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Select item 70738861.

Structure–Bioactivity Relationships of Lapatinib Derived Analogs against Schistosoma mansoni

Melissa J. Buskes, Monica Clements, Kelly A. Bachovchin, Hitesh B. Jalani, Allison Leonard, Seema Bag, Dana M. Klug, Baljinder Singh, Robert F. Campbell, Richard J. Sciotti, Nelly El-Sakkary, Conor R. Caffrey, Michael P. Pollastri, Lori Ferrins

ACS Med Chem Lett. 2020 Mar 12; 11(3): 258–265. Published online 2020 Jan 10. doi: 10.1021/acsmedchemlett.9b00455

PMCID:: PMC7073886

Abstract Article PDF–1.5M

Select item 70672122.

The chromatin bound proteome of the human malaria parasite

Gayani Batugedara, Xueqing M. Lu, Anita Saraf, Mihaela E. Sardiu, Anthony Cort, Steven Abel, Jacques Prudhomme, Michael P. Washburn, Laurence Florens, Evelien M. Bunnik, Karine G. Le Roch

Microb Genom. 2020 Feb; 6(2): e000327. Published online 2020 Feb 4. doi: 10.1099/mgen.0.000327

PMCID:: PMC7067212

Abstract Article PDF–3.4M

Select item 70643433.

Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes

Corinne von Känel, Sergio A Muñoz-Gómez, Silke Oeljeklaus, Christoph Wenger, Bettina Warscheid, Jeremy G Wideman, Anke Harsman, Andre Schneider

eLife. 2020; 9: e52560. Published online 2020 Feb 27. doi: 10.7554/eLife.52560

PMCID:: PMC7064343

Abstract Article PDF–4.0M

Select item 70642804.

Telomere Length in Renal Cell Carcinoma: The Jekyll and Hyde Biomarker of Ageing of the Kidney

Mariana Morais, Francisca Dias, Ana Luísa Teixeira, Rui Medeiros

Cancer Manag Res. 2020; 12: 1669–1679. Published online 2020 Mar 6. doi: 10.2147/CMAR.S211225

PMCID:: PMC7064280

Abstract Article PDF–1.8M

Select item 70589385.

‘High vault-age’: non-coding RNA control of autophagy

Magdalena Büscher, Rastislav Horos, Matthias W. Hentze

Open Biol. 2020 Feb; 10(2): 190307. Published online 2020 Feb 19. doi: 10.1098/rsob.190307

PMCID:: PMC7058938

Abstract Article PDF–783K

Select item 70575636.

Possible influence of Plasmodium/Trypanosoma co-infections on the vectorial capacity of Anopheles mosquitoes

Maty Fofana, Christian Mitri, Diawo Diallo, Brice Rotureau, Cheikh Tidiane Diagne, Alioune Gaye, Yamar Ba, Constentin Dieme, Mawlouth Diallo, Ibrahima Dia

BMC Res Notes. 2020; 13: 127. Published online 2020 Mar 4. doi: 10.1186/s13104-020-04977-8

PMCID:: PMC7057563

Abstract Article PDF–984K

Select item 70573657.

Crystal structure of 1-[(4-methylbenzene)sulfonyl]pyrrolidine

Brock A. Stenfors, Richard J. Staples, Shannon M. Biros, Felix N. Ngassa

Acta Crystallogr E Crystallogr Commun. 2020 Mar 1; 76(Pt 3): 452–455. Published online 2020 Feb 28. doi: 10.1107/S205698902000208X

PMCID:: PMC7057365

Abstract Article PDF–636K

Select item 70568418.

A CRISPR/Cas9-riboswitch-Based Method for Downregulation of Gene Expression in Trypanosoma cruzi

Noelia Lander, Teresa Cruz-Bustos, Roberto Docampo

Front Cell Infect Microbiol. 2020; 10: 68. Published online 2020 Feb 27. doi: 10.3389/fcimb.2020.00068

PMCID:: PMC7056841

Abstract Article PDF–976K

Select item 70559169.

Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes

Rudo Kieft, Yang Zhang, Alexandre P. Marand, Jose Dagoberto Moran, Robert Bridger, Lance Wells, Robert J. Schmitz, Robert Sabatini

PLoS Genet. 2020 Feb; 16(2): e1008390. Published online 2020 Feb 21. doi: 10.1371/journal.pgen.1008390

PMCID:: PMC7055916

Abstract Article PDF–2.8M

Select item 705589810.

The epidemiology of chronic kidney disease (CKD) in rural East Africa: A population-based study

Anthony N. Muiru, Edwin D. Charlebois, Laura B. Balzer, Dalsone Kwarisiima, Assurah Elly, Doug Black, Samuel Okiror, Jane Kabami, Mucunguzi Atukunda, Katherine Snyman, Maya Petersen, Moses Kamya, Diane Havlir, Michelle M. Estrella, Chi-yuan Hsu

PLoS One. 2020; 15(3): e0229649. Published online 2020 Mar 4. doi: 10.1371/journal.pone.0229649

PMCID:: PMC7055898

Abstract Article PDF–706K

Select item 705527011.

In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts

Alexandre Crépin, Jean-François Jégou, Sonia André, Florine Ecale, Anastasia Croitoru, Anne Cantereau, Jean-Marc Berjeaud, Ali Ladram, Julien Verdon

Sci Rep. 2020; 10: 3978. Published online 2020 Mar 4. doi: 10.1038/s41598-020-60829-2

PMCID:: PMC7055270

Abstract Article PDF–2.8M

Select item 705297612.

Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids

Anzhelika Butenko, Fred R. Opperdoes, Olga Flegontova, Aleš Horák, Vladimír Hampl, Patrick Keeling, Ryan M. R. Gawryluk, Denis Tikhonenkov, Pavel Flegontov, Julius Lukeš

BMC Biol. 2020; 18: 23. Published online 2020 Mar 2. doi: 10.1186/s12915-020-0754-1

PMCID:: PMC7052976

Abstract Article PDF–4.7M

Select item 705297213.

Comparative functional genomics analysis of cytochrome P450 gene superfamily in wheat and maize

Yixuan Li, Kaifa Wei

BMC Plant Biol. 2020; 20: 93. Published online 2020 Mar 2. doi: 10.1186/s12870-020-2288-7

PMCID:: PMC7052972

Abstract Article PDF–4.1M

Select item 705024414.

Comparative and evolutionary analyses of the divergence of plant oligosaccharyltransferase STT3 isoforms

Guanting Niu, Zhuqing Shao, Chuanfa Liu, Tianshu Chen, Qingsong Jiao, Zhi Hong

FEBS Open Bio. 2020 Mar; 10(3): 468–483. Published online 2020 Feb 19. doi: 10.1002/2211-5463.12804

PMCID:: PMC7050244

Abstract Article PDF–2.4M

Select item 705014515.

The draft nuclear genome sequence and predicted mitochondrial proteome of Andalucia godoyi, a protist with the most gene-rich and bacteria-like mitochondrial genome

Michael W. Gray, Gertraud Burger, Romain Derelle, Vladimír Klimeš, Michelle M. Leger, Matt Sarrasin, Čestmír Vlček, Andrew J. Roger, Marek Eliáš, B. Franz Lang

BMC Biol. 2020; 18: 22. Published online 2020 Mar 2. doi: 10.1186/s12915-020-0741-6

PMCID:: PMC7050145

Abstract Article PDF–4.3M

Select item 704975416.

Immunoinformatics and Vaccine Development: An Overview

Angus Nnamdi Oli, Wilson Okechukwu Obialor, Martins Ositadimma Ifeanyichukwu, Damian Chukwu Odimegwu, Jude Nnaemeka Okoyeh, George Ogonna Emechebe, Samson Adedeji Adejumo, Gordon C Ibeanu

Immunotargets Ther. 2020; 9: 13–30. Published online 2020 Feb 26. doi: 10.2147/ITT.S241064