RecName: Full=Peroxisomal multifunctional enzyme type 2; Short=MFE-2; - Protein

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HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity. [Breast Cancer Res Treat. 2023]
HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity.
Arai N, Hattori N, Yamashita S, Liu YY, Ebata T, Takeuchi C, Takeshima H, Fujii S, Kondo H, Mukai H, et al. Breast Cancer Res Treat. 2023 Sep; 201(2):317-328. Epub 2023 Jun 28.
Rapid whole-genome sequencing identifies a homozygous novel variant, His540Arg, in HSD17B4 resulting in D-bifunctional protein deficiency disorder diagnosis. [Cold Spring Harb Mol Case Stud...]
Rapid whole-genome sequencing identifies a homozygous novel variant, His540Arg, in HSD17B4 resulting in D-bifunctional protein deficiency disorder diagnosis.
Savage L, Adams SD, James K, Chowdhury S, Rajasekaran S, Prokop JW, Bupp C. Cold Spring Harb Mol Case Stud. 2020 Dec; 6(6). Epub 2020 Dec 17.
Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. [Aging (Albany NY). 2020]
Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer.
Huang H, Liu R, Huang Y, Feng Y, Fu Y, Chen L, Chen Z, Cai Y, Zhang Y, Chen Y. Aging (Albany NY). 2020 Jul 17; 12(14):14699-14717. Epub 2020 Jul 17.

RefSeq genomic sequence
See the genomic reference sequence for the HSD17B4 gene (NG_008182.1).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the HSD17B4 gene.

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P51659 [Domain Mapping of Disease Mut...]
P51659
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
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Reactome
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ExactAntigen/Labome

RecName: Full=Peroxisomal multifunctional enzyme type 2; Short=MFE-2; AltName: F...
RecName: Full=Peroxisomal multifunctional enzyme type 2; Short=MFE-2; AltName: Full=17-beta-hydroxysteroid dehydrogenase 4; Short=17-beta-HSD 4; AltName: Full=D-bifunctional protein; Short=DBP; AltName: Full=Multifunctional protein 2; Short=MFP-2; AltName: Full=Short chain dehydrogenase/reductase family 8C member 1; Contains: RecName: Full=(3R)-hydroxyacyl-CoA dehydrogenase; Contains: RecName: Full=Enoyl-CoA hydratase 2; AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
gi|1706396|sp|P51659.3|DHB4_HUMAN

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