WD repeat-containing protein 53 isoform a [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. [Nat Cell Biol. 2006]
CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H. Nat Cell Biol. 2006 Nov; 8(11):1277-83. Epub 2006 Oct 15.
The E3 ubiquitin ligase APC/C(C)(dh1) degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis. [EMBO J. 2017]
The E3 ubiquitin ligase APC/C(C)(dh1) degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
Liu X, Zong W, Li T, Wang Y, Xu X, Zhou ZW, Wang ZQ. EMBO J. 2017 Dec 15; 36(24):3666-3681. Epub 2017 Nov 17.
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications. [ACS Chem Biol. 2022]
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications.
Salguero AL, Chen M, Balana AT, Chu N, Jiang H, Palanski BA, Bae H, Wright KM, Nathan S, Zhu H, et al. ACS Chem Biol. 2022 Jan 21; 17(1):68-76. Epub 2021 Dec 23.

RefSeq mRNA
See reference mRNA sequence for the WDR53 gene (NM_182627.3).
RefSeq protein isoforms
See 17 reference sequence protein isoforms for the WDR53 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_872433 [Domain Mapping of Disease Mut...]
NP_872433
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

WD repeat-containing protein 53 isoform a [Homo sapiens]
WD repeat-containing protein 53 isoform a [Homo sapiens]
gi|32699064|ref|NP_872433.1|

Protein
Sex Chromosomes
Sex Chromosomes
The homologous chromosomes that are dissimilar in the heterogametic sex. There are the X CHROMOSOME, the Y CHROMOSOME, and the W, Z chromosomes (in animals in which the female...<br/>Year introduced: 1968

MeSH
Perilipin-1
Perilipin-1
A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artheros...<br/>Year introduced: 2017 (1991)

MeSH

Your browsing activity is empty.

Activity recording is turned off.

Protein