RecName: Full=Glutaminyl-peptide cyclotransferase; AltName: Full=Gluta - Protein

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Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression. [Cancer Biol Ther. 2023]
Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression.
Liu L, Liu H, Liu L, Huang Q, Yang C, Cheng P, Ren S, Zhang J, Yu M, Ma X, et al. Cancer Biol Ther. 2023 Dec 31; 24(1):2228497.
A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. [J Mol Biol. 2021]
A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
Huang KF, Huang JS, Wu ML, Hsieh WL, Hsu KC, Hsu HL, Ko TP, Wang AH. J Mol Biol. 2021 Jun 25; 433(13):166960. Epub 2021 Mar 25.
Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. [Biochemistry. 2020]
Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.
Kupski O, Funk LM, Sautner V, Seifert F, Worbs B, Ramsbeck D, Meyer F, Diederichsen U, Buchholz M, Schilling S, et al. Biochemistry. 2020 Jul 21; 59(28):2585-2591. Epub 2020 Jun 29.

RefSeq protein
See the reference protein sequence for glutaminyl-peptide cyclotransferase precursor (NP_036545.1).

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Related structures

Q16769 [Domain Mapping of Disease Mut...]
Q16769
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
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Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Glutaminyl-peptide cyclotransferase; AltName: Full=Glutaminyl cycl...
RecName: Full=Glutaminyl-peptide cyclotransferase; AltName: Full=Glutaminyl cyclase; Short=QC; Short=sQC; AltName: Full=Glutaminyl-tRNA cyclotransferase; AltName: Full=Glutamyl cyclase; Short=EC; Flags: Precursor
gi|2498824|sp|Q16769.1|QPCT_HUMAN

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