RecName: Full=Cholinesterase; AltName: Full=Acylcholine acylhydrolase; - Protein

Change region shown

Customize view

Analyze this sequence

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Protein 3D Structure

Crystal structure of human butyrylcholinesterase in complex with 2-{1-[4-(12-Amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinolin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}-N-[4-hydroxy-3-methoxybenzyl]acetamide

PDB: 7AIY

Source: Homo sapiens

Method: X-ray Diffraction

Resolution: 2.937 Å

See all 58 structures...

Articles about the BCHE gene

Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study. [BMC Neurol. 2024]
Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study.
Schlake K, Teller J, Hinken L, Laser H, Lichtinghagen R, Schäfer A, Fegbeutel C, Weissenborn K, Jung C, Worthmann H, et al. BMC Neurol. 2024 Mar 1; 24(1):80. Epub 2024 Mar 1.
Progressions of the correlation between lipid metabolism and immune infiltration characteristics in gastric cancer and identification of BCHE as a potential biomarker. [Front Immunol. 2024]
Progressions of the correlation between lipid metabolism and immune infiltration characteristics in gastric cancer and identification of BCHE as a potential biomarker.
Wang S, Huang X, Zhao S, Lv J, Li Y, Wang S, Guo J, Wang Y, Wang R, Zhang M, et al. Front Immunol. 2024; 15:1327565. Epub 2024 Jan 31.
Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole. [J Phys Chem B. 2023]
Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole.
Zheng F, Hou S, Xue L, Yang W, Zhan CG. J Phys Chem B. 2023 Dec 21; 127(50):10723-10729. Epub 2023 Dec 8.

See all...

Reference sequence information

RefSeq genomic sequence
See the genomic reference sequence for the BCHE gene (NG_009031.1).
RefSeq protein
See the reference protein sequence for cholinesterase precursor (NP_000046.1).

More about the BCHE gene

This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits b...
Also Known As: BCHED, CHE1, CHE2, E1

Related information

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

LinkOut to external resources

P06276 [Domain Mapping of Disease Mut...]
P06276
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Recent activity

Clear Turn Off Turn On

RecName: Full=Cholinesterase; AltName: Full=Acylcholine acylhydrolase; AltName: ...
RecName: Full=Cholinesterase; AltName: Full=Acylcholine acylhydrolase; AltName: Full=Butyrylcholine esterase; AltName: Full=Choline esterase II; AltName: Full=Pseudocholinesterase; Flags: Precursor
gi|116353|sp|P06276.1|CHLE_HUMAN

Protein
RefSeq RNA Links for Gene (Select 590) (3)
Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Protein

Result Filters

Send to:

RecName: Full=Cholinesterase; AltName: Full=Acylcholine acylhydrolase; AltName: Full=Butyrylcholine esterase; AltName: Full=Choline esterase II; AltName: Full=Pseudocholinesterase; Flags: Precursor

Supplemental Content

Change region shown

Customize view

Features added by NCBI

Analyze this sequence

Protein 3D Structure

Articles about the BCHE gene

Reference sequence information

More about the BCHE gene

Related information

LinkOut to external resources

Recent activity