RecName: Full=Insulin receptor substrate 1; Short=IRS-1; AltName: Full - Protein

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IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis. [Mol Cell Neurosci. 2022]
IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis.
Sánchez-Sarasúa S, Meseguer-Beltrán M, García-Díaz C, Beltrán-Bretones MT, ElMlili N, Sánchez-Pérez AM. Mol Cell Neurosci. 2022 Jan; 118:103693. Epub 2021 Dec 20.
Activation of Wnt/β-catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS-1. [J Neurochem. 2021]
Activation of Wnt/β-catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS-1.
Tian S, Tan S, Jia W, Zhao J, Sun X. J Neurochem. 2021 May; 157(3):467-478. Epub 2020 Dec 31.
Insulin‑receptor substrate 1 protects against injury in endothelial cell models of ox‑LDL‑induced atherosclerosis by inhibiting ER stress/oxidative stress‑mediated apoptosis and activating the Akt/FoxO1 signaling pathway. [Int J Mol Med. 2020]
Insulin‑receptor substrate 1 protects against injury in endothelial cell models of ox‑LDL‑induced atherosclerosis by inhibiting ER stress/oxidative stress‑mediated apoptosis and activating the Akt/FoxO1 signaling pathway.
Liu J, Yi X, Tao Y, Wang Y, Xu Z. Int J Mol Med. 2020 Nov; 46(5):1671-1682. Epub 2020 Sep 15.

RefSeq protein
See the reference protein sequence for insulin receptor substrate 1 (NP_037101.2).

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
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Reactome [Reactome]
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reagent reviews [ExactAntigen/Labome]
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RecName: Full=Insulin receptor substrate 1; Short=IRS-1; AltName: Full=pp185
RecName: Full=Insulin receptor substrate 1; Short=IRS-1; AltName: Full=pp185
gi|547740|sp|P35570.1|IRS1_RAT

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