: 10.1038/srep42101
PMCID:
PMC5296758
AbstractArticlePDF–1.8M
20.
A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia
Aurore Perrot, Cédric Pionneau, Sophie Nadaud, Frédéric Davi, Véronique Leblond, Frédéric Jacob, Hélène Merle-Béral, Raoul Herbrecht, Marie-Christine Béné, John G. Gribben, Seiamak Bahram, Laurent Vallat
Blood. 2011 Jul 28; 118(4): e1–e15. Prepublished online 2011 May 20. doi: 10.1182/blood-2011-02-335125
PMCID:
PMC5292594
AbstractArticle

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