RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase - Protein

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DELE1 oligomerization promotes integrated stress response activation. [Nat Struct Mol Biol. 2023]
DELE1 oligomerization promotes integrated stress response activation.
Yang J, Baron KR, Pride DE, Schneemann A, Guo X, Chen W, Song AS, Aviles G, Kampmann M, Wiseman RL, et al. Nat Struct Mol Biol. 2023 Sep; 30(9):1295-1302. Epub 2023 Aug 7.
Activation of HRI is mediated by Hsp90 during stress through modulation of the HRI-Hsp90 complex. [Int J Biol Macromol. 2018]
Activation of HRI is mediated by Hsp90 during stress through modulation of the HRI-Hsp90 complex.
Berwal SK, Bhatia V, Bendre A, Suresh CG, Chatterjee S, Pal JK. Int J Biol Macromol. 2018 Oct 15; 118(Pt B):1604-1613. Epub 2018 Jul 3.
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. [Science. 2018]
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.
Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, et al. Science. 2018 Jul 20; 361(6399):285-290.

RefSeq protein isoforms
See 4 reference sequence protein isoforms for the EIF2AK1 gene.

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Q9BQI3 [Domain Mapping of Disease Mut...]
Q9BQI3
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName...
RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1; AltName: Full=Heme-controlled repressor; Short=HCR; AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; AltName: Full=Heme-regulated inhibitor; Short=hHRI; AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase
gi|32172458|sp|Q9BQI3.2|E2AK1_HUMAN

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