RecName: Full=Actin, aortic smooth muscle; AltName: Full=Alpha-actin-2 - Protein

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Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model. [J Hum Genet. 2024]
Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model.
Sebastian WA, Inoue M, Shimizu N, Sato R, Oguri S, Itonaga T, Kishimoto S, Shiraishi H, Hanada T, Ihara K. J Hum Genet. 2024 Apr; 69(3-4):133-138. Epub 2024 Feb 5.
A highly penetrant ACTA2 mutation of thoracic aortic disease. [J Cardiothorac Surg. 2023]
A highly penetrant ACTA2 mutation of thoracic aortic disease.
Bobba CM, Azarrafiy R, Spratt JR, Hendrickson J, Martin TD, Arnaoutakis GJ, Jeng EI, Beaver TM. J Cardiothorac Surg. 2023 Dec 4; 18(1):352. Epub 2023 Dec 4.
Smooth Muscle-Alpha Actin R149C Pathogenic Variant Downregulates Integrin Recruitment at Cell-Matrix Adhesions and Decreases Cellular Contractility. [Int J Mol Sci. 2023]
Smooth Muscle-Alpha Actin R149C Pathogenic Variant Downregulates Integrin Recruitment at Cell-Matrix Adhesions and Decreases Cellular Contractility.
Ojha KR, Kim H, Padgham S, Hopkins L, Zamen RJ, Chattopadhyay A, Han G, Milewicz DM, Massett MP, Trache A. Int J Mol Sci. 2023 Jun 1; 24(11). Epub 2023 Jun 1.

RefSeq genomic sequence
See the genomic reference sequence for the ACTA2 gene (NG_011541.1).
RefSeq protein isoforms
See 11 reference sequence protein isoforms for the ACTA2 gene.

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Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
P62736 [Domain Mapping of Disease Mut...]
P62736
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Actin, aortic smooth muscle; AltName: Full=Alpha-actin-2; AltName:...
RecName: Full=Actin, aortic smooth muscle; AltName: Full=Alpha-actin-2; AltName: Full=Cell growth-inhibiting gene 46 protein; Contains: RecName: Full=Actin, aortic smooth muscle, intermediate form; Flags: Precursor
gi|51316972|sp|P62736.1|ACTA_HUMAN

Protein
fbxc-55 F-box C protein [Caenorhabditis elegans]
fbxc-55 F-box C protein [Caenorhabditis elegans]
Gene ID:189559

Gene
sri-57 Serpentine Receptor, class I [Caenorhabditis elegans]
sri-57 Serpentine Receptor, class I [Caenorhabditis elegans]
Gene ID:184844

Gene
spe-38 Uncharacterized protein [Caenorhabditis elegans]
spe-38 Uncharacterized protein [Caenorhabditis elegans]
Gene ID:190181

Gene

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Protein