RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; Alt - Protein

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Defective microbial sensing and clearance in perianal Crohn's disease: a role for complement factor B. [Gut. 2023]
Defective microbial sensing and clearance in perianal Crohn's disease: a role for complement factor B.
Ghate A, Uhlig HH. Gut. 2023 Nov; 72(11):2010-2012. Epub 2023 Apr 25.
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. [Gut. 2023]
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, et al. Gut. 2023 Nov; 72(11):2068-2080. Epub 2023 Apr 20.
Functional variant rs12614 in CFB confers a low risk of IgA nephropathy by attenuating complement alternative pathway activation in Han Chinese. [Front Immunol. 2022]
Functional variant rs12614 in CFB confers a low risk of IgA nephropathy by attenuating complement alternative pathway activation in Han Chinese.
Shi DC, Feng SZ, Zhong Z, Cai L, Wang M, Fu DY, Yu XQ, Li M. Front Immunol. 2022; 13:973169. Epub 2022 Oct 13.

RefSeq genomic sequence
See the genomic reference sequence for the CFB gene (NG_008191.1).

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P00751 [Domain Mapping of Disease Mut...]
P00751
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
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Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; AltName: Full...
RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; AltName: Full=Glycine-rich beta glycoprotein; Short=GBG; AltName: Full=PBF2; AltName: Full=Properdin factor B; Contains: RecName: Full=Complement factor B Ba fragment; Contains: RecName: Full=Complement factor B Bb fragment; Flags: Precursor
gi|584908|sp|P00751.2|CFAB_HUMAN

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