RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO; AltName: - Protein

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Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and β-cell function: In vitro studies using INS-1 cells and human pancreatic islets. [Life Sci. 2024]
Fat mass and obesity-associated (FTO) gene is essential for insulin secretion and β-cell function: In vitro studies using INS-1 cells and human pancreatic islets.
Taneera J, Khalique A, Abdrabh S, Mohammed AK, Bouzid A, El-Huneidi W, Bustanji Y, Sulaiman N, Albasha S, Saber-Ayad M, et al. Life Sci. 2024 Feb 15; 339:122421. Epub 2024 Jan 15.
Minor alleles of FTO rs9939609 and rs17817449 polymorphisms confer a higher risk of type 2 diabetes mellitus and dyslipidemia, but not coronary artery disease in a Chinese Han population. [Front Endocrinol (Lausanne). 2...]
Minor alleles of FTO rs9939609 and rs17817449 polymorphisms confer a higher risk of type 2 diabetes mellitus and dyslipidemia, but not coronary artery disease in a Chinese Han population.
Zhang Y, Chen L, Zhu J, Liu H, Xu L, Wu Y, He C, Song Y. Front Endocrinol (Lausanne). 2023; 14:1249070. Epub 2023 Dec 15.
FTO is a major genetic link between breast cancer, obesity, and diabetes. [Breast Cancer Res Treat. 2024]
FTO is a major genetic link between breast cancer, obesity, and diabetes.
Gholami M. Breast Cancer Res Treat. 2024 Feb; 204(1):159-169. Epub 2023 Dec 9.

RefSeq genomic sequence
See the genomic reference sequence for the FTO gene (NG_012969.2).
RefSeq protein isoforms
See 34 reference sequence protein isoforms for the FTO gene.

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Q9C0B1 [Domain Mapping of Disease Mut...]
Q9C0B1
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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Reactome [Reactome]
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reagents [ExactAntigen/Labome]
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RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO; AltName: Full=Fat m...
RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO; AltName: Full=Fat mass and obesity-associated protein; AltName: Full=U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; AltName: Full=U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; AltName: Full=mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; Short=m6A(m)-demethylase FTO; AltName: Full=mRNA N(6)-methyladenosine demethylase FTO; AltName: Full=tRNA N1-methyl adenine demethylase FTO
gi|148841515|sp|Q9C0B1.3|FTO_HUMAN

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