RecName: Full=ADP-sugar pyrophosphatase; AltName: Full=8-oxo-dGDP phos - Protein

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The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth. [Breast Cancer Res. 2024]
The novel phosphatase NUDT5 is a critical regulator of triple-negative breast cancer growth.
Qian J, Ma Y, Tahaney WM, Moyer CL, Lanier A, Hill J, Coleman D, Koupaei N, Hilsenbeck SG, Savage MI, et al. Breast Cancer Res. 2024 Feb 5; 26(1):23. Epub 2024 Feb 5.
NUDT5-Determines the fate of head and neck squamous cell carcinoma cells under endoplasmic reticulum stress by catalyzing nuclear ATP production to promote DNA repair. [Oral Oncol. 2023]
NUDT5-Determines the fate of head and neck squamous cell carcinoma cells under endoplasmic reticulum stress by catalyzing nuclear ATP production to promote DNA repair.
Ding H, Wu C, Sun W, Zhan Q, Huang Y, Liao N, Jiang Z, Wang K, Li Y. Oral Oncol. 2023 Jun; 141:106397. Epub 2023 May 6.
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway. [Toxicol Appl Pharmacol. 2022]
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
Tan D, Zhang Y. Toxicol Appl Pharmacol. 2022 Apr 15; 441:115968. Epub 2022 Mar 2.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the NUDT5 gene.

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
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RecName: Full=ADP-sugar pyrophosphatase; AltName: Full=8-oxo-dGDP phosphatase; A...
RecName: Full=ADP-sugar pyrophosphatase; AltName: Full=8-oxo-dGDP phosphatase; AltName: Full=Nuclear ATP-synthesis protein NUDIX5; AltName: Full=Nucleoside diphosphate-linked moiety X motif 5; Short=Nudix motif 5; Short=hNUDT5; AltName: Full=YSA1H
gi|20455192|sp|Q9UKK9.1|NUDT5_HUMAN

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