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Items: 1 to 20 of 30

1.
Evolutionary Trajectories for the Functional Diversification of Anthracycline Methyltransferases
Thadée Grocholski, Keith Yamada, Jari Sinkkonen, Heli Tirkkonen, Jarmo Niemi, Mikko Metsä-Ketelä
ACS Chem Biol. 2019 May 17; 14(5): 850–856. Published online 2019 Apr 17. doi: 10.1021/acschembio.9b00238
PMCID:
PMC6750894
AbstractArticlePDF–2.2M
2.
Monooxygenation of aromatic compounds by flavin‐dependent monooxygenases
Pirom Chenprakhon, Thanyaporn Wongnate, Pimchai Chaiyen
Protein Sci. 2019 Jan; 28(1): 8–29. Published online 2018 Dec 17. doi: 10.1002/pro.3525
PMCID:
PMC6295904
AbstractArticlePDF–2.6M
3.
Microbial Extracellular Polymeric Substances: Ecological Function and Impact on Soil Aggregation
Ohana Y. A. Costa, Jos M. Raaijmakers, Eiko E. Kuramae
Front Microbiol. 2018; 9: 1636. Published online 2018 Jul 23. doi: 10.3389/fmicb.2018.01636
PMCID:
PMC6064872
AbstractArticlePDF–1.7M
4.
Confronting the catalytic dark matter encoded by sequenced genomes
Kenneth W. Ellens, Nils Christian, Charandeep Singh, Venkata P. Satagopam, Patrick May, Carole L. Linster
Nucleic Acids Res. 2017 Nov 16; 45(20): 11495–11514. Published online 2017 Oct 20. doi: 10.1093/nar/gkx937
PMCID:
PMC5714238
AbstractArticlePDF–2.8M
5.
The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase
Li-Kai Liu, Heba Abdelwahab, Julia S. Martin Del Campo, Ritcha Mehra-Chaudhary, Pablo Sobrado, John J. Tanner
J Biol Chem. 2016 Oct 7; 291(41): 21553–21562. Published online 2016 Aug 24. doi: 10.1074/jbc.M116.745315
PMCID:
PMC5076826
AbstractArticlePDF–2.4M
6.
NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I
Virginie F. Rhein, Joe Carroll, Shujing Ding, Ian M. Fearnley, John E. Walker
J Biol Chem. 2016 Jul 8; 291(28): 14851–14860. Published online 2016 May 18. doi: 10.1074/jbc.M116.734970
PMCID:
PMC4938201
AbstractArticlePDF–2.7M
7.
Divergent evolution of an atypical S-adenosyl-l-methionine–dependent monooxygenase involved in anthracycline biosynthesis
Thadée Grocholski, Pedro Dinis, Laila Niiranen, Jarmo Niemi, Mikko Metsä-Ketelä
Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32): 9866–9871. Published online 2015 Jul 27. doi: 10.1073/pnas.1501765112
PMCID:
PMC4538628
AbstractArticlePDF–1.2M
8.
Structures of the Apo and FAD-Bound Forms of 2-Hydroxybiphenyl 3-monooxygenase (HbpA) Locate Activity Hotspots Identified by Using Directed Evolution
Chantel N Jensen, Tamara Mielke, Joseph E Farrugia, Annika Frank, Henry Man, Sam Hart, Johan P Turkenburg, Gideon Grogan
Chembiochem. 2015 Apr 13; 16(6): 968–976. Published online 2015 Mar 3. doi: 10.1002/cbic.201402701
PMCID:
PMC4515095
AbstractArticlePDF–1.6M
9.
Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin
Heather A. Cooke, Elizabeth L. Guenther, Yinggang Luo, Ben Shen, Steven D. Bruner
Biochemistry. Author manuscript; available in PMC 2015 Jul 13.
Published in final edited form as: Biochemistry. 2009 Oct 13; 48(40): 9590–9598. doi: 10.1021/bi901257q
PMCID:
PMC4500170
AbstractArticlePDF–1.3M
10.
Structural Insights into the Catalytic Mechanism of Synechocystis Magnesium Protoporphyrin IX O-Methyltransferase (ChlM)
Xuemin Chen, Xiao Wang, Juan Feng, Yuhong Chen, Ying Fang, Shun Zhao, Aiguo Zhao, Min Zhang, Lin Liu
J Biol Chem. 2014 Sep 12; 289(37): 25690–25698. Published online 2014 Jul 30. doi: 10.1074/jbc.M114.584920
PMCID:
PMC4162172
AbstractArticlePDF–3.0M
11.
Natural products for cancer chemotherapy
Arnold L. Demain, Preeti Vaishnav
Microb Biotechnol. 2011 Nov; 4(6): 687–699. Published online 2011 Oct 14. doi: 10.1111/j.1751-7915.2010.00221.x
PMCID:
PMC3815406
AbstractArticlePDF–808K
12.
Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli
Barry Scott, Carolyn A. Young, Sanjay Saikia, Lisa K. McMillan, Brendon J. Monahan, Albert Koulman, Jonathan Astin, Carla J. Eaton, Andrea Bryant, Ruth E. Wrenn, Sarah C. Finch, Brian A. Tapper, Emily J. Parker, Geoffrey B. Jameson
Toxins (Basel) 2013 Aug; 5(8): 1422–1446. Published online 2013 Aug 14. doi: 10.3390/toxins5081422
PMCID:
PMC3760044
AbstractArticlePDF–4.2M
13.
Rhodomycin analogues from Streptomyces purpurascens: isolation, characterization and biological activities
Sunita Holkar, Deovrat Begde, Nandita Nashikkar, Tukaram Kadam, Avinash Upadhyay
Springerplus. 2013; 2: 93. Published online 2013 Mar 9. doi: 10.1186/2193-1801-2-93
PMCID:
PMC3667366
AbstractArticlePDF–1.3M
14.
A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea
Qing Peng, Xue Zhang, Meng Shang, Xu Wang, Guili Wang, Bingxue Li, Guohua Guan, Ying Li, Youshao Wang
Microb Cell Fact. 2011; 10: 95. Published online 2011 Nov 9. doi: 10.1186/1475-2859-10-95
PMCID:
PMC3226443
AbstractArticlePDF–574K
15.
Recombinant organisms for production of industrial products
Jose-Luis Adrio, Arnold L Demain
Bioeng Bugs. 2010 Mar-Apr; 1(2): 116–131. Published online 2009 Nov 2. doi: 10.4161/bbug.1.2.10484
PMCID:
PMC3026452
AbstractArticlePDF–1.5M
16.
In Vivo Investigation of the Roles of FdmM and FdmM1 in Fredericamycin Biosynthesis Unveiling a New Family of Oxygenases
Yihua Chen, Evelyn Wendt-Pienkoski, Scott R. Rajski, Ben Shen
J Biol Chem. 2009 Sep 11; 284(37): 24735–24743. Published online 2009 Jul 20. doi: 10.1074/jbc.M109.014191
PMCID:
PMC2757177
AbstractArticlePDF–1.0M
17.
In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites
Mohd Zeeshan Ansari, Jyoti Sharma, Rajesh S Gokhale, Debasisa Mohanty
BMC Bioinformatics. 2008; 9: 454. Published online 2008 Oct 25. doi: 10.1186/1471-2105-9-454
PMCID:
PMC2613160
AbstractArticlePDF–4.7M
18.
Structural and Functional Analysis of the Pyocyanin Biosynthetic Protein PhzM from Pseudomonas aeruginosa
James F. Parsons, Bryan T. Greenhagen, Katherine Shi, Kelly Calabrese, Howard Robinson, Jane E. Ladner
Biochemistry. Author manuscript; available in PMC 2008 Oct 23.
Published in final edited form as: Biochemistry. 2007 Feb 20; 46(7): 1821–1828. Published online 2007 Jan 25. doi: 10.1021/bi6024403
PMCID:
PMC2572083
AbstractArticlePDF–2.0M
19.
Structure and Mechanism of the Rebeccamycin Sugar 4′-O-Methyltransferase RebM
Shanteri Singh, Jason G. McCoy, Changsheng Zhang, Craig A. Bingman, George N. Phillips, Jr., Jon S. Thorson
J Biol Chem. 2008 Aug 15; 283(33): 22628–22636. doi: 10.1074/jbc.M800503200
PMCID:
PMC2504894
AbstractArticlePDF–449K
20.
Natural history of S-adenosylmethionine-binding proteins
Piotr Z Kozbial, Arcady R Mushegian
BMC Struct Biol. 2005; 5: 19. Published online 2005 Oct 14. doi: 10.1186/1472-6807-5-19
PMCID:
PMC1282579
AbstractArticlePDF–1.9M

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