RecName: Full=T-lymphocyte activation antigen CD86; AltName: Full=Acti - Protein

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B cell-mediated CD4 T-cell costimulation via CD86 exacerbates pro-inflammatory cytokine production during autoimmune intestinal inflammation. [Mucosal Immunol. 2024]
B cell-mediated CD4 T-cell costimulation via CD86 exacerbates pro-inflammatory cytokine production during autoimmune intestinal inflammation.
Gadjalova I, Heinze JM, Goess MC, Hofmann J, Buck A, Weber MC, Blissenbach B, Kampick M, Krut O, Steiger K, et al. Mucosal Immunol. 2024 Feb; 17(1):67-80. Epub 2023 Oct 31.
The levels of serum soluble CD86 are correlated with the expression of CD86 variant 3 gene and are prognostic indicators in patients with myeloma. [Exp Hematol. 2023]
The levels of serum soluble CD86 are correlated with the expression of CD86 variant 3 gene and are prognostic indicators in patients with myeloma.
Kinoshita R, Ishibashi M, Handa H, Sasaki M, Imai Y, Tanaka N, Ito S, Sunakawa-Kii M, Kaito Y, Asayama T, et al. Exp Hematol. 2023 May; 121:38-47.e2. Epub 2023 Feb 14.
Human and viral membrane-associated E3 ubiquitin ligases MARCH1 and MIR2 recognize different features of CD86 to downregulate surface expression. [J Biol Chem. 2021]
Human and viral membrane-associated E3 ubiquitin ligases MARCH1 and MIR2 recognize different features of CD86 to downregulate surface expression.
Trenker R, Wu X, Nguyen JV, Wilcox S, Rubin AF, Call ME, Call MJ. J Biol Chem. 2021 Jul; 297(1):100900. Epub 2021 Jun 19.

RefSeq genomic sequence
See the genomic reference sequence for the CD86 gene (NG_029928.2).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the CD86 gene.

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P42081 [Domain Mapping of Disease Mut...]
P42081
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=T-lymphocyte activation antigen CD86; AltName: Full=Activation B7-...
RecName: Full=T-lymphocyte activation antigen CD86; AltName: Full=Activation B7-2 antigen; AltName: Full=B70; AltName: Full=BU63; AltName: Full=CTLA-4 counter-receptor B7.2; AltName: Full=FUN-1; AltName: CD_antigen=CD86; Flags: Precursor
gi|317373339|sp|P42081.2|CD86_HUMAN

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