RecName: Full=Cytochrome P450 7A1; AltName: Full=24-hydroxycholesterol - Protein

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CYP7A1 Gene Induction via SHP-Dependent or Independent Mechanisms can Increase the Risk of Drug-Induced Liver Injury Independently or in Synergy with BSEP Inhibition. [Drug Metab Dispos. 2024]
CYP7A1 Gene Induction via SHP-Dependent or Independent Mechanisms can Increase the Risk of Drug-Induced Liver Injury Independently or in Synergy with BSEP Inhibition.
Niu C, Xie X, Liu R, Liang X, Hu Y, Lai Y. Drug Metab Dispos. 2024 Apr 16; 52(5):432-441. Epub 2024 Apr 16.
Pharmacological modulation of cholesterol 7α-hydroxylase (CYP7A1) as a therapeutic strategy for hypercholesterolemia. [Biochem Pharmacol. 2024]
Pharmacological modulation of cholesterol 7α-hydroxylase (CYP7A1) as a therapeutic strategy for hypercholesterolemia.
Yu Cai Lim M, Kiat Ho H. Biochem Pharmacol. 2024 Feb; 220:115985. Epub 2023 Dec 26.
[Cholesterol 7α-Hydroxylase Gene-204A/C Polymorphism in Normal and Gestational Diabetic Pregnancies]. [Sichuan Da Xue Xue Bao Yi Xue ...]
[Cholesterol 7α-Hydroxylase Gene-204A/C Polymorphism in Normal and Gestational Diabetic Pregnancies].
Liu SX, Bai H, Guan LB, Liu XH, Fan P, Zhou M, Wu YJ, Tang FM, Wang YF, Li DH. Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Mar; 54(2):361-366.

RefSeq genomic sequence
See the genomic reference sequence for the CYP7A1 gene (NG_007969.1).
RefSeq protein
See the reference protein sequence for cytochrome P450 7A1 (NP_000771.2).

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P22680 [Domain Mapping of Disease Mut...]
P22680
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Cytochrome P450 7A1; AltName: Full=24-hydroxycholesterol 7-alpha-h...
RecName: Full=Cytochrome P450 7A1; AltName: Full=24-hydroxycholesterol 7-alpha-hydroxylase; AltName: Full=CYPVII; AltName: Full=Cholesterol 7-alpha-hydroxylase; AltName: Full=Cholesterol 7-alpha-monooxygenase
gi|544084|sp|P22680.2|CP7A1_HUMAN

Protein
Cyclophilin A
Cyclophilin A
A 17-KDa cytoplasmic PEPTIDYLPROLYL ISOMERASE involved in immunoregulation. It is a member of the cyclophilin family of proteins that binds to CYCLOSPORINE....<br/>Year introduced: 2001

MeSH
Natural Cytotoxicity Triggering Receptor 2
Natural Cytotoxicity Triggering Receptor 2
A 44-kD stimulatory receptor found on activated NATURAL KILLER CELLS. It has specificity for VIRAL HEMAGGLUTININS that are expressed on infected cells....<br/>Year introduced: 2009

MeSH
Retinopathy of Prematurity
Retinopathy of Prematurity
A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuos...<br/>Year introduced: 1987

MeSH
Cryptosporidium baileyi
Cryptosporidium baileyi

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